Spontaneous Pathology of the Laboratory Rabbit

Spontaneous Pathology of the Laboratory Rabbit

1st Edition - April 1, 2023

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  • Editor: Alys Bradley
  • Paperback ISBN: 9780128225288

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Spontaneous Pathology of the Laboratory Rabbit serves as a “go to” text for all pathologists working on laboratory rabbits in safety assessment studies. The book helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathology when assigning cause of death to these animals which are also kept as domestic pets. The book provides a comprehensive text on the spontaneous pathology seen in common laboratory rabbit strains. This is the first book collating information on all organ systems in these strains.

Key Features

  • Consist of multi-author chapters arranged by organ systems
  • Presents color illustrations that depict the most common lesions to augment the descriptions
  • Provides pathologists with common terms that are compliant with the FDA’s Standard for Exchange of Nonclinical Data (SEND) guidelines
  • Gives references for recommended tissue trimming planes


Academies, National and International Associations/Scientific Societies, Veterinary toxicologic pathologists, diagnostic veterinary pathologists, veterinarians, Zoo clinicians and in general practice, Scientists, Technicians, Laboratory managers, Animal caretaker

Table of Contents

  • 1. Introduction to 1st Edition
    2. Choice of Rabbit species
    3. Regulatory issues in the use of Rabbits
    4. Infectious Diseases
    5. Clinical Examination
    6. Digestive System (Oral Cavity, Salivary glands, Esophagus and Stomach, Small and Large Intestine
    7. Liver
    8. Exocrine Pancreas
    9. Urinary System (Kidney, Urinary bladder, ureter, urethra)
    10. Nervous System
    11. Eye and associated glands
    12. Skeletal Muscle
    13. Bone and Joints
    14. Skin and subcutis (including specialized sebaceous glands)
    15. Mammary Gland
    16. Respiratory tract
    17. Haemopoietic and Lymphoid System
    18. Female Reproductive Tract
    19. Male Reproductive Tract
    20. Heart and Blood Vessels
    21. Endocrine System (Thyroid, Parathyroid, Pituitary, Adrenal and Endocrine Pancreas
    22. Clinical Pathology (Hematology and Clinical Chemistry)
    23. Immunohistochemistry

Product details

  • No. of pages: 575
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: April 1, 2023
  • Imprint: Academic Press
  • Paperback ISBN: 9780128225288

About the Editor

Alys Bradley

Dr. Bradley has been with Charles River since 1998 where she is the director of pathology. In this capacity she leads a team of veterinary pathologists and pathology analysts. She has specialist interest and provides consultancy services in neuropathology, non-human primate pathology, medical devices, and cellular therapy products (human and animal stem cells). She is an experienced study pathologist for acute, long term reproductive toxicology, tumorigenicity, oncogenicity, microautoradiography, target animal safety and carcinogenicity studies. She has authored over 700 GLP or GMP compliant toxicological peer reviewed pathology and photomicroscopy reports. She is the GLP and GMP Study Director as well as the Quality Control Manager for GMP pathology services.

Affiliations and Expertise

Director of Pathology, Charles River Laboratories, Inc., Wilmington USA

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