Studies in Natural Products Chemistry - 1st Edition - ISBN: 9780444639318, 9780444639370

Studies in Natural Products Chemistry, Volume 52

1st Edition

Editors: Atta-ur-Rahman
eBook ISBN: 9780444639370
Hardcover ISBN: 9780444639318
Imprint: Elsevier
Published Date: 20th February 2017
Page Count: 514
Tax/VAT will be calculated at check-out Price includes VAT (GST)
25% off
25% off
25% off
25% off
25% off
20% off
20% off
25% off
25% off
25% off
25% off
25% off
20% off
20% off
30% off
30% off
30% off
30% off
30% off
20% off
20% off
295.00
221.25
221.25
221.25
221.25
221.25
236.00
236.00
262.00
196.50
196.50
196.50
196.50
196.50
209.60
209.60
205.00
143.50
143.50
143.50
143.50
143.50
164.00
164.00
Unavailable
Price includes VAT (GST)
× DRM-Free

Easy - Download and start reading immediately. There’s no activation process to access eBooks; all eBooks are fully searchable, and enabled for copying, pasting, and printing.

Flexible - Read on multiple operating systems and devices. Easily read eBooks on smart phones, computers, or any eBook readers, including Kindle.

Open - Buy once, receive and download all available eBook formats, including PDF, EPUB, and Mobi (for Kindle).

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Table of Contents

Chapter 1. Natural Environments for Nanoparticles Synthesis of Metal, Metal Oxides, Core–Shell and Bimetallic Systems

Introduction

Key Concepts of Biological Nanosynthesis, State of the Art

Biosynthesis of NPs by Bacteria

Biosynthesis of NPs by Fungi

Biosynthesis of NPs in Plant Extracts

Core@Shell and Mixed NPs

Mechanistic Concepts

Summary

Terms, Abbreviations, and Acronyms

Chapter 2. 2-Aminoimidazoles: Synthesis by Ring Transformation Reactions

Introduction

Synthesis of Aminoimidazoles From Aminooxazoles

Synthesis of Fused Aminoimidazoles From Aminooxazoles

Synthesis of Aminoimidazoles From Other Azoles

Synthesis of Aminoimidazoles From Imidazopyrimidines

Synthesis of Aminoimidazoles From Other Heterocycles

Conclusion

Chapter 3. Strategies for Total Synthesis of Furanocembranolides and Related Natural Products From Marine Organisms

Introduction

Synthesis of Acerosolide

Synthesis of Bipinnatin J

Synthesis of Rubifolide

Synthesis of Deoxypukalide

Further Synthetic Studies Toward Furanocembranolides

Furanocembranolid Derivatives and Related Compounds

Concluding Remarks

Chapter 4. Phyllobilins: A New Group of Bioactive Compounds

Introduction

Catabolism of Chlorophyll Pigments

The PaO/Phyllobilin Pathway

Regulation of the PaO/Phyllobilin Route

Structural Characteristics of the FCCs and DFCCs

Transport Into Vacuole and Isomerization to NCCs and DNCCs

Further Linear Chlorophyll Catabolites

Methods of Analysis of Phyllobilins

Extraction Procedures From Vegetal Tissues

Analytical and Semipreparative HPLC Methodologies

Structural Elucidation and Identification: Nuclear Magnetic Resonance

Structural Elucidation and Identification: Mass Spectrometry

Biological Properties of Phyllobilins

Chlorophyll Metabolism in Animals

Concluding Remarks

Abbreviations

Chapter 5. Artemisinin the Nobel Molecule: From Plant to Patient

Introduction

From the Plant: ART Biosynthesis

To the Patient

Conclusion

Abbreviations

Chapter 6. Bioactive Polyphenols for Diabetes and Inflammation in Psoriasis Disease

Introduction

Polyphenols From Forest Resources

Physiopathology of Diabetes Mellitus

Impact of Forest Biomass Polyphenols on Type 2 Diabetes Mellitus

Current Concepts of Psoriasis Pathogenesis

Natural Treatments for Psoriasis: Role of Forest Biomass Polyphenols

Research Perspective

Concluding Remarks

Abbreviation

Chapter 7. Nonhalogenated Heterotricyclic Sesquiterpenes From Marine Origin I: Fused Systems

Introduction

Fused Heterocyclic Sesquiterpenes

Conclusion

Abbreviations

Chapter 8. Phytochemicals With Antileishmanial Activity: Prospective Drug Targets

Introduction

Inhibition of Parasite Proteins as Prospective Drug Targets

Inhibition of Metabolic Pathway of Parasite as Prospective Drug Targets

Conclusion

Abbreviations

Chapter 9. Parthenolide and Parthenolide-Like Sesquiterpene Lactones as Multiple Targets Drugs: Current Knowledge and New Developments

Introduction

New Sources of Parthenolide

Pharmacology of Parthenolide

Synergistic Effects to Improving the Chemosensitivity to Parthenolide

Parthenolide Delivery

Pharmacology of Parthenolide-Like Sesquiterpene Lactones

Concluding Remarks

Abbreviations

Chapter 10. Alkaloids From Apocynaceae: Origin, Pharmacotherapeutic Properties, and Structure-Activity Studies

Introduction

Anticancer Activities of Apocynaceaeous Alkaloids

Neuroprotective and Psychoactive Activities of Apocynaceaeous Alkaloids

Biocidal Activities of Apocynaceaeous Alkaloids

Other Pharmacological Properties of Apocynaceaeous Alkaloids

Structure Activity Relationships

Derivatives and Synthetic Analogues

Concluding Remarks

Abbreviations


Description

Studies in Natural Products Chemistry covers the synthesis, testing, and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products.

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then rapidly determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development in the pharmaceutical industry.

Key Features

  • Focuses on the chemistry of bioactive natural products
  • Contains contributions by leading authorities in the field
  • Presents sources of new pharmacophores

Readership

Natural product chemists, medicinal chemists, pharmacologists as well as academic and industry researchers


Details

No. of pages:
514
Language:
English
Copyright:
© Elsevier 2017
Published:
Imprint:
Elsevier
eBook ISBN:
9780444639370
Hardcover ISBN:
9780444639318

About the Editors