Swaiman's Pediatric Neurology - 6th Edition - ISBN: 9780323374828

Swaiman's Pediatric Neurology

6th Edition

Principles and Practice

Authors: Kenneth Swaiman Stephen Ashwal Donna Ferriero Nina Schor Richard Finkel Andrea Gropman Phillip Pearl
eBook ISBN: 9780323374811
eBook ISBN: 9780323374828
Imprint: Elsevier
Published Date: 15th March 2017
Page Count: 2969
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Table of Contents

PART I
Clinical Evaluation

1 General Aspects of the Patient’s Neurologic History
2 Neurologic Examination of the Older Child
3 Neurologic Examination after the Newborn Period Until 2 Years of Age
4 Neurologic Examination of the Term and Preterm Infant
5 Muscular Tone and Gait Disturbances
6 Vision Loss
7 Hearing Impairment
8 Vertigo
9 Taste and Smell
10 Neuropsychological Assessment

PART II
Neurodiagnostic Testing
11 Spinal Fluid Examination
12 Pediatric Neuroimaging
13 Pediatric Neurophysiologic Evaluation

PART III
Emerging Neuroscience Concepts
14 Microstructural and Functional Connectivity in the Developing Brain
15 Stem Cell Transplantation for Childhood Neurologic Disorders
16 Cellular and Animal Models of Neurologic Disease

PART IV
Perinatal Acquired and Congenital Neurologic Disorders

17 Neonatal Neurointensive Care
18 Neonatal Seizures
19 Hypoxic-Ischemic Brain Injury in the Term Newborn
20 Cerebrovascular Disorders in the Newborn
21 Neonatal Nervous System Trauma
22 Injury to the Developing Preterm Brain: Intraventricular Hemorrhage and White Matter Injury
Video 22.1 Endoscopic View of Clot at the Foramen of Monro
Video 22.2 Endoscopic Third Ventriculostomy in an Infant with Posthemorrhagic Hydrocephalus
23 Perinatal Metabolic Encephalopathies

PART V
Congenital Structural Defects
24 Overview of Human BrainMalformations
25 Disorders of Neural Tube Development
26 Disorders of Forebrain Development
27 Disorders of Cerebellar and Brainstem Development
28 Disorders of Brain Size
29 Malformations of Cortical Development
30 Hydrocephalus and Arachnoid Cysts
31 Congenital Anomalies of the Skull
32 Developmental Encephalopathies
33 Prenatal Diagnosis of Structural Brain Anomalies

PART VI
Genetic, Metabolic and Neurocutaneous Disorders

34 Neurogenetics in the Genome Era
35 Chromosomes and Chromosomal Abnormalities
36 Approach to the Patient with a Metabolic Disorder
37 Aminoacidemias and Organic Acidemias
38 Inborn Errors of Urea Synthesis
39 Diseases Associated with Primary Abnormalities in Carbohydrate Metabolism
40 Disorders of Glycosylation
41 Lysosomal Storage Diseases
42 Mitochondrial Diseases
43 Peroxisomal Disorders
44 Neurotransmitter-Related Disorders
45 Phakomatoses and Allied Conditions
46 Disorders of Vitamin Metabolism
47 Nutrition and the Developing Brain
48 The Neuronal Ceroid Lipofuscinosis Disorders
49 Channelopathies

PART VII
Neurodevelopmental Disorders
50 Neurodevelopmental Disabilities: Conceptual Framework
51 Global Developmental Delay and Intellectual Disability
52 Cognitive and Motor Regression
53 Developmental Language Disorders
54 Nonverbal Learning Disabilities and Associated Disorders
55 Dyslexia
56 Attention Deficit–Hyperactivity Disorder
57 Autistic Spectrum Disorders
58 Management of Common Comorbidities Associated with Neurodevelopmental Disorders
59 Treatment of Neurodevelopmental Disorders
60 Neuropsychopharmacology

