Systemic Lupus Erythematosus - 4th Edition - ISBN: 9780124339019, 9780080474540

Systemic Lupus Erythematosus

4th Edition

Editors: Robert Lahita
eBook ISBN: 9780080474540
Hardcover ISBN: 9780124339019
Imprint: Academic Press
Published Date: 12th May 2004
Page Count: 1343
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Systemic Lupus Erythematosus, Fourth Edition, provides an understanding of the basic mechanisms as well as the diagnostic and therapeutic aspects of lupus. This book is attractive to both the investigative community and clinicians. As lupus has become a paradigm for the study of autoimmune disease, immunologists investigating autoimmunity are becoming more interested in lupus. Basic immunology of phospholipid antibodies, clotting abnormailities, issues concerning pathogenetic fit with SLE, and newest methods of therapy of APLS are given in this newest edition of a classic reference.

Key Features

  • Comprehensive current coverage of basic models of etiology and pathogenesis
  • Complete catalog of autoantibodies produced
  • Includes an outstanding review of imaging techniques for the diagnosis of lupus and its complications for each organ system
  • Includes CD-ROM of images excellent for teaching purposes and downloading into presentations


Immunologists, basic and clinical researchers, rheumatologists, dermatologists, clinical researchers studying women and health, hospital and medical school libraries.

