The ongoing process of bio-evolution has produced materials which are perfectly adapted to fulfil a specific functional role. The natural world provides us with a multitude of examples of materials with durability, strength, mechanisms of programmed self-assembly and biodegradability.
The materials industry has sought to observe and appreciate the relationship between structure, properties and function of these biological materials. A multidisciplinary approach, building on recent advances at the forefront of physics, chemistry and molecular biology, has been successful in producing many synthetic structures with interesting and useful properties.
Structural Biological Materials: Design and Structure-Property Relationships represents an invaluable reference in the field of biological materials science and provides an incisive view into this rapidly developing and increasingly important topic within materials science.
This book focuses on the study of three sub-groups of structural biological materials:
• Hard tissue engineering, focussing on cortical bone
• Soft tissue engineering
• Fibrous materials, particularly engineering with silk fibers.
The fundamental relationship between structure and properties, and certain aspects of design and engineering, are explored in each of the sub-groups. The importance of these materials, both in their intrinsic properties and specific functions, are illustrated with relevant examples. These depict the successful integration of material properties, architecture and shape, providing a wide range of optimised designs, tailored to specific functions.
Edited by Manuel Elices of the Universidad Politécnica de Madrid, Spain, this book is Volume 4 in the Pergamon Material Series.
For academic researchers and scientists involved in the area of biological materials.
Section and chapter headings and selected sub-headings: Series Preface. Introduction (M. Elices). General Concepts. Structure-Property Relationships in Biological Materials (G. Jeronimidis). Biological materials: scale, heterogeneity, representative volume elements. Fibers: the key building blocks for performance and versatility. Design and Function of Structural Biological Materials (G. Jeronimidis). Design for stiffness and design for strength. Biological fibrous composites and design optimization. Hard Tissue Engineering. Structure and Mechanical Properties of Bone (M. Ontañón et al.). Composition of bone. Integration and organisation levels. Mechanical properties of the cortical of bone. Soft Tissue Engineering. Structure-Properties of Soft Tissues. Articular Cartilage (D. Bader, D. Lee). Structure and composition. Biomechanicas of articular cartilage. Cell seeded repair systems. Bioartificial Implants: Design and Tissue Engineering (R. Brown). Bio-centric logic in bioengineering. Normal structure of adult soft connective tissues. General design of bioartificial tissue and constructs. Examples of bioartificial tissues and constructs. Mechanical Characterisation of Tendons in Vitro (D. Bader, H. Schechtman). Structure and composition. Biomechanics of tendons. Tendon repair strategies. Biomimicking Materials with Smart Polymers (T. Fernández Otero). Conduction polymers. Artificial muscles: electro-chemo-mechanical properties. All organo-aqueous battery: Electric organs. Color mimicking: smart skins. Transducers. Nervous interfaces. Medical dosage. Smart membranes. Three dimensional electrochemical processes and biological mimicking.Engineering with Fibers. Biological Fibrous Materials (C. Viney, E. Rennart). Nature's fibrous materials. Unifying themes. Computer Model for the Mechanical Properties of Synthetic and Biological Polymer Fibers (Y
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- © Pergamon 2000
- 8th May 2000
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@from:David F. Williams @qu:Wherever you look in science policy statements these days, you come across phrases such as 'multidisciplinarity', 'interdisciplinary', technology transfer, and so on. Scientists are being encouraged to work at the interfaces between disciplines or to engage in research and scholarship that encompasses more than their parent discipline. Quite specifically, there is a great deal of current attention being paid to the interface between engineering and the life sciences, and within small but significant sub-sectors, between materials engineering and structural biology and between materials chemistry and cell and molecular biology.
These are exciting areas and much is going on. This book, on Structural Biological Materials, edited by Manuel Elices addresses some of the aspects of the interface between biology and materials science by covering the characteristics of natures own materials and describing how they relate to parameters of materials that are traditionally discussed in the context of synthetic engineering materials. As the Editor points out, nature has tended to optimise the performance of its own materials, so there is much to learn. They have provided the blueprints for some of the concepts of smart materials and provide inspiration to materials scientists that try to emulate their performance in the design of novel, so-called biomimetic materials.
The book is divided into four sections, dealing with basic concepts, soft tissues, hard tissues and engineering with fibres.
Both chapters on concepts have been authored by Dr Jeronimidis, a well-respected scientists in the field of biomimetics. These underline the composite nature of most natural materials and introduce the principles of structure - property relationships, using several examples of natural materials for this purpose. The section on hard tissue is a chapter on bone by Ontanon et al. This covers the major structural features of bone and details of