Swaiman's Pediatric Neurology

Principles and Practice

6th Edition - September 2, 2014
Authors: Kenneth F. Swaiman, Stephen Ashwal, Donna M Ferriero, Nina F Schor, Richard S. Finkel, Andrea L. Gropman, Phillip L Pearl, Michael Shevell
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 3 7 1 0 1 - 8

Since 1975, Dr. Kenneth Swaiman’s classic text has been the reference of choice for authoritative guidance in pediatric neurology, and the 6th Edition continues this tradition o… Read more

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Since 1975, Dr. Kenneth Swaiman’s classic text has been the reference of choice for authoritative guidance in pediatric neurology, and the 6th Edition continues this tradition of excellence with thorough revisions that bring you fully up to date with all that’s new in the field. Five new sections, 62 new chapters, 4 new editors, and a reconfigured format make this a comprehensive and clearly-written resource for the experienced clinician as well as the physician-in-training.

PART I
Clinical Evaluation

1 General Aspects of the Patient’s Neurologic History

2 Neurologic Examination of the Older Child

3 Neurologic Examination after the Newborn Period Until 2 Years of Age

4 Neurologic Examination of the Term and Preterm Infant

5 Muscular Tone and Gait Disturbances

6 Vision Loss

7 Hearing Impairment

8 Vertigo

9 Taste and Smell

10 Neuropsychological Assessment

PART II
Neurodiagnostic Testing

11 Spinal Fluid Examination

12 Pediatric Neuroimaging

13 Pediatric Neurophysiologic Evaluation

PART III
Emerging Neuroscience Concepts

14 Microstructural and Functional Connectivity in the Developing Brain

15 Stem Cell Transplantation for Childhood Neurologic Disorders

16 Cellular and Animal Models of Neurologic Disease

PART IV
Perinatal Acquired and Congenital Neurologic Disorders

17 Neonatal Neurointensive Care

18 Neonatal Seizures

19 Hypoxic-Ischemic Brain Injury in the Term Newborn

20 Cerebrovascular Disorders in the Newborn

21 Neonatal Nervous System Trauma

22 Injury to the Developing Preterm Brain: Intraventricular Hemorrhage and White Matter Injury
Video 22.1 Endoscopic View of Clot at the Foramen of Monro
Video 22.2 Endoscopic Third Ventriculostomy in an Infant with Posthemorrhagic Hydrocephalus

