Description

This volume of Progress in Brain Research documents research presented at the 26th International Summer School of Brain Research (Amsterdam, Jun/Jul 2010) and looks at how the oscillations that characterize brain activity vary between task performance - the EEG power and performance modulations, rest - the MRI default mode and other networks, and sleep - the cortical slow oscillations. Studies over the past decade indicate that the study of these slow oscillations is essential for our understanding of plasticity, memory, brain structure from synapse to default mode network, cognition, consciousness and ultimately for our understanding of the mechanisms and functions of sleep and vigilance.

Key Features

  • Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research
  • Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
  • All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
  • Readership

    Neuroscientists, psychologists, neurologists

    Table of Contents

    Preface

    Acknowledgments

    Slow brain oscillations of sleep, resting state, and vigilance

    Introduction

    Slow oscillations of sleep: When, where, who, and why?

    Even slower: The when, where, who, and why of ISOs

    Conclusion

    Electrophysiological correlates of sleep homeostasis in freely behaving rats

    Behavior and brain activity in waking and sleep

    Global and local regulation of sleep

    Homeostatic sleep pressure is reflected in the amplitude and slopes of sleep slow waves

    Homeostatic sleep pressure is reflected in slopes of the early and late components of electrically evoked cortical responses

    Increased homeostatic sleep pressure affects cortical plasticity

    Homeostatic sleep pressure is reflected in synchronization of cortical neurons

    Concluding remarks

    Acknowledgments

    Involvement of cytokines in slow wave sleep

    Introduction

    IL1β and TNFα in sleep regulation

    Upstream and downstream events in the cytokine sleep regulatory cascade

    Brain organization of sleep

    Sleep function

    Acknowledgments

    Genetic determination of sleep EEG profiles in healthy humans

    Introduction

    Sleep–wake regulation

    Heritability of waking EEG

    Trait-like nature of sleep and sleep EEG characteristics

    Heritability of sleep EEG

    Genetic polymorphisms affecting sleep and sleep EEG

    Concluding remarks

    Acknowledgments

    Developmental aspects of sleep slow waves

    Abbreviations

    Introduction

    Characteristics of slow waves

    Development of slow waves—disparities in infants, children and adolescents

    Developmental aspects and their relation to the function of slow waves

    Slow waves and their relation to behavior

    Discussion of the inverted U-shape time course of SWA

    Conclusion and future perspe

    Details

    No. of pages:
    384
    Language:
    English
    Copyright:
    © 2011
    Published:
    Imprint:
    Elsevier
    Print ISBN:
    9780444538390
    Electronic ISBN:
    9780444538383