Surface Activity in Drug Action - 1st Edition - ISBN: 9780444517159, 9780080456119

Surface Activity in Drug Action, Volume 21

1st Edition

Series Volume Editors: R.C. Srivastava A.N. Nagappa
eBook ISBN: 9780080456119
Hardcover ISBN: 9780444517159
Imprint: Elsevier Science
Published Date: 1st March 2005
Page Count: 340
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Table of Contents

Chapter 1. Introduction and scope

  1. Introduction

Chapter 2. Surface activity of drugs
2.1. Analgesics

2.2. Antimicorbials

2.3. Drugs acting on autonomic nervous system
2.4. Antihistamines

2.5. Drugs affecting renal and cardiovascular function

2.6. Drugs acting on central nervous system

2.7. Miscellaneous

Chapter 3. Theories of drug action
3.1. Commonly used terms

3.2. Theories of drug action

3.3. Occupancy theory

Chapter 4. The liquid membrane hypothesis of drug action

4.1. The liquid membrane hypothesis
4.2. The liquid membrane hypothesis of drug action

Chapter 5. Liquid membranes as biomimetic system
5.1. Introduction

5.2. Liquid membranes from cholesterol, lecithin and lecithin-cholesterol mixtures

5.3. Mimicking light-induced transport

5.4. Hydrophilic Pathways

5.5. Mimicking electrical excitability of liquid membrane bilayers

Chapter 6. Role of liquid membranes in drug action-experimental studies
6.1. The design of experiments

6.2. Experimental studies

Chapter 7. Assessment of the Hypothesis
7.1. Implications of the hypothesis

7.2. The liquid membrane hypothesis vis-a-vis existing-theories of drug actions

Chapter 8. Application of surface activity in therapeutics

8.1. Drug Absorption

8.2. Solublizing agents

8.3. Dissolution

8.4. Drug stabilization

8.5. Surfactants in drug targeting

8.6. Surfactants as wetting agents

8.7. Synergistic effects

8.8. Prodrugs

8.9. Surfactants and drug delivery

8.10.Miscellaneous


Description

Surface activity is present in living systems; for example in body fluid or cell soup and molecules of surface-active nature are crucial to living matter and its organization. Surface Activity in Drug Action proposes "a liquid membrane hypothesis of drug action" for surface-active drugs. Chapters 1-7 contains an account of the hypothesis and chapter 8 contains a general account of the application of surface activity in therapeutics. The methodology and presentation of the information makes Surface Activity in Drug Action valuable reading for students and researchers interested in surface activity.

Key Features

  • Is clearly written
  • Includes contributions from prominent names in the field, such as Bhise and Subrahmanyam
  • Contains a general account of the application of surface activity in therapeutics

Readership

Graduate students, scientists and researchers working in biological chemistry


Details

No. of pages:
340
Language:
English
Copyright:
© Elsevier Science 2005
Published:
Imprint:
Elsevier Science
eBook ISBN:
9780080456119
Hardcover ISBN:
9780444517159

About the Series Volume Editors

R.C. Srivastava Series Volume Editor

Affiliations and Expertise

Birla Institute of Technology and Science, Pilani, India

A.N. Nagappa Series Volume Editor

Affiliations and Expertise

Birla Institute of Technology and Science, Pilani, India