PART VIII
Epilepsy

61 Overview of Seizures and Epilepsy in Children
62 Principles of Management and Outcome
63 Neurophysiology of Seizures and Epilepsy
64 Epilepsy Genetics
65 Febrile Seizures
66 Generalized Seizures
67 Focal and Multifocal Seizures
68 Epileptic Spasms and Myoclonic Seizures
69 Status Epilepticus
70 Electroclinical Syndromes: Neonatal Onset
71 Electroclinical Syndromes: Infantile Onset
72 Electroclinical Syndromes: Childhood Onset
73 Electroclinical Syndromes: Adolescent Onset
Video 73.1 Focal Seizure with Dyscognitive Features
74 Focal Structural Epilepsy
75 Other Acquired Epilepsies: Trauma, Stroke, Tumors
76 Inherited Metabolic Epilepsies
77 Antiseizure Drug Therapy in Children
78 Epilepsy Surgery in the Pediatric Population
79 Neuromodulation in Epilepsy
80 Ketogenic Diets
81 Pediatric Psychogenic Nonepileptic Seizures and Psychiatric Disorders
82 Behavioral, Cognitive, and Social Aspects of Childhood Epilepsy
83 Mortality in Children with Epilepsy

PART IX
Nonepileptiform Paroxysmal Disorders and Disorders of Sleep
84 Headache in Children and Adolescents
85 Breath-Holding Spells and Reflex Anoxic Seizures
86 Syncope and Postural Orthostatic Tachycardia Syndrome
87 Nocturnal Paroxysmal Disorders
88 Disorders of Excessive Sleepiness
89 Restless Legs Syndrome and Periodic Limb Movement Disorder in Children and Adolescents
90 Apparent Life-Threatening Event and Sudden Infant Death Syndrome

PART X
Disorders of Balance and Movement
91 The Cerebellum and the Hereditary Ataxias
92 Acute Cerebellar Ataxia
Video 92.1 Signs of Ataxia
93 Movement Disorders: An Overview
94 Paroxysmal Dyskinesias
95 Movement Disorders of Infancy
96 Drug-Induced Movement Disorders in Children
97 Cerebral Palsy
98 Tics and Tourette Syndrome

PART XI
White Matter Disorders
99 Genetic and Metabolic Disorders of the White Matter
100 Acquired Disorders Affecting the White Matter

PART XII
Brain Injury and Disorders of Consciousness
101 Disorders of Consciousness in Children
102 Traumatic Brain Injury in Children
103 Abusive Head Trauma
104 Hypoxic-Ischemic Encephalopathy in Infants and Older Children
105 Disorders of Intracranial Pressure
106 Spinal Cord Injury
107 Determination of Brain Death in Infants and Children

PART XIII
Cerebrovascular Disease in Children

108 Development and Function of the Cerebrovascular System
109 Arterial Ischemic Stroke in Infants and Children
110 Sinovenous Thrombosis in Infants and Children
111 Vascular Malformations, Intracerebral Hemorrhage, and Subarachnoid Hemorrhage in Infants and Children
112 Cerebral Arteriopathies in Children
113 Coagulation Disorders and Cerebrovascular Disease in Children

PART XIV
Infections of the Nervous System

114 Bacterial Infections of the Nervous System
115 Viral Infections of the Nervous System
116 Fungal, Rickettsial, and Parasitic Diseases of the Nervous System
117 Neurologic Complications of Immunization

PART XV
Immune Mediated Disorders of the Nervous System

118 Paraneoplastic Neurologic Syndromes
119 Immune-Mediated Epilepsy, Movement Disorders, and Hashimoto’s Encephalopathy in Children
120 Opsoclonus Myoclonus Syndrome
Video 120.1 OMS Evaluation Scale
121 Neurologic Manifestations of Rheumatic Disorders of Childhood

PART XVI
Pediatric Neurooncology

122 Pediatric Neuro-oncology: An Overview
123 Medulloblastoma
124 Other Embryonal and Pineal Malignancies of the Central Nervous System
125 Ependymoma
126 Pediatric Brain Tumors – High-Grade Glioma
127 Pediatric Low-Grade Glioma
128 Diffuse Intrinsic Pontine Glioma
129 Atypical Teratoid/Rhabdoid Tumors
130 Central Nervous System Germinoma and Other Germ Cell Tumors
131 Craniopharyngioma, Meningiomas, and Schwannomas
132 Pediatric Intradural Spinal Cord Tumors
133 System Cancer and the Central Nervous System Involvement
134 Posttreatment Neurologic Sequelae of Pediatric Central Nervous System Tumors

