Synthetic Biology and Metabolic Engineering in Plants and Microbes Part A: Metabolism in Microbes

Synthetic Biology and Metabolic Engineering in Plants and Microbes Part A: Metabolism in Microbes

1st Edition - July 11, 2016
This is the Latest Edition
  • Editor: Sarah O'Connor
  • eBook ISBN: 9780128046166
  • Hardcover ISBN: 9780128045848

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Description

Synthetic Biology and Metabolic Engineering in Plants and Microbes: Part A, the new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways.

Key Features

  • Continues the legacy of this premier serial with quality chapters authored by leaders in the field
  • Contains two volumes covering research methods in synthetic biology and metabolic engineering in plants and microbes
  • Presents sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways

Readership

Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists.

Table of Contents

  • 1. Directing Biosynthesis: Practical Supply of Natural and Unnatural Cyanobactins
    Debosmita Sardar, Ma Diarey Tianero and Eric W. Schmidt
    2. Synthetic Biology Approaches to New Bisindoles
    Lona M. Alkhalaf, Yi-Ling Du and Katherine S. Ryan
    3. Enzymatic [4+2] Cycloadditions in the Biosynthesis of Spirotetramates and Spirotetronates
    Bo Pang, Guannan Zhong, Zhijun Tang and Wen Liu
    4. Application and Modification of Flavin-Dependent Halogenases
    Karl-Heinz van Pée, Daniela Milbredt, Eugenio Patallo, Veit Weichold and Maria Gajewi
    5. Engineering Flavin-Dependent Halogenases
    James T. Payne, Mary C. Andorfer and Jared C. Lewis
    6. Heterologous Expression of Fungal Secondary Metabolite Pathways in the Aspergillus Nidulans Host System
    Johannes W. A. van Dijk and Clay C. C. Wang
    7. Plug-and-Play Benzylisoquinoline Alkaloid Biosynthetic Gene Discovery in Engineered Yeast
    Jeremy S. Morris, Mehran Dastmalchi, Jing Li, Limei Chang, Xue Chen, Jillian M. Hagel and  Peter J. Facchini
    8. Optimizing Metabolic Pathways for the Improved Production of Natural Products
    J. Andrew Jones and Mattheos A. G. Koffas
    9. Reconstituting Plant Secondary Metabolism in Saccharomyces Cerevisiae for Production of High-Value Benzylisoquinoline Alkaloids
    Michael E. Pyne, Lauren Narcross, Elena Fossati, Leanne Bourgeois, Euan Burton, Nicholas D. Gold and Vincent J.J. Martin
    10. Engineering Microbes to Synthesize Plant Isoprenoids
    Kang Zhou, Steven Edgar and Gregory Stephanopoulos
    11. Natural Product Biosynthesis in Escherichia Coli: Mentha Monoterpenoids
    Helen S. Toogood, Shirley Tait, Adrian Jervis, Aisling Ní Cheallaigh, Luke Humphreys, Eriko Takano, John M. Gardiner and Nigel S. Scrutton
    12. High-Efficiency Genome Editing of Streptomyces Species by an Engineered Crispr/Cas System
    Yajie Wang, Ryan E. Cobb and Huimin Zhao
    13. Rapid optimization of engineered metabolic pathways with Serine Integrase Recombinational Assembly (SIRA)
    Christine Merrick, Caroline Wardrope, Jane Paget, Sean Colloms and Susan Rosser
    14. Rewiring Riboswitches to Create New Genetic Circuits in Bacteria
    Christopher J. Robinson, Daniel Medina-Stacey, Ming-Cheng Wu, Helen A. Vincent and Jason Micklefield

Product details

  • No. of pages: 396
  • Language: English
  • Copyright: © Academic Press 2016
  • Published: July 11, 2016
  • Imprint: Academic Press
  • eBook ISBN: 9780128046166
  • Hardcover ISBN: 9780128045848
  • About the Serial Volume Editor

    Sarah O'Connor

    John Innes Centre, Norwich Research Park, UK

    Affiliations and Expertise

    John Innes Centre, Norwich Research Park, UK