
Spin Resonance Spectroscopy
Principles and applications
Description
Key Features
- Presents a highly interdisciplinary approach by including NMR and EPR applications in chemistry, physics, biology and biotechnology
- Addresses both NMR and EPR, making its concepts and applications implementable in multiple resonance environments and core scientific disciplines
- Features a broad range of methods, examples and illustrations for both NMR and EPR to aid in retention and underscore key concepts
Readership
Chemistry and chemical engineering professionals conducting research using spin resonance spectroscopy in NMR and EPR applications. Secondary audience includes a multi-disciplinary combination of biochemists, medicinal chemists, and physicists conducting comparable research. Upper undergraduate and graduate students taking related coursework forms a tangential audience
Table of Contents
Unit 1: Principle NMR and pulsed NMR
Introduction – Spin Magnetic properties – Resonance condition – Larmor Frequency – NMR instrumentation – comparison of NMR & EPR – chemical shift – spin-spin coupling – Coupling constant – first and second order spectra – simplification of complex spectra – Boltzmann Statistics – Pulsed NMR – Basic principle of FT technique – Relaxation process – Bloch equations – Relaxation times – Line shape and line width analysisUnit 2: 1H and 13C NMR spectroscopy
Interpretation of 1H NMR – assignment of signals – influence of factors on chemical shift of protons – 13C NMR – spin decoupling – double resonance – Nuclear Overhauser Effect – Off Resonance Decoupling – CIDNP – 13C assignment of signals – additivity rule – calculation of chemical shifts for aromatic and aliphatic compounds – 2D NMR –– DEPT 13C – 13C correlation COSY, HETCOR, NOE & NOSEY- multidimensional NMRUnit 3: Applications of NMR
Applications of 31P, 19F and 15N – NMR spectroscopy used in structural problem – NMR of fluxional molecules – evaluation of rate constants – solid state NMR – magic angle spinning – NMR of paramagnetic molecules – contact shifts and shift reagents – NMR imaging – contrast agentsUnit 4: EPR Spectroscopy
Principle of EPR – instrumentation – total spin Hamiltonian – presentation of the spectrum – hyperfine splitting – super hyperfine structure – EPR of hydrogen atom – splitting in isotropic systems involving more than one nucleus – EPR spectra of free radicals in solution – methyl radical, benzene anion, p-benzosemiquinone radical anion, p- nitrobenzoate dianion and naphthalene anion – Evaluation of g and A tensors – factors affecting the magnitude of g values –– anisotropy – zero field splitting – Kramer’s theory & degeneracy – triplet EPRUnit 5: Application and advanced EPR
Application of EPR in transition metal complexes VO2+ Fe3+ Co2+ ,Mn2+, Ni2+ and bis-salicylaldimine copper (II) – Jahn-Teller theory & distortion studies in Cu(II) complexes – evaluation of spin – orbital coupling constant – exchange coupled EPR – multi resonance EPR – cw and pulsed EPR and ENDOR – MEMS and DAVIS – ESEEM – HYSCORE – ESR Spin trapping – spin labeling – EPR imaging
Product details
- No. of pages: 378
- Language: English
- Copyright: © Elsevier 2018
- Published: January 2, 2018
- Imprint: Elsevier
- Paperback ISBN: 9780128136089
- eBook ISBN: 9780128136096