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Stem Cells and Cell Signalling in Skeletal Myogenesis - 1st Edition - ISBN: 9780444506634, 9780080569734

Stem Cells and Cell Signalling in Skeletal Myogenesis, Volume 11

1st Edition

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Editor: D.A. Sassoon
eBook ISBN: 9780080569734
Imprint: Elsevier Science
Published Date: 8th February 2002
Page Count: 152
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Table of Contents

General overview of this volume.

  1. The myogenic regulatory factors (C.M. Palmer, M.A. Rudnicki).
  2. Myofiber specification and survival (A. Musarò, N. Rosenthal).
  3. Interactions between the cell cycle and the myogenic program (Jing Huang, M.J. Thayer).
  4. Fiber type specification in vertebrate skeletal muscle (S. Schiaffino, C. Reggiani, G. te Kronnie).
  5. Role of cytokines in skeletal muscle growth and differentiation (B.B. Olwin, et al.).
  6. Somitic and non somitic progenitors of skeletal muscle (G. Cossu). Contributor addresses.


Skeletal muscle development is perhaps one of the best understood processes at the molecular, cellular and organismal level due in large part to the fact that primary myogenic cells (myoblasts) will grow and subsequently differentiate into myotubes in culture. With the advent of reverse mouse genetics, many of the observations gained through the study of myogenic cells in vitro have been directly tested in vivo. What has emerged is a complex but cohesive story of how myogenic cells are initially specified in the vertebrate embryo and how muscle fibers ultimately achieve their respective identities (i.e. fast versus slow) to perform their function. This collection of chapters is focused on these developments. The book discusses old and new directions for the skeletal muscle field and points out directions where the field may eventually progress.


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© Elsevier Science 2002
8th February 2002
Elsevier Science
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About the Editor

D.A. Sassoon

Affiliations and Expertise

Department of Biochemistry and Molecular Biology, Mount Sinai School of Medicine, New York, NY 10029, USA