Description

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. Methods in Enzymology is now available online at ScienceDirect — full-text online of volumes 1 onwards. For more information about the Elsevier Book Series on ScienceDirect Program, please visit: http://www.info.sciencedirect.com/bookseries/ This volume is the first of two planned volumes on the topic of small GTPases and their role in disease.

Readership

Researchers in academics and industry studying biochemistry.

Table of Contents

Chapter 1 Rab1b silencing using small interfering RNA for analysis of disease specific function Darren M. Hutt, William E. Balch Chapter 2 Rab8-optineurin-myosin VI: Analysis of interactions and functions in the secretory pathway Margarita V. Chibalina, Rhys C. Roberts, Susan D. Arden, John Kendrick-Jones and Folma Buss Chapter 3 Characterization of Rab27a and JFC1 as constituents of the secretory machinery of prostate specific antigen in prostate carcinoma cells Sergio D. Catz Chapter 4 In vitro assays to characterize inhibitors of the activation of small G proteins by their guanine nucleotide exchange factors Jean-Christophe Zeeh, Bruno Antonny, Jacqueline Cherfils, Mahel Zeghouf Chapter 5 Analysis of small GTPase function in trypanosomes Mark C. Field, David Horn and Mark Carrington Chapter 6 Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis Tom Kirchhausen, Eric Macia, Henry E. Pelish Chapter 7 Identification and verification of Sro7p as an effector of the Sec4p rab GTPase Bianka Grosshans1 and Peter Novick Chapter 8 Characterization of Rab18, a Lipid Droplet Associated Small GTPase Sally Martin, Robert G. Parton Chapter 9 Analysis on the Emerging Role of of Rab3 GTPase-activating Protein in Warburg Micro and Martsolf Syndrome Ayuko Sakane, Jun Miyoshi, Yoshimi Takai, Takuya Sasaki Chapter 10 Identification and Characterization of JRAB/MICAL-L2, a Junctional Rab13-binding Protein Noriyuki Nishimura and Takuya Sasaki

Details

No. of pages:
512
Language:
English
Copyright:
© 2008
Published:
Imprint:
Academic Press
Print ISBN:
9780123739681
Electronic ISBN:
9780080877600