Synthesis of Essential Drugs

Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs.

This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO’s Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms.

Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry.

• Provides a brief description of methods of synthesis, activity and implementation of all drug types
• Includes synonyms
• Includes over 2300 references

Chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students

1. General Anesthetics
   
2. Local Anesthetics
   
3. Analgesics
   
4. Hypnotics and Sedatives
   
5. Anxiolitics (Tranquilizers)
   
6. Antipsycotics (Neuroleptics)
   
7. Antidepressants
   
8. Central Nervous System Stimulants
   
9. Antiepileptics
   
10. Anti-Parkinson Drugs
    
11. Adrenegic (Sympatomimetic) Drugs
    
12. Adrenoblocking Drugs
    
13. Cholinomimetics
    
14. Anticholinergic Drugs
    
15. Muscle Relaxants
    
16. Antihistamine Drugs
    
17. Cardiac Glycosides and Other Inotropes
    
18. Drugs for Tachyarrhytmias
    
19. Antianginal Drugs
    
20. Agents Used in Hyperlipoproteinemia
    
21. Diuretics
    
22. Antihypertensive Drugs
    
23. Drugs for Treating of Pulmonary Diseases
    
24. Anticoagulants, Antiagregants, Trombolytics and Hemostatics
    
25. Thyroid and Parathyroid Drugs
    
26. Insulin and Synthetic Hypoglycemic Agents
    
27. Corticosteroids
    
28. Female Sex Hormones
    
29. Male Sex Hormones and Anabolics
    
30. Antineoplastic Agents
    
31. Immunopharmacologic Drugs
    
32. Antibiotics
    
33. Antimicrobials
    
34. Antimicobacterials
    
35. Antifungal Drugs
    
36. Antiviral Drugs
    
37. Antiprotozoal Drugs
    
38. Antihelmint Drugs