Studies in Natural Products Chemistry - 1st Edition - ISBN: 9780444595140, 9780444595157

Studies in Natural Products Chemistry, Volume 37

1st Edition

Editors: Atta-ur- Rahman
eBook ISBN: 9780444595157
Hardcover ISBN: 9780444595140
Imprint: Elsevier
Published Date: 30th July 2012
Page Count: 438
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Table of Contents



Studies in Natural Products Chemistry

Chapter 1 Botanical Medicines for Diuresis






Chapter 2 The Artemisia L. Genus


Ethnopharmacological Uses of Artemisia Species

Sesquiterpene Lactones from Artemisia Genus

Pharmacological Activity of Artemisia Genus

Anti-inflammatory and Immunosuppressive Activities

Antitumour Activity


Chapter 3 Secondary Metabolites with Antinematodal Activity from Higher Plants





Furans and Tetrahydrofurans




Phenols and Phenolic Acids

Phenylpropanoids and Lignans





Isothiocyanates and Glucosinolates

Cyanogenic Glycosides

Other Compounds

Concluding Remarks

Chapter 4 Beneficial Health Effects of Bioactive Compounds Present in Spices and Aromatic Herbs



Phenolics Acids



Chapter 5 Bioactive Plant Isoprenoids

Overview of Terpenoids

Menthol (Monoterpene)

Artemisinin (Sesquiterpene)

Taxol (Diterpene)

Ginsenosides (triterpenes)

Carotenoids (Tetraterpenes)


Chapter 6 Trypanocidal Monoterpenes


Structure–Activity Relationships for Trypanocidal Monoterpenes



Chapter 7 Plant and Fungi 3,4-Dihydroisocoumarins




Marine Source

Pharmacological and Biological Activity

DHIC from Animal Origin

Chapter 8 The Modern Analytical Determination of Botanicals and Similar Novel Natural Products by the HPTLC Fingerprint Approach


The HPTLC World

Case Studies


Chapter 9 Natural Antioxidants (NAO) of Plants Acting as Scavengers of Free Radicals


Oxidative Damage due to Photochemical Reaction: Formation of Singlet Oxygen (1O2)

Oxidative Damage due to Non-photochemical Reaction: Formation of Free Radicals and ROS


ROS and Free Radicals

Cellular Antioxidant Enzyme Systems

Natural Antioxidants (NAO) of Plants


Chapter 10 Bioactive Natural Products as Potential Candidates to Control Aedes aegypti, the Vector of Dengue


Natural Insecticides Derived from Plants

Natural Insecticides Derived from Fungi

Natural Insecticides Derived from Bacteria

Natural Insecticides Derived from Other Organisms

Biocontrol Agents

Bioassay Against Aedes aegypti Larvae



Subject Index


Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 37 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural products and medicinal chemistry.

Key Features

  • Describes the chemistry of bioactive natural products
  • Contains contributions by leading authorities in the field
  • A valuable source for researchers and engineers working in natural product and medicinal chemistry


Natural product chemists, medicinal chemists, pharmacologists as well as researchers in academia and the pharmaceutical industry


No. of pages:
© Elsevier 2012
eBook ISBN:
Hardcover ISBN:


"...each chapter is well-written and extensively referenced."--JOURNAL OF MEDICINAL CHEMISTRY
" a valuable collection of recent synthetic endeavors for organic chemists who find the strategy and execution of a total synthesis appealing and interesting."--JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
"... The chapters are well-written, have good, clear structures, and the final products reflect a characteristically well produced volume."-- INTERNATIONAL JOURNAL OF PHARMACOGNOSY
"...the chapters are impressively up-to-date, with many literature references."-- FITOTERAPIA

Ratings and Reviews

About the Editors

Atta-ur- Rahman Editor

Atta-ur-Rahman, FRS, D.Phil., TI, SI HI, NI, is a leading scientist and scholar in the field of organic chemistry from Pakistan, especially renowned for his research in the various areas relating to natural product chemistry. With over 909 publications in the field of his expertise including 116 books largely published by leading publishers in Europe and USA and 27 patents, he is also credited for reviving the higher education and research practices in Pakistan.

Prof. Rahman was elected as Fellow of Royal Society (London) in July 2006 thereby becoming one of the 4 scientists from the Muslim world to have ever won this honor in the last 350 years when the Royal Society was established. He is also the only scientist from the Muslim world to have been conferred the UNESCO Science Prize in 1999.[11] He has been conferred honorary doctorate degrees by many universities including the degree of Doctor of Science (Sc.D.) by Cambridge University (UK) (1987) and an Honorary degree of Doctor of Education by Coventry University UK in November 2007. He was elected Honorary Life Fellow of Kings College, Cambridge University, UK in 2007. Prof. Atta-ur-Rahman was conferred the TWAS Prize for Institution Building in Durban, South Africa in October 2009 in recognition of his contributions for bringing about revolutionary changes in the higher education sector in Pakistan. He was awarded the Engro Excellence Award in Science & Technology 2011 for meritorious contributions.

He is President of Network of Academies of Sciences of Islamic Countries (NASIC) and the Vice-President (Central & South Asia) of the Academy of Sciences for the Developing World (TWAS) Council, and Foreign Fellow of Korean Academy of Sciences. Prof. Atta-ur-Rahman was the President of the Pakistan Academy of Sciences (2003–06), and was again elected President of Pakistan Academy of Sciences in January 2011.

He was the Federal Minister for Science and Technology (14 March 2000 – 20 November 2002), Federal Minister of Education (2002) and Chairman of the Higher Education Commission with the status of a Federal Minister from 2002-2008. The Austrian government also honoured him with its highest civil award ("Das Große Goldene Ehrenzeichen am Bande", 2007) in recognition of his eminent contributions.

Prof. Atta-ur-Rahman was the Coordinator General of COMSTECH, an OIC Ministerial Committee comprising the 57 Ministers of Science & Technology from 57 OIC member countries during 1996-2012. He is also the Patron of International Centre of Chemical and Biological Sciences (which comprises a number of institutes, including the Hussain Ebrahim Jamal Research Institute of Chemistry and the Dr. Panjwani Center of Molecular Medicine and Drug Development) at Karachi University.

He established a research center on Genomics in Karachi University. In recognition of the eminent contributions of Prof. Atta-ur-Rahman, a number of institutions have been named after him within and outside Pakistan. These include a natural product chemistry institute (Atta-ur-Rahman Research Institute of Natural Product Discovery, RiND) at the University of Technology Mara in Malaysia, Atta-ur-Rahman School of Applied Biosciences at National University of Science & Technology in Islamabad, and Dr. Atta-ur-Rahman Building at the International Centre for Chemical and Biological Sciences, University of Karachi. The Academy of Sciences in the Developing World (TWAS) based in Trieste, Italy has introduced a Dr. Atta-ur-Rahman Prize in Chemistry to a scientist from the developing world each year. The Prize carries a cash award of $ 5,000 and a Certificate.

Affiliations and Expertise

University of Karachi, Pakistan