Synthesis of Essential Drugs

1st Edition

Print ISBN: 9780444550675
eBook ISBN: 9780080462127
Imprint: Elsevier Science
Published Date: 10th March 2006
Page Count: 634
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This book represents an effort to express a long overdue need of compiling information which has been accumulated over the course of more than 30 years of our work in the area of the synthesis of medicinal drugs. Our effort fills obvious gaps that exist in the literature of drug synthesis.

The synthesis of various groups of drugs are presented in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists.

Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed description of methods for their synthesis.

Of the thousands of drugs existing on the pharmaceutical market, we mainly discuss generic drugs that are included in the WHO’s "Essential List of Drugs."

For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms.

This book will provide the kind of information that will be of interest to those who work, or plan to begin work in the captivating areas of biologically active compounds and the synthesis of medicinal drugs.

Key Features

  • Provides a brief description of methods of synthesis, activity and implementation of all drug types
  • Includes synonyms
  • Includes over 2300 references


Chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students

Table of Contents

  1. General Anesthetics
  2. Local Anesthetics
  3. Analgesics
  4. Hypnotics and Sedatives
  5. Anxiolitics (Tranquilizers)
  6. Antipsycotics (Neuroleptics)
  7. Antidepressants
  8. Central Nervous System Stimulants
  9. Antiepileptics
  10. Anti-Parkinson Drugs
  11. Adrenegic (Sympatomimetic) Drugs
  12. Adrenoblocking Drugs
  13. Cholinomimetics
  14. Anticholinergic Drugs
  15. Muscle Relaxants
  16. Antihistamine Drugs
  17. Cardiac Glycosides and Other Inotropes
  18. Drugs for Tachyarrhytmias
  19. Antianginal Drugs
  20. Agents Used in Hyperlipoproteinemia
  21. Diuretics
  22. Antihypertensive Drugs
  23. Drugs for Treating of Pulmonary Diseases
  24. Anticoagulants, Antiagregants, Trombolytics and Hemostatics
  25. Thyroid and Parathyroid Drugs
  26. Insulin and Synthetic Hypoglycemic Agents
  27. Corticosteroids
  28. Female Sex Hormones
  29. Male Sex Hormones and Anabolics
  30. Antineoplastic Agents
  31. Immunopharmacologic Drugs
  32. Antibiotics
  33. Antimicrobials
  34. Antimicobacterials
  35. Antifungal Drugs
  36. Antiviral Drugs
  37. Antiprotozoal Drugs
  38. Antihelmint Drugs


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© Elsevier Science 2006
Elsevier Science
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* Provides a brief description of methods of synthesis, activity and implementation of all drug types * Includes synonyms * Includes over 2300 references