Sterol Regulation of Ion Channels - 1st Edition - ISBN: 9780128093887

Sterol Regulation of Ion Channels, Volume 80

1st Edition

Serial Volume Editors: Irena Levitan
Hardcover ISBN: 9780128093887
Imprint: Academic Press
Published Date: 1st November 2017
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Table of Contents

Membrane structure and general mechanisms of sterol regulation of ion channels

1. Regulation of ion channels by sterols as boundary lipids

Francisco J. Barrantes

2. Differential effects of sterols on ion channels: specific vs. non-specific interactions

Irena Levitan

Structural determinants of cholesterol-ion channels interactions

3. Regulation of Ca2+-sensitive K+ channels by cholesterol and bile acids via distinct channel subunits and sites

Alex Dopico and Anna Bukiya

4. The role of cholesterol in activation and coupling of nicotinic acetylcholine receptors

John Baenziger

5. Multiple mechanisms of regulation of Transient Receptor Potential ion channels by cholesterol

Tamara Rosenbaum

6. Direct interactions of cholesterol with pentameric ligand-gated ion channels: Testable hypotheses from computational predictions

Grace Brannigan

7. Identification of novel cholesterol binding regions distinct from known cholesterol binding motifs in Kir channels

Avia Rosenhouse-Dantsker

Emerging topics of cholesterol regulation of ion channels

8. Regulation of P2X purinergic receptor signaling by cholesterol

Ruth D. Murrell-Lagnado

9. Modulation of the Drosophila TRPL channel activity by cholesterol

Baruch Minke

10. Sterol regulation of voltage-gated K+ channels

Gyorgy Panyi


Since 1970, Current Topics in Membranes has sought to provide outstanding content to the scientific community on relevant topics that relate to the broad field of membranes. The serial is targeted towards scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. Researchers are encouraged to fully explore their ideas that are often limited in normal scientific publication formats due to strict space constraints. The authors and editors associated with the Current Topics in Membranes series are recognized as world-renowned scientists in their respective fields, making CTM one of the premier serials on membranes

Key Features

  • Contains original material, both textual and illustrative, that make it a very relevant reference
  • Presented in a very comprehensive manner
  • Both researchers in the field and general readers will find this book relevant and up-to-date with regard to its information


Scientists and researchers in biochemistry and molecular and cellular biology


© Academic Press 2017
Academic Press
Hardcover ISBN:

About the Serial Volume Editors

Irena Levitan Serial Volume Editor

Irena Levitan, PhD, is Professor of Medicine and Adjunct Professor of Pharmacology and Bioengineering at the University of Illinois at Chicago. Her current research focuses on cholesterol regulation of ion channels and cellular biomechanics. She published more than 70 papers and book chapters and is a recipient of Guyton Distinguished Lecturer award for quantitative and biophysical work on cholesterol modulation of ion channels and how this can affect integrated organ function from the Association of Chairs of Departments of Physiology.

Affiliations and Expertise

Professor of Medicine and Adjunct Professor of Pharmacology and Bioengineering, University of Illinois, Chicago, USA