Structure, Function and Regulation of TOR complexes from Yeasts to Mammals

Structure, Function and Regulation of TOR complexes from Yeasts to Mammals

Part B

1st Edition - October 12, 2010

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  • Editors: Fuyuhiko Tamanoi, Michael Hall
  • Hardcover ISBN: 9780123810052
  • eBook ISBN: 9780123810069

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This volume of The Enzymes features high-caliber thematic articles on the topic of glycosylphosphatidylinositol (GPI) anchoring of proteins.

Key Features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field


Biochemists, cell biologists, molecular biologists, biophysicists.

Table of Contents

  • Chapter 1: Overview of GPI biosynthesis, gene list
    Taroh Kinoshita

    Chapter 2: GlcNAc transfer reaction, GPI-GnT, Ras signaling
    David E. Levin

    Chapter 3: GlcNAc-PI de-N-acetylase
    Michael A. J. Ferguson

    Chapter 4: Inositol acylation/deacylation
    Yoshifumi Jigami

    Chapter 5: Mannosylation
    Yusuke Maeda

    Chapter 6: Phosphoethanolamine transfer
    Peter Orlean

    Chapter 7: Transamidase
    Anant K. Menon

    Chapter 8: Flipping and pathway topology
    Anant Menon

    Chapter 9: Evolutional conservation and Bioinformatics
    John Samuelson

    Chapter 10: GPI in apicomplexan and parasites
    Ralph Schwarz

    Chapter 11: Chemical synthesis of GPI
    Ram A. Vishwakarma

    Chapter 12: Use of synthetic GPIs as anti-toxic vaccine
    Peter Seeberger

    Chapter 13: ER export and GPI-proteins
    Howard Riezman

    Chapter 14: Polarized sorting of GPI proteins
    Chiara Zurzolo

    Chapter 15: Involvement of GPIs in yeast cell wall structure
    Peter N. Lipke

    Chapter 16: Paroxysmal nocturnal hemoglobinuria (PIGA mutation)
    Lucio Luzzatto

    Chapter 17: Inherited GPI deficiency
    Anastasios Karadimitris

    Chapter 18: Inhibitors of GPI biosynthesis
    Terry K. Smith

Product details

  • No. of pages: 400
  • Language: English
  • Copyright: © Academic Press 2010
  • Published: October 12, 2010
  • Imprint: Academic Press
  • Hardcover ISBN: 9780123810052
  • eBook ISBN: 9780123810069

About the Serial Volume Editors

Fuyuhiko Tamanoi

Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997.

Affiliations and Expertise

Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, USA

Michael Hall

Affiliations and Expertise

Biozentrum, University of Basel, Switzerland

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