Natural Product Chemistry continues to expand to exciting new frontiers of great importance in medicine. Written by international authorities in various fields of natural product chemistry, this latest volume in the well-established series Studies in Natural Products Chemistry contains 23 chapters, covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases. This present volume, will again be of great interest to research scientists and scholars working in the exciting field of new drug discovery.

Key Features

* Written by international authorities in the various fields of natural product chemistry * Contains 23 comprehensive articles covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases * Valuable source of information for research scientists and scholars in the field of new drug discovery


Researchers in academia and industry involved in Natural Product Chemistry and Medicinal Chemistry

Table of Contents

Synthesis of immunosuppressant FR901483 and biogenetically related TAN1251 alkaloids (J. Bonjoch, F. Diaba).
Bioactive natural products from southern african marine invertebrates (M.T. Davies-Coleman).
Bioactive marine sesterterpenoids (S. de Rosa, M. Mitova).
Antimalarial lead compounds from marine organisms (E. Fattorusso, O. Taglialatela-Scafati).
Bioactive saponins with cancer related and immunomodulatory activity: Recent developments (M.-A. Lacaille-Dubois).
Chemical and biological aspects of iridoid bearing plants of temperate region (Neeraj Kumar et al.).
Iridoids and secoiridoids from Oleaceae (J.A. Pérez et al.).
Pharmacological activities of iridoids biosynthesized by route II (M. Gálvez et al.).
Chemistry and neurotrophic activity of seco-prezizaane- and anislactone-type sesquiterpenes from Illicium species (Yoshiyasu Fukuyama, Jian-Mei Huang).
New insights into the bioactivity of cucurbitacins (J. Luis Ríos et al.).
Griseofulvin and other biologically active halogen containing compounds from fungi (T. Řezanka, J. Spížek).
Bioactive alkaloids of fungal origin (Hideo Hayashi).
Chemistry and biological activities of naturally occurring phthalides (Ge Lin et al.).
Chemistry and biological activity of polyisoprenylated benzophenone derivatives (O. Cuesta-Rubio et al.).
The benzophenones: Isolation, structural elucidation and biological activities (S. Bag


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© 2005
Elsevier Science
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About the author

Atta-ur- Rahman

Atta-ur-Rahman, FRS, D.Phil., TI, SI HI, NI, is a leading scientist and scholar in the field of organic chemistry from Pakistan, especially renowned for his research in the various areas relating to natural product chemistry. With over 909 publications in the field of his expertise including 116 books largely published by leading publishers in Europe and USA and 27 patents, he is also credited for reviving the higher education and research practices in Pakistan. Prof. Rahman was elected as Fellow of Royal Society (London) in July 2006 thereby becoming one of the 4 scientists from the Muslim world to have ever won this honor in the last 350 years when the Royal Society was established. He is also the only scientist from the Muslim world to have been conferred the UNESCO Science Prize in 1999.[11] He has been conferred honorary doctorate degrees by many universities including the degree of Doctor of Science (Sc.D.) by Cambridge University (UK) (1987) and an Honorary degree of Doctor of Education by Coventry University UK in November 2007. He was elected Honorary Life Fellow of Kings College, Cambridge University, UK in 2007. Prof. Atta-ur-Rahman was conferred the TWAS Prize for Institution Building in Durban, South Africa in October 2009 in recognition of his contributions for bringing about revolutionary changes in the higher education sector in Pakistan. He was awarded the Engro Excellence Award in Science & Technology 2011 for meritorious contributions. He is President of Network of Academies of Sciences of Islamic Countries (NASIC) and the Vice-President (Central & South Asia) of the Academy of Sciences for the Developing World (TWAS) Council, and Foreign Fellow of Korean Academy of Sciences. Prof. Atta-ur-Rahman was the President of the Pakistan Academy of Sciences (2003–06), and was again elected President of Pakistan Academy of Sciences in January 2011. He was the Federal Minister for Science and Technology (14 March 2000 – 20 November 2002), Federal M