Surface Activity in Drug Action
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Surface Activity in Drug Action

1st Edition - March 1, 2005

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  • Editors: R.C. Srivastava, A.N. Nagappa
  • eBook ISBN: 9780080456119

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Description

Surface activity is present in living systems; for example in body fluid or cell soup and molecules of surface-active nature are crucial to living matter and its organization. Surface Activity in Drug Action proposes "a liquid membrane hypothesis of drug action" for surface-active drugs. Chapters 1-7 contains an account of the hypothesis and chapter 8 contains a general account of the application of surface activity in therapeutics. The methodology and presentation of the information makes Surface Activity in Drug Action valuable reading for students and researchers interested in surface activity.

Key Features

* Is clearly written
* Includes contributions from prominent names in the field, such as Bhise and Subrahmanyam
* Contains a general account of the application of surface activity in therapeutics

Readership

Graduate students, scientists and researchers working in biological chemistry

Table of Contents

  • Chapter 1. Introduction and scope

    1. Introduction



    Chapter 2. Surface activity of drugs

    2.1. Analgesics

    2.2. Antimicorbials

    2.3. Drugs acting on autonomic nervous system

    2.4. Antihistamines

    2.5. Drugs affecting renal and cardiovascular function

    2.6. Drugs acting on central nervous system

    2.7. Miscellaneous



    Chapter 3. Theories of drug action

    3.1. Commonly used terms

    3.2. Theories of drug action

    3.3. Occupancy theory



    Chapter 4. The liquid membrane hypothesis of drug action

    4.1. The liquid membrane hypothesis

    4.2. The liquid membrane hypothesis of drug action



    Chapter 5. Liquid membranes as biomimetic system

    5.1. Introduction

    5.2. Liquid membranes from cholesterol, lecithin
    and lecithin-cholesterol mixtures

    5.3. Mimicking light-induced transport

    5.4. Hydrophilic Pathways

    5.5. Mimicking electrical excitability of liquid membrane bilayers



    Chapter 6. Role of liquid membranes in drug action-experimental studies

    6.1. The design of experiments

    6.2. Experimental studies


    Chapter 7. Assessment of the Hypothesis

    7.1. Implications of the hypothesis

    7.2. The liquid membrane hypothesis vis-a-vis existing-theories of drug actions



    Chapter 8. Application of surface activity in therapeutics

    8.1. Drug Absorption

    8.2. Solublizing agents

    8.3. Dissolution

    8.4. Drug stabilization

    8.5. Surfactants in drug targeting

    8.6. Surfactants as wetting agents

    8.7. Synergistic effects

    8.8. Prodrugs

    8.9. Surfactants and drug delivery

    8.10.Miscellaneous

Product details

  • No. of pages: 340
  • Language: English
  • Copyright: © Elsevier Science 2005
  • Published: March 1, 2005
  • Imprint: Elsevier Science
  • eBook ISBN: 9780080456119

About the Series Volume Editors

R.C. Srivastava

Affiliations and Expertise

Birla Institute of Technology and Science, Pilani, India

A.N. Nagappa

Affiliations and Expertise

Birla Institute of Technology and Science, Pilani, India

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