First published in 1986 under the editorial direction of Dr. Henry J.M. Barnett, Stroke: Pathophysiology, Diagnosis, and Management continues to provide the dependable, current answers you need to effectively combat the increasing incidence of this disease. Dr. J.P. Mohr, together with new associate editors Philip A. Wolf, James C. Grotta, Michael A. Moskowitz, Marc Mayberg, and Rüdiger von Kummer as well as a multitude of expert contributors from around the world, offer you updated and expanded coverage of mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more, equipping you to understand the latest scientific discoveries and make effective use of the newest approaches to diagnosis and treatment. Plus, a new organization and new full-color images make diagnosis easier and more efficient, and full-text online access at www.expertconsult.com allows you to rapidly search this indispensable reference from any computer.
- Gain fresh perspectives and up-to-date insights from the world’s leading authorities on the pathophysiology, diagnosis, and management of stroke.
- Access the comprehensive, expert clinical guidance you need to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan.
Michael A. Moskowitz
Vascular Biology and Atherosclerosis of Cerebral Arteries 03
Alyson A. Miller, Christopher G. Sobey
The Cerebral Microvasculature and Responses to Ischemia 16
Gregory J. del Zoppo, Gerhard F. Hamann
Mechanisms of Thrombosis and Thrombolysis 29
Gregory J. del Zoppo, Mary A. Kalafut
Cerebral Blood Flow and Metabolism in Human Cerebrovascular Disease 44
Allyson R. Zazulia, Joanne Markham, William J. Powers
Histopathology of Cerebral Ischemia 68
ROLAND N. Auer
Molecular and Cellular Mechanisms of Ischemia-Induced Neuronal Death 75
Dimitry Ofengeim, Takahiro Miyawaki, R. Suzanne Zukin
Apoptosis and Related Mechanisms in Cerebral Ischemia 107
Turgay Dalkara, Michael A. Moskowitz
Molecular Pathophysiology of White Matter Anoxic-Ischemic Injury 122
Bruce R. Ransom, Mark P. Goldberg, Selva Baltan
Cerebral Ischemia and Inflammation 138
Costantino Iadecola, Takato Abe, Alexander Kunz, John Hallenbeck
Intracellular Signaling: Mediators and Protective Responses 154
Valina L. Dawson, Ted M. Dawson
Enhancing Brain Reorganization and Recovery of Function after Stroke 162
Michael Chopp, Zheng Gang Zhang
Genetics and Vascular Biology of Brain Vascular Malformations 169
Helen Kim, Ludmila Pawlikowska, William L. Young
Epidemiology and Prevention
Philip A. Wolf
Distribution of Stroke: Heterogeneity by Age, Race, and Sex 189
Virginia J. Howard, George Howard
Epidemiology of Stroke 198
Philip A. Wolf, William B. Kannel
Prognosis after Stroke 219
TATJANA Rundek, Ralph L. Sacco
16 Primary Prevention of Stroke 242
- No. of pages:
- © Saunders 2011
- 31st March 2011
- eBook ISBN:
- Hardcover ISBN:
Daniel Sciarra Professor of Neurology, Department of Neurology, Columbia University, New York, NY, USA.
Professor of Neurology, Chairman, Department of Neurology, University of Texas Medical School at Houston; Director, Stroke Program, Memorial Hermann - Texas Medical Center, Houston, TX
Director, Stroke Program, Memorial Hermann - Texas Medical Center; Professor of Neurology; Chairman, Department of Neurology, University of Texas Medical School at Houston, Houston, TX, USA.
Professor of Neurology, Medicine, and Public Health, Boston University School of Medicine; Principal Investigator, Framingham Heart Study, Boston, MA, USA.
Professor of Neurology, Harvard-MIT Division of Health Science and Technology, Boston, MA, USA.
Executive Director, Seattle Neuroscience Institute at Swedish Medical Center, Seattle, WA, USA.
Professor of Diagnostic Radiology/ Neuroradiology; Head, Department of Neuroradiology, Technische Universitat Dresden; Director, Dresden University Stroke Center, Dresden, Germany