Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications - 1st Edition - ISBN: 9780081019955

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications

1st Edition

Volume 2: Advanced nanocarriers for therapeutics

Editors: Abdel Salam Hamdy Makhlouf Nedal Y. Abu-Thabit
Hardcover ISBN: 9780081019955
Imprint: Woodhead Publishing
Published Date: 1st October 2018
Page Count: 700
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Table of Contents

Part I: Dual-responsive polymeric nanocarriers for drug delivery applications
1. Dual-responsive polymeric carriers
2. Magnetic and pH-responsive polymeric nanocarriers
3. Redox and pH-responsive polymeric nanocarriers
4. Thermal and pH responsive polymer-tethered multifunctional magnetic nanoparticles for
5. Ultrasound and pH dually responsive polymers for drug delivery
6. Thermo and pH dual responsive, polymer shell coated, magnetic mesoporous silica nanoparticles for controlled drug release
7. Temperature and pH dual-stimuli responsive polymer microspheres for drug delivery
8. Dual-stimuli responsive polymeric micelles for controlled drug release 
9. Dual-stimuli polymeric nanogels for controlled drug release 
10. Dual responsive PNIPAM–chitosan targeted magnetic nanopolymers for targeted drug delivery
11. Block copolymers for dual responsive controlled drug delivery
12. Biomedical nanoparticle carriers with combined thermal and magnetic response

Part II: Multi-responsive polymeric nanocarriers for drug delivery applications
13. Multi-responsive polymeric carriers
14. Triple stimulus-responsive polypeptide nanoparticles
15. Multi-responsive polymeric nanoparticles for programmed site-specific drug delivery
16. Multi-stimuli-responsive magnetic assemblies 
17. Polymer-coated hollow mesoporous silica nanoparticles for multi-responsive drug delivery
18. Multi-responsive hydrogels for drug delivery Applications

Part III: Therapeutic Applications of stimuli-responsive polymers
19. Future trends, challenges and opportunities with responsive polymer-based drug delivery systems
20. Stimuli-responsive polymersomes for cancer therapy
21. Multi-responsive polymeric carriers for cancer therapy


Nanocarrier systems based on stimuli-responsive polymers are receiving increasing interest because of their ability to undergo conformational changes or to show phase transitions in response to external stimuli.

Innovation and development in the area of stimuli responsive polymer-based nanomaterials for drug delivery is moving fast and there is an increased global demand for biodegradable and biocompatible responsive polymers and nanoparticles for safe drug delivery. This volume discusses in detail the recent trends in designing dual and multi-responsive polymers and nanoparticles for safe drug delivery.

Chapters in Part 1 look at a variety of dual-responsive polymeric nanocarriers for drug delivery and their different stimuli whilst part 2 examines multi-responsive polymeric nanocarriers. The final set of chapters analyses therapeutic applications of stimuli-responsive polymers.

With an emphasis on advanced medical applications and synergistic operational and technological methodologies for improvement of polymers systems for the production of stimuli-responsive polymers, this book is essential reading for materials scientists and researchers working in the drug delivery and pharmaceutical industries.

Key Features

  • Focusses on the most advanced technologies, recent evaluation methods, technical aspects, and advanced synthesis techniques stimuli-responsive polymers
  • Examines advanced medical applications of stimuli responsive polymers
  • Analyses synergistic operational and technological methodologies for improvement of polymers systems for the production of stimuli-responsive polymers for drug delivery


Materials scientists, pharmaceutical scientists and biomedical engineers based at universities, national labs, and medical device companies


No. of pages:
© Woodhead Publishing 2019
Woodhead Publishing
Hardcover ISBN:

Ratings and Reviews

About the Editors

Abdel Salam Hamdy Makhlouf Editor

Dr. Abdel Salam Hamdy Makhlouf is a Professor of Materials Science and Technology in the Central Metallurgical Research and Development Institute, and a Consultant and Expert Reviewer for several international companies, funding agencies and universities, and Advisor Editor for Elsevier, USA. He has won numerous national and international prestigious awards including Humboldt Research Award for Experienced Scientists at Max Planck Institute, Germany, Fulbright Visiting Scholar, NSF Fellow, and Dept. of Energy Fellow, USA, Belgian Federal Science Research Fellowship, Arab Youth Excellence Award in Innovation, Shoman Award in Engineering Science, National Prize of Egypt in Advanced Science and Technology, Egyptian Prize of Excellence in Surface Technology and Corrosion, Egyptian Prize of Excellence and Innovation in Materials Science and their Applications 2009, and An-Najah Prize for Research. Dr. Makhlouf is the editor of 13 books, 20 book chapters and over 180 articles. He is Senior Editor of Insciences Journal, Nanotechnology Section. He supervised and graduated 10 PhD and Master’s students, and 3 postdoctoral fellows. He is also a member of the European Science Foundation College of Expert Reviewers, an Expert Evaluator for the EU’s FP7, expert for the German Ministry of Education and Research, reviewer for the German Academic Exchange Service, and expert for the German Aerospace Center. He is a reviewer and panelist for the NSF programs: MME, MEP, and CREST, and a reviewer for the US Fulbright Commission, the Qatar Foundation, the Kuwait Foundation, and the National Centre of Science and Technology Evaluation, Kazakhstan.

Affiliations and Expertise

Professor of Materials Science and Technology in the Central Metallurgical Research and Development Institute, and International Metallurgical Consultant and Expert Reviewer for several leading companies, funding agencies and universities, organizer and session chair at numerous international conferences, and advisor editor for Elsevier, USA.

Nedal Y. Abu-Thabit Editor

Dr. Nedal Abu-Thabit holds a Ph.D. in chemistry with specialization in polymer chemistry. Currently, Dr. Nedal is an associate professor in the Chemical & Process Engineering Technology department at Jubail Industrial College. Since 2013, he holds the position of the Program Director for Polymer Engineering Technology major. Dr. Nedal has published more than 20 research articles and reviews in refereed journals, 5 book chapters and 2 patents. His research interests in the areas of polymer synthesis, polymer post-functionalization, synthesis of functional polyelectrolytes for fuel cells applications, water sterilization using nanomaterials, synthesis of electrically conducting polymers for sensing applications, preparation of conductive hydrogels and conductive textiles; and isolation of biopolymers from natural sources. In addition, Dr. Nedal has contributed with many articles in the area of educational polymer chemistry.

Affiliations and Expertise

Assistant Professor and Course Director of the Polymer Division in the Department of Chemical and Process Engineering Technololgy, Jubail Industrial College, Saudi Arabia