Table of Contents

Foreword <BR id=""CRLF"">Introduction to 4th Edition<BR id=""CRLF"">Pathogenesis <BR id=""CRLF"">Autoimmunity and Autoimmune Diseases like Systemic Lupus Erythematosus <BR id=""CRLF"">Overview of Cellular Immune Function in Systemic Lupus Erythematosus<BR id=""CRLF"">Etiopathogenesis of Systemic Lupus Erythematosus: The Itineraries of Three Troikas<BR id=""CRLF"">MHC Class II and Non-MHC Genes in the Pathogenesis of Systemic Lupus Erythematosus <BR id=""CRLF"">Genetic Susceptibility and Class III Complement Genes<BR id=""CRLF"">Complement Deficiency and Systemic Lupus Erythematosus<BR id=""CRLF"">Gender and Age in Systemic Lupus Erythematosus<BR id=""CRLF"">Animal Models <BR id=""CRLF"">Genes and Genetics of Murine Systemic Lupus Erythematosus<BR id=""CRLF"">Systemic Lupus Erythematosus in Domestic Animals<BR id=""CRLF""><BR id=""CRLF"">Autoantibodies and Antigens<BR id=""CRLF"">Anti-DNA Antibodies : Structure, Assembly and Diversity <BR id=""CRLF"">Antibodies to Cytoplasmic Antigens <BR id=""CRLF"">Antihistone Antibodies<BR id=""CRLF"">Antibodies to Non-Histone Agents in Systemic Lupus Erythematosus<BR id=""CRLF"">Immune Complexes <BR id=""CRLF"">Origins of Antinuclear Antibodies<BR id=""CRLF""><BR id=""CRLF"">Clinical Approach to Diagnosis<BR id=""CRLF"">The Clinical Presentation of Systemic Lupus Erythematosus<BR id=""CRLF"">Neonatal Systemic Lupus Erythematosus Syndromes<BR id=""CRLF"">Systemic Lupus Erythematosus in Childhood<BR id=""CRLF"">Imaging of Systemic Lupus Erythematosus: State of the Art<BR id=""CRLF"">Monitoring Patients and Systemic Lupus Erythematosus<BR id=""CRLF"">Laboratory Evaluation of Patients with Systemic Lupus Erythematosus<BR id=""CRLF"">Systemic Lupus Erythematosus Pregnancy <BR id=""CRLF"">Epidemiology of Systemic Lupus Erythematosus<BR id=""CRLF"">Overlap Syndromes: Mixed Connective Tissue Disease and Sjögren's Syndrome<BR id=""CRLF"">Systemic Lupus Erythematosus and Fibromyalgia <BR id=""CRLF""><BR id=""CRLF"">Organs Affected by Systemic Lupus Erythematosus <BR id=""CRLF"">Nervous system:<BR id=""CRLF"">Central Nervous System Systemic Lupus Erythematosus <BR id=""CRLF"">Psychiatric Aspects of Systemic Lupus Erythematosus<BR id=""CRLF"">Cognitive Dysfunction in Systemic Lupus Erythematosus<BR id=""CRLF"">Dermatology:<BR id=""CRLF"">Systemic Lupus Erythematosus and the Skin<BR id=""CRLF"">Renal:<BR id=""CRLF"">Systemic Lupus Erythematosus and the Kidney<BR id=""CRLF"">Cardiopulmonary:<BR id=""CRLF"">Cardiovascular Systemic Lupus Erythematosus<BR id=""CRLF"">Systemic Lupus Erythematosus and the Cardiovascular System: Vasculitis<BR id=""CRLF"">Systemic Lupus Erythematosus and the Lung<BR id=""CRLF"">Gastrointestinal:<BR id=""CRLF"">Nonhepatic Gastrointestinal Manifestations of Systemic Lupus Erythematosus<BR id=""CRLF"">Hepatic Disease and Systemic Lupus Erythematosus: Coincidence or Converence<BR id=""CRLF"">Hematology:<BR id=""CRLF"">The Cellular Hematology of Systemic Lupus Erythematosus<BR id=""CRLF"">Musculoskeletal:<BR id=""CRLF"">Articular Manifestations of Systemic Lupus Erythematosus<BR id=""CRLF"">Osteoporosis and Metabolic Bone Disease in Systemic Lupus Erythematosus<BR id=""CRLF""><BR id=""CRLF"">Specific Syndromes<BR id=""CRLF"">Phospholipid Syndrome:<BR id=""CRLF"">Immunology of Antiphospholipid Antibodies and Co-factors<BR id=""CRLF"">The Clinical Aspects of the Antiphospholipid Syndrome <BR id=""CRLF"">The Catastrophic Phospholipid Syndrome<BR id=""CRLF"">Hematology: Coagulation Problems<BR id=""CRLF"">The Antiphospholipid Syndrome: Pathogenesis and Implications for Systemic Lupus Erythematosus<BR id=""CRLF"">Drug Induced Systemic Lupus Erythematosus:<BR id=""CRLF"">Pathophysiology of Drug-Induced Systemic Lupus Erythematosus<BR id=""CRLF"">Drug and Environmental Systemic Lupus Erythematosus: Clinical Manifestations and Differences <BR id=""CRLF"">Therapy of Systemic Lupus Erythematosus<BR id=""CRLF"">Corticosteroid Use in Systemic Lupus Erythematosus<BR id=""CRLF"">Antimalarials and Immunosuppresive Therapies<BR id=""CRLF"">Unproven and Experimental Therapies


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© Academic Press 2004
Academic Press
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About the Editor

Robert Lahita

Affiliations and Expertise

ROBERT G. LAHITA MD, PhD Professor of Medicine, Adjunct Professor of Biochemistry and Molecular Biology UMDNJ, New Jersey Medical School Vice President and Chairman of Medicine Newark Beth Israel Medical Center Newark, NJ, USA


From Previous Edition: "This book successfully links basic science with clinical medicine, providing a framework within which to understand this complex disease. As Lahita states in the introduction, 'The history of discovery is now in the log phase of growth.' The third edition of Systemic Lupus Erythematosus conveys the excitement and the breadth of this dynamic field. This volume will be an excellent resource for basic and clinical scientists, as well as for the students of imunology and rheumatology. The chapters are well-referenced and can be read independently- as befits a reference book." -Jane E. Salmon, Weill Medical College, Cornell University, New York, USA (March 2000)

Ratings and Reviews