23 Perinatal Metabolic Encephalopathies

PART V
Congenital Structural Defects

24 Overview of Human BrainMalformations

25 Disorders of Neural Tube Development

26 Disorders of Forebrain Development

27 Disorders of Cerebellar and Brainstem Development

28 Disorders of Brain Size

29 Malformations of Cortical Development

30 Hydrocephalus and Arachnoid Cysts

31 Congenital Anomalies of the Skull

32 Developmental Encephalopathies

33 Prenatal Diagnosis of Structural Brain Anomalies

PART VI
Genetic, Metabolic and Neurocutaneous Disorders

34 Neurogenetics in the Genome Era

35 Chromosomes and Chromosomal Abnormalities

36 Approach to the Patient with a Metabolic Disorder

37 Aminoacidemias and Organic Acidemias

38 Inborn Errors of Urea Synthesis

39 Diseases Associated with Primary Abnormalities in Carbohydrate Metabolism

40 Disorders of Glycosylation

41 Lysosomal Storage Diseases

42 Mitochondrial Diseases

43 Peroxisomal Disorders

44 Neurotransmitter-Related Disorders

45 Phakomatoses and Allied Conditions

46 Disorders of Vitamin Metabolism

47 Nutrition and the Developing Brain

48 The Neuronal Ceroid Lipofuscinosis Disorders

49 Channelopathies

PART VII
Neurodevelopmental Disorders

50 Neurodevelopmental Disabilities: Conceptual Framework

51 Global Developmental Delay and Intellectual Disability

52 Cognitive and Motor Regression

53 Developmental Language Disorders

54 Nonverbal Learning Disabilities and Associated Disorders

55 Dyslexia

56 Attention Deficit–Hyperactivity Disorder

57 Autistic Spectrum Disorders

58 Management of Common Comorbidities Associated with Neurodevelopmental Disorders

59 Treatment of Neurodevelopmental Disorders

60 Neuropsychopharmacology

PART VIII
Epilepsy

61 Overview of Seizures and Epilepsy in Children

62 Principles of Management and Outcome

63 Neurophysiology of Seizures and Epilepsy

64 Epilepsy Genetics

65 Febrile Seizures

66 Generalized Seizures

67 Focal and Multifocal Seizures

68 Epileptic Spasms and Myoclonic Seizures

69 Status Epilepticus

70 Electroclinical Syndromes: Neonatal Onset

71 Electroclinical Syndromes: Infantile Onset

72 Electroclinical Syndromes: Childhood Onset

73 Electroclinical Syndromes: Adolescent Onset
Video 73.1 Focal Seizure with Dyscognitive Features

74 Focal Structural Epilepsy

75 Other Acquired Epilepsies: Trauma, Stroke, Tumors

76 Inherited Metabolic Epilepsies

77 Antiseizure Drug Therapy in Children

78 Epilepsy Surgery in the Pediatric Population

79 Neuromodulation in Epilepsy

80 Ketogenic Diets

81 Pediatric Psychogenic Nonepileptic Seizures and Psychiatric Disorders

82 Behavioral, Cognitive, and Social Aspects of Childhood Epilepsy

83 Mortality in Children with Epilepsy

PART IX
Nonepileptiform Paroxysmal Disorders and Disorders of Sleep

84 Headache in Children and Adolescents

85 Breath-Holding Spells and Reflex Anoxic Seizures

86 Syncope and Postural Orthostatic Tachycardia Syndrome

87 Nocturnal Paroxysmal Disorders

88 Disorders of Excessive Sleepiness

89 Restless Legs Syndrome and Periodic Limb Movement Disorder in Children and Adolescents

90 Apparent Life-Threatening Event and Sudden Infant Death Syndrome

PART X
Disorders of Balance and Movement

91 The Cerebellum and the Hereditary Ataxias

92 Acute Cerebellar Ataxia
Video 92.1 Signs of Ataxia

93 Movement Disorders: An Overview

94 Paroxysmal Dyskinesias

95 Movement Disorders of Infancy

96 Drug-Induced Movement Disorders in Children

97 Cerebral Palsy

98 Tics and Tourette Syndrome

PART XI
White Matter Disorders

99 Genetic and Metabolic Disorders of the White Matter

100 Acquired Disorders Affecting the White Matter

PART XII
Brain Injury and Disorders of Consciousness

101 Disorders of Consciousness in Children

102 Traumatic Brain Injury in Children

103 Abusive Head Trauma

104 Hypoxic-Ischemic Encephalopathy in Infants and Older Children

105 Disorders of Intracranial Pressure

106 Spinal Cord Injury

107 Determination of Brain Death in Infants and Children

PART XIII
Cerebrovascular Disease in Children

108 Development and Function of the Cerebrovascular System

109 Arterial Ischemic Stroke in Infants and Children

110 Sinovenous Thrombosis in Infants and Children

111 Vascular Malformations, Intracerebral Hemorrhage, and Subarachnoid Hemorrhage in Infants and Children

112 Cerebral Arteriopathies in Children

113 Coagulation Disorders and Cerebrovascular Disease in Children

PART XIV
Infections of the Nervous System

114 Bacterial Infections of the Nervous System

115 Viral Infections of the Nervous System

116 Fungal, Rickettsial, and Parasitic Diseases of the Nervous System

117 Neurologic Complications of Immunization

PART XV
Immune Mediated Disorders of the Nervous System

118 Paraneoplastic Neurologic Syndromes

119 Immune-Mediated Epilepsy, Movement Disorders, and Hashimoto’s Encephalopathy in Children

120 Opsoclonus Myoclonus Syndrome
Video 120.1 OMS Evaluation Scale

121 Neurologic Manifestations of Rheumatic Disorders of Childhood

PART XVI
Pediatric Neurooncology

122 Pediatric Neuro-oncology: An Overview

123 Medulloblastoma

124 Other Embryonal and Pineal Malignancies of the Central Nervous System

125 Ependymoma

126 Pediatric Brain Tumors – High-Grade Glioma

127 Pediatric Low-Grade Glioma

128 Diffuse Intrinsic Pontine Glioma

129 Atypical Teratoid/Rhabdoid Tumors

130 Central Nervous System Germinoma and Other Germ Cell Tumors

131 Craniopharyngioma, Meningiomas, and Schwannomas

132 Pediatric Intradural Spinal Cord Tumors

133 System Cancer and the Central Nervous System Involvement

134 Posttreatment Neurologic Sequelae of Pediatric Central Nervous System Tumors

PART XVII
Neuromuscular Disorders

