Synthetic Routes to the Oxahydrindene Subunit of the Avermectinmilbemycin Family of Antiparasitic Agents: A Review
A New Tandem Process and its Application to the Syntheses of Macrolide Antibiotics
Stereoselective Synthetic and Mechanistic Chemistry of Bicyclomycin
The Role of Isocyanides in the Synthesis of β-Lactam Antibiotics and Related Compounds
Synthesis of the 1β-Methylcarbapenem Key Intermediates
Chemical Studies of the Taxane Diterpenes
Recent Advances in the Synthesis of Tumor-Promoting Diterpenes
Hydroxylated Indolizidines and Their Synthesis
A Survey of Indolo [2,3-a] Carbazole Alkaloids and Related Natural Products
Synthetic Methodology For 2-Amino Alcohols of Biological Interest
Stereoselective Synthesis of Natural Products Via Cationic and Radical Intermediates
Studies in Natural Products Chemistry Volume 12: Stereoselective Synthesis (Part H) reviews the stereoselective synthetic and mechanistic chemistry of bicyclomycin. It discusses chemical studies of the taxane diterpenes; the synthetic methodology for 2-amino alcohols of biological interest; and the synthesis and structure of hydroxylated indolizidines.
Some of the topics covered in the book are the synthetic routes to the oxahydrindene subunit of the avermectin-milbemycin family of antiparasitic agents; isolation, structure elucidation, biosynthesis, and biological activity of the avermectins; two-stage coupling process of macrolide antibiotics synthesis; and synthesis of the rifamycin S ansa-chain compound. The complete synthesis of erythromycin A is also covered. The role of isocyanides in the synthesis of beta lactam antibiotics and the characteristics of the beta lactam antibiotics are discussed. The development of an A-Ring annulation strategy for taxane synthesis is also presented. A chapter is devoted to the advances in the synthesis of tumor-promoting diterpenes.
The book can provide useful information to chemists, biologists, students, and researchers.
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- © Elsevier 1993
- 3rd March 1993
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