Structure and Function of Calcium Release Channels - 1st Edition - ISBN: 9780123810373, 9780123810380

Structure and Function of Calcium Release Channels, Volume 66

1st Edition

Editors: Irina Serysheva
eBook ISBN: 9780123810380
Hardcover ISBN: 9780123810373
Imprint: Academic Press
Published Date: 11th August 2010
Page Count: 372
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Table of Contents

PART 1: RyR Ca2+ Release channels

  1. RyRs: their disposition, frequency and relationships with other proteins of calcium release units (Clara Franzini Armstrong).
  2. Electron Microscopy of Ryanodine Receptors (Terrence Wagenknecht and Zheng Li).
  3. The ryanodine receptor pore: is there a consensus view? (Carney, J; Mason, SA; Viero, CL and Williams, AJ)
  4. Regulation of the RyR channel gating by different modulators (Derek Laver).
  5. Regulation of Ryanodine Receptor Ion Channels through Post-translational Modifications. (Gerhard Meissner).
  6. Crosstalk via the sarcoplasmic gap: The DHPR - RyR interaction (Manfred Grabner and Anamika Dayal).
  7. Ryanodinopathies: RyR-linked Muscle Diseases (Lan Wei and Robert T. Dirksen).
  8. PART 2: IP3R Ca2+ Release channels

  9. Structure of IP3 Receptors. (Irina I. Serysheva and Steven J. Ludtke)
  10. Molecular Architecture Of The Inositol 1,4,5-trisphosphate Receptor Pore. (Darren Boehninng)
  11. Adenophostins: high-affinity agonists of IP3 receptors. (Ana M. Rossi, Andrew, M. Riley, Barry V. L. Potter and Colin W. Taylor)
  12. Regulation of IP3R channel gating by Ca2+ and Ca2+ Binding Proteins (J. Kevin Foskett and Don-On Daniel Mak).
  13. Regulation of IP3R channels through phosphorylation/ATP (Matthew J. Betzenhauser and David I. Yule).
  14. Role of thiols in the structure and function of Inositol trisphosphate receptors (Suresh Joseph).
  15. Inositol 1,4,5-tripshosphate receptor, calcium signaling and polyglutamine expansion disorders (Ilya Bezprozvanny).


This volume of Current Topics in Membranes focuses on Membrane Protein Crystallization, beginning with a review of past successes and general trends, then further discussing challenges of mebranes protein crystallization, cell free production of membrane proteins and novel lipids for membrane protein crystallization.

This publication also includes tools to enchance membrane protein crystallization, technique advancements, and crystallization strategies used for photosystem I and its complexes, establishing Membrane Protein Crystallization as a needed, practical reference for researchers.


Membrane Protein Crystallization, a volume of the established Current Topics in Membranes serial. This volume is edited by Dr. Larry DeLucas, University of Alabama at Birmingham.


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About the Editors

Irina Serysheva Editor