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Stress: Physiology, Biochemistry, and Pathology - 1st Edition - ISBN: 9780128131466, 9780128131473

Stress: Physiology, Biochemistry, and Pathology

1st Edition

Handbook of Stress Series, Volume 3

Editor: George Fink
Hardcover ISBN: 9780128131466
eBook ISBN: 9780128131473
Imprint: Academic Press
Published Date: 18th January 2019
Page Count: 420
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Stress impacts the daily lives of humans and all species on Earth.
Physiology, Biochemistry, and Pathology, the third volume of the Handbook of Stress series, covers stress-related or induced physiology, biochemistry, and pathology. Integrated closely with new behavioral findings and relevance to human conditions, the concepts and data in this volume offer readers cutting-edge information on the physiology of stress.
A sequel to Elsevier’s Encyclopedia of Stress (2000 and 2007), this Handbook of Stress series covers the many significant advances made since then and comprises self-contained volumes that each focus on a specific area within the field of stress. Targeted at scientific and clinical researchers in neuroendocrinology, neuroscience, biomedicine, endocrinology, psychology, psychiatry, the social sciences, and stress and its management in the workplace, this volume and series are ideal for graduate students, post-doctoral fellows, and faculty interested in stress and its consequences.

Key Features

  • Chapters offer impressive scope, with topics addressing stress-related or induced physiology, biochemistry, and pathology
  • Articles carefully selected by eminent stress researchers and prepared by contributors representing outstanding scholarship in the field, with each chapter fully vetted for reliable expert knowledge
  • Richly illustrated with explanatory figures and tables
  • Each chapter has a boxed “Key points” call out section
  • The volume is fully indexed
  • All chapters are electronically available via ScienceDirect
  • Affordably priced, self-contained volume for readers specifically interested in the physiology, biochemistry and pathology of stress, avoiding the need to purchase the whole Handbook series


Neuroscientists, neuroendocrinologists, neurologists, neuropharmacologists, and researchers, graduate students and post-doctoral fellows in neuroscience, psychology and the biomedical sciences

Table of Contents

1. Autonomic Nervous System
2. Corticotropin releasing factor and the urocortins
3. Pro-opiomelanocortin
4. Arousal
5. Brain Regions involved in stress
6. Cerebral Metabolism, Brain Imaging and the stress response
7. Acute Stress Response: Experimental (including startle reflex)
8. Restraint Stress
9. Resilience
10. Stress-Hyporesponsive Period
11. Effects of Extreme High and Low Pressure
12. Avoidance
13. Stress and the Blood-Brain Barrier
14. Multi Drug Resistance P Glycoprotein and other Transporters
15. Glucose Transport, effects of glucocorticoids and adrenaline
16. Hippocampus and hippocampal neurons
17. Memory and Stress
18. Neurogenesis (including neural stem cells)
19. Glia or Neuroglia
20. Excitatory Amino Acids
21. Calcium-Dependent Neurotoxicity
22. GABA (Gamma Aminobutyric Acid) and stress
23. Dopamine, Central
24. Serotonin in Stress
25. Pheromones and stress
26. Instinct Theory
27. Drosophila Studies
28. Proteases in Prokaryotes and Eukaryotic Cell Organelles
29. Febrile Response
30. Thermal Stress
31. Chaperone Proteins and Chaperonopathies
32. Proteosome and autophagy
33. Oxidative Stress
34. Control of Food Intake and Stress
35. Gender differences in stress response


No. of pages:
© Academic Press 2019
18th January 2019
Academic Press
Hardcover ISBN:
eBook ISBN:

About the Editor

George Fink

George Fink

Dr. Fink is Honorary Professor in the University of Melbourne and Professorial Research Fellow at the Florey Institute of Neuroscience and Mental Health. Formerly, he was Scientific Director of the Mental Health Research Institute, Melbourne, Australia. Before returning to Melbourne in 2003, Dr. Fink was University Lecturer in Human Anatomy and Fellow in Physiology and Medicine at Brasenose College and the University of Oxford and served for nearly 20 years as CEO and Director of the UK Medical Research Council’s Brain Metabolism Unit in Edinburgh. He gained distinction through his seminal research discoveries in neuroendocrinology and psychopharmacology published in over 360 scientific papers. Dr. Fink served as President of the European Neuroendocrine Association. His distinctions include Fellow of the Royal Society of Edinburgh, Fellow of the Royal College of Physicians of Edinburgh, Fellow of the Royal Biological Society, Fellow of the Physiological Society, and Honorary Member of the British Society for Neuroendocrinology. Fink was Honorary Professor in the University of Edinburgh, delivered the inaugural Geoffrey Harris Prize Lecture of the British Physiological Society, and the Wolfson Lecture. In 1979 he was awarded the Royal Society - Israel Academy Exchange Fellowship which enabled him to spend a research year at the Weizmann Institute of Science, Rehovot Israel. In 2000 he was awarded the Lifetime Achievement Award of the International Society of Psychoneuroendocrinology. His membership of learned societies includes Emeritus member of the Society for Neuroscience, the Endocrine Society and the Genetics Society of America. Dr. Fink has edited several scientific books with Elsevier, including Stress Science: Neuroendocrinology (2009), Stress Consequences: Mental, Neuropsychological and Socioeconomic (2009), Stress of War, Conflict and Disaster (2010), the Handbook of Neuroendocrinology (2011), and most notably the 4-volume second edition of the Encyclopedia of Stress (2007) on which this new Handbook of Stress series is based. He was founding Editor-in-Chief of the first edition of the Encyclopedia of Stress (2000) which was awarded the 2001 British Medical Association commendation for its contribution to Mental Health. The first volume of his Handbook of Stress series, entitled “Stress: Concepts, Cognition, Emotion, and Behavior”, received the BMA High Commendation in the Health and Social Care category as one of the top titles in its discipline.

Affiliations and Expertise

Professorial Research Fellow and Hon Professor, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia

Ratings and Reviews