Structure - 2nd Edition - ISBN: 9780121192013, 9780323161800


2nd Edition

Editors: Geoffrey Bourne
eBook ISBN: 9780323161800
Imprint: Academic Press
Published Date: 1st January 1972
Page Count: 392
Sales tax will be calculated at check-out Price includes VAT/GST
Price includes VAT/GST
× DRM-Free

Easy - Download and start reading immediately. There’s no activation process to access eBooks; all eBooks are fully searchable, and enabled for copying, pasting, and printing.

Flexible - Read on multiple operating systems and devices. Easily read eBooks on smart phones, computers, or any eBook readers, including Kindle.

Open - Buy once, receive and download all available eBook formats, including PDF, EPUB, and Mobi (for Kindle).

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.


The Biochemistry and Physiology of Bone, Second Edition: Volume I: Structure focuses on the nature and behavior of bone cells, the structure of the organic matrix of bone, mineral organization, and bone strength. It explores the histology of bone, the pathological calcification and radiation effects on bone, particularly, the morphology and cytochemistry as well as the functional significance of osteoblasts, the mode of action of the osteoclast, the ultrastructure of bone, and the mechanical engineering problems presented by bone. Organized into nine chapters, this edition begins with an overview of the general histology of bone, including tissues related to bone and its elementary constituents. It then discusses the origin of osteoblasts, the role of the osteoclast in the mechanism whereby calcium is unlocked from the skeleton under the influence of the parathyroid hormone, and the physiological and pathological effects of vitamins and hormones on skeletal tissue in vitro. It also explains the chemical composition of bone and the chemistry of bone collagen, the relationship between bone mineral and the organic matrix, the macromolecular organization of apatite and collagen, and the examinations of bone by scanning electron microscopy. The book concludes with a chapter on the shape, strength, and elasticity of bone. This book is a valuable source of information for anatomists, orthopedists, biochemists, cell biologists, physiologists, biomedical engineers, pathologists, clinicians, graduate students, professors, and others interested in the biochemical and physiological aspects of bone.

Table of Contents

List of Contributors Preface to Second Edition Preface to First Edition Contents of Other Volumes Chapter 1. General Histology of Bone I. Introduction II. Tissues Related to Bone III. Elementary Constituents of Bone IV. The Osteocytes V. Elementary Types of Bone VI. Higher Organization of Bone VII. Lamellation VIII. "Membrane" and "Cartilage" Bone and Bones IX. Evolution of Bone and Cartilage References Chapter 2. The Osteoblast I. Introduction II. General Morphology III. Cytochemistry IV. The Functional Significance of Osteoblasts V. Origin of Osteoblasts References Chapter 3. The Osteoclast I. Introduction II. Appearance III. Function IV. Mode of Action V. The Osteoclast and Parathyroid Hormone VI. Origin, Life-span, and Fate References Chapter 4. Skeletal Tissue in Culture I. Introduction II. Historical Aspects III. Techniques for the Growth of Skeletal Elements in Vitro IV. Metabolism of Skeletal Tissue in Vitro V. Physiological and Pathological Effects of Vitamins and Hormones on Skeletal Tissue in Vitro VI. Effects of Miscellaneous Substances on Skeletal Tissue in Vitro VII. Conclusions and Outlook References Chapter 5. The Organic Matrix of Bone I. Introduction II. The Chemical Composition of Bone III. The Chemistry of Bone Collagen IV. The Glycosaminoglycans (Acid Mucopolysaccharides) of Bone V. The Glycoproteins of Bone VI. The Lipids of Bone VII. The Peptides of Bone VIII. Molecular Interactions and Function References Chapter 6. The Ultrastructure of Bone I. Introduction II. The Organic Matrix of Bone III. The Bone Mineral IV. The Relationship between Mineral and Matrix V. The Bone Cells References Chapter 7. Aspects of the Molecular Structure of Bone I. Introduction I


No. of pages:
© Academic Press 1972
Academic Press
eBook ISBN:

About the Editor

Geoffrey Bourne

Ratings and Reviews