135 Muscle and Nerve Development in Health and Disease

136 Laboratory Assessment of the Child with Suspected Neuromuscular Disorders

137 Clinical Assessment of Pediatric Neuromuscular Disorders

138 The Floppy Infant

139 Genetic Disorders Affecting the Motor Neuron: Spinal Muscular Atrophy

140 Other Motor Neuron Diseases of Childhood

141 Genetic Peripheral Neuropathies

142 Acquired Peripheral Neuropathies

143 Inflammatory Neuropathies

144 Congenital Myasthenic Syndromes

145 Acquired Disorders of the Neuromuscular Junction

146 Duchenne and Becker Muscular Dystrophies

147 Congenital, Limb Girdle and Other Muscular Dystrophies

148 Congenital Myopathies

149 Metabolic Myopathies

150 Inflammatory Myopathies

151 Channelopathies: Myotonic Disorders and Periodic Paralysis

152 Management of Children with Neuromuscular Disorders

PART XVIII
Systemic and Autonomic Nervous

153 Endocrine Disorders of the Hypothalamus and Pituitary in Childhood and Adolescence

154 Disorders of the Autonomic Nervous System: Autonomic Dysfunction in Pediatric Practice

155 Disorders of Micturition and Defecation

156 Poisoning and Drug-Induced Neurologic Diseases

157 Neurologic Disorders in Children with Heart Disease

158 Neurologic Disorders Associated with Renal Diseases

159 Neurologic Disorders Associated with Gastrointestinal Diseases

PART XIX
Care of the Child with Neurologic Disorders

160 Counseling Children with Neurologic Disorders and Their Families

161 Approaches to Personalized Medicine in Pediatric Neurology

162 Pediatric Neurorehabilitation Medicine

163 Pain Management and Palliative Care

164 Ethical Issues in Child Neurology

165 Transitional Care for Children with Neurologic Disorders

166 Practice Guidelines in Pediatric Neurology

167 Special Education Law as it Relates to Children with Neurologic Disorders

168 Measurement of Health Outcomes in Pediatric Neurologic Disorders

169 The Influence of Computer Resources on Child Neurology

170 Education and Training of Child Neurologists and Workforce Issues
APPENDIX A
APPENDIX B
Index

Kenneth F. Swaiman

Affiliations and expertise

Director Emeritus, Division of Pediatric Neurology, Professor Emeritus of Neurology and Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota

Stephen Ashwal

Dr. Stephen Ashwal is Distinguished Professor and former Chief of the Division of Child Neurology in the Department of Pediatrics at Loma Linda University School of Medicine. He is a graduate of New York University School of Medicine (1966-70), and completed his residency training programs in Pediatrics (Bellevue Hospital, 70-73) and in Child Neurology (University of Minnesota, 73-76). His research activities have focused on critical care issues in child neurology related to brain death, the vegetative and minimally conscious states, bacterial meningitis, and near drowning; the role of nitric oxide in focal cerebral ischemia; development of animal models of neonatal stroke and the use of proton spectroscopy for outcome prediction after acute CNS injuries. He has been a member of the Child Neurology Society since 1975 and served as chair of the Scientific Selection, Ethics, Archives and Practice Committee, Councilor from the West, Secretary-Treasurer of the Society, and President (2001-03). Dr. Ashwal edited The Founders of Child Neurology, published on behalf of the Society in 1990, that is a history of the field of child neurology and its major contributors. He served as co-chair (representing the CNS) on The Multi-Society Task Force on the Persistent Vegetative State. He has been active in the development of practice guidelines related to child neurology and served as a member of the Guidelines Development Dissemination, and Implementation Subcommittee of the American Academy of Neurology that is responsible for development of guidelines dealing with issues related to the evaluation of children with autism, cerebral palsy, developmental delay, headaches and status epilepticus. With Dr. Kenneth Swaiman and six other co-editors, he served as co-editor of one of the main textbooks in the field of child neurology, Swaiman's Pediatric Neurology: Principles & Practice (2006, 2011, 2017).

Affiliations and expertise

Distinguished Professor of Pediatrics, Former Chief of the Division of Child Neurology and Pediatrics, Loma Linda University School of Medicine, Loma Linda, California, USA

Donna M Ferriero

Affiliations and expertise

W.H. and Marie Wattis Distinguished Professor and Chair, Department of Pediatrics, Physician-in-Chief, USCF Benioff Children's Hospital, University of California, San Francisco, California

Nina F Schor

Affiliations and expertise

William H. Eilinger Professor and Chair, Department of Pediatrics, Professor, Department of Neurology, Pediatrician-in-Chief, Golisano Children’s Hospital, University of Rochester Medical Center, Rochester, New York

Richard S. Finkel

Affiliations and expertise

Director, Experimental Neuroscience Program, St. Jude’s Children’s Research Hospital

Andrea L. Gropman

Affiliations and expertise

Chief, Neurogenetics and Neurodevelopmental Disabilities, Department of Neurology, Children’s National Medical Center and the George Washington University of the Health Sciences, Washington, D.C.

Phillip L Pearl

Affiliations and expertise

Director of Epilepsy and Clinical Neurophysiology, William G. Lennox Chair and Professor of Neurology, Harvard Medical School, Boston, Massachusetts

Michael Shevell

Affiliations and expertise

Chair, McGill Department of Pediatrics, Pediatrician-in-Chief, Montreal Children's Hospital-McGill University Health Centre (MUHC), Harvey Guyda Professor, Montreal, Quebec, Canada