Six years after the symposium on Stability and Stabilization of Enzymes, a second symposium, Stability and Stabilization of Biocatalysts, on which this book is based, was organized. At the symposium, 210 participants representing all continents came together to learn from 150 oral and poster communications.

The volume brings up-to-date the work already going on, and identifies possible breakthroughs in the research. This timely book therefore presents cutting edge developments in topics such as non-covalent processes in solution, protein engineering and thermophile enzymes, immobilized enzymes, non-conventional media, and whole cells.
An excellent addition to the available literature, it will make a useful contribution to this key area of applied biocatalysis.

Table of Contents

Preface. Acknowledgements. Inactivation Mechanisms and Reactors. Diagnosing the inactivating process of enzymes (O. Misset, A. van Dijk). Stability and stabilization of glucose-fructose oxidoreductase from Zymomonas mobilis against irreversible inactivation during substrate turnover in biochemical reactors (B. Nidetzky et al.). Reactor performance under thermal inactivation and temperature optimization with chitin-immobilized lactase (A. Illanes et al.). Fast in-situ-characterization of biocatalysts long-term stability (M. Boy et al.). Chemical and thermal stability of ferulic acid (feruloyl) esterases from Aspergillus (C.B. Faulds et al.). Stability properties of calf intestinal alkaline phosphatase (U. McKeon et al.). Stabilization of ß-glucanase and its effect on the substrate hydrolysis pattern (I. Markovic et al.). Some factors affecting the behavior of anhydrous &agr;-chymotrypsin at high temperature (D. Pirozzi, G. Greco Jr.). Horseradish peroxidase stability in the course of phenols oxidation (A.M. Egorov et al.). The effect of impurities of crude olive residue oil on the operational stability of the Candida rugosa lipase immobilized in polyurethane foams (A.C. Correia, S. Ferreira-Dias). Approaches for improved identification of mechanisms of enzyme inactivation (M. Polakovic et al.). Stability and stabilization of &agr;-1-4-D-glucan phosphorylases (R. Grießler et al.). Oxidation by hydrogen peroxide of D-amino acid oxidase from Rhodotorula gracilis (V. Obregón et al.). Cosolvent effect on the synthesis of ampicillin and cephalexin with penicillin acylase (C. Aguirre et al.). Conversion and stability studies on enzyme-membrane reactor with lipase immobilized by different methods (T. Venyige et al.). Study of the deactivation process of the glucose oxidase-catalase enzymatic system


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© 1998
Elsevier Science
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About the editor

About the authors

F.J. Plou

Affiliations and Expertise

Department of Biocatalysis, CSIC Institute of Catalysis, Campus University Autonoma, 28049 Madrid, Spain

J.L. Iborra

Affiliations and Expertise

Department of Biochemistry and Molecular Biology "B", Faculty of Chemistry, University of Murcia, Spain

P.J. Halling

Affiliations and Expertise

Department of Pure & Applied Chemistry, University of Strathclyde, Glasgow, UK


@qu:...The book will be a valuable reference texts for all chemist and biochemist working in biotechnology and industrial microbiology. @source:Aslib Book Guide