PART XVII
Neuromuscular Disorders

135 Muscle and Nerve Development in Health and Disease
136 Laboratory Assessment of the Child with Suspected Neuromuscular Disorders
137 Clinical Assessment of Pediatric Neuromuscular Disorders
138 The Floppy Infant
139 Genetic Disorders Affecting the Motor Neuron: Spinal Muscular Atrophy
140 Other Motor Neuron Diseases of Childhood
141 Genetic Peripheral Neuropathies
142 Acquired Peripheral Neuropathies
143 Inflammatory Neuropathies
144 Congenital Myasthenic Syndromes
145 Acquired Disorders of the Neuromuscular Junction
146 Duchenne and Becker Muscular Dystrophies
147 Congenital, Limb Girdle and Other Muscular Dystrophies
148 Congenital Myopathies
149 Metabolic Myopathies
150 Inflammatory Myopathies
151 Channelopathies: Myotonic Disorders and Periodic Paralysis
152 Management of Children with Neuromuscular Disorders

PART XVIII
Systemic and Autonomic Nervous

153 Endocrine Disorders of the Hypothalamus and Pituitary in Childhood and Adolescence
154 Disorders of the Autonomic Nervous System: Autonomic Dysfunction in Pediatric Practice
155 Disorders of Micturition and Defecation
156 Poisoning and Drug-Induced Neurologic Diseases
157 Neurologic Disorders in Children with Heart Disease
158 Neurologic Disorders Associated with Renal Diseases
159 Neurologic Disorders Associated with Gastrointestinal Diseases

PART XIX
Care of the Child with Neurologic Disorders
160 Counseling Children with Neurologic Disorders and Their Families
161 Approaches to Personalized Medicine in Pediatric Neurology
162 Pediatric Neurorehabilitation Medicine
163 Pain Management and Palliative Care
164 Ethical Issues in Child Neurology
165 Transitional Care for Children with Neurologic Disorders
166 Practice Guidelines in Pediatric Neurology
167 Special Education Law as it Relates to Children with Neurologic Disorders
168 Measurement of Health Outcomes in Pediatric Neurologic Disorders
169 The Influence of Computer Resources on Child Neurology
170 Education and Training of Child Neurologists and Workforce Issues
APPENDIX A
APPENDIX B
Index

Details

No. of pages:
2969
Language:
English
Copyright:
© Elsevier 2018
Published:
Imprint:
Elsevier
eBook ISBN:
9780323374811
eBook ISBN:
9780323374828

About the Author

Kenneth Swaiman

Affiliations and Expertise

Director Emeritus, Division of Pediatric Neurology, Professor Emeritus of Neurology and Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota

Stephen Ashwal

Affiliations and Expertise

Distinguished Professor of Pediatrics, Chief of the Division of Child Neurology and Pediatrics, Loma Linda University School of Medicine, Loma Linda, California

Donna Ferriero

Affiliations and Expertise

W.H. and Marie Wattis Distinguished Professor and Chair, Department of Pediatrics, Physician-in-Chief, USCF Benioff Children's Hospital, University of California, San Francisco, California

Nina Schor

Affiliations and Expertise

William H. Eilinger Professor and Chair, Department of Pediatrics, Professor, Department of Neurology, Pediatrician-in-Chief, Golisano Children’s Hospital, University of Rochester Medical Center, Rochester, New York

Richard Finkel

Andrea Gropman

Affiliations and Expertise

Chief, Neurogenetics and Neurodevelopmental Disabilities, Department of Neurology, Children’s National Medical Center and the George Washington University of the Health Sciences, Washington, D.C.

Phillip Pearl

Affiliations and Expertise

Director of Epilepsy and Clinical Neurophysiology, William G. Lennox Chair and Professor of Neurology, Harvard Medical School