Sleep Hormones - 1st Edition - ISBN: 9780123946232, 9780123948397

Sleep Hormones, Volume 89

1st Edition

Serial Editors: Gerald Litwack
eBook ISBN: 9780123948397
Hardcover ISBN: 9780123946232
Imprint: Academic Press
Published Date: 7th June 2012
Page Count: 464
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Table of Contents

  1. Neurohormones and Sleep
  2. Eric Frenette, Alben Lui and Michelle Cao

  3. The Role of Orexin/Hypocretin in the Central Nervous System and Peripheral Tissues
  4. Tomomi Tsunematsu and Akihiro Yamanaka

  5. Plasticity in Neurons Synthesizing Wake/Arousal Promoting Hormone Hypocretin/Orexin
  6. Xiao-Bing Gao

  7. Expression of Orexin Receptors in the Pituitary
  8. Tadeusz Kaminski and Nina Smolinska

  9. Transcriptional Regulation of the Hypocretin/Orexin Gene
  10. Susumu Tanaka

  11. Energy Expenditure: Role of Orexin
  12. Jennifer A. Teske and Vijayakumar Mavanji

  13. Orexins: Tissue Localization, Functions and its Relation to Insulin Secretion and Diabetes Mellitus
  14. Ernest Adeghate

  15. Orexin Neurons and Emotional Stress
  16. Tomoyuki Kuwaki and Wei Zhang

  17. Orexin and Central Regulation of Cardiorespiratory System
  18. Israt Z. Shahid, Ahmed A. Rahman and Paul M. Pilowsky

  19. Hypocretin/Orexin Involvement in Reward and Reinforcement
  20. Rodrigo A. España

  21. Glutamate and Orexin Neurons
  22. Ozhan Eyigor and Zehra Minbay

  23. Serotonin Conflict in Sleep-Feeding
  24. Katsunori Nonogaki

  25. Humoral Sleep Regulation; Interleukin-1 and Tumor Necrosis Factor
  26. Kathryn A. Jewett and James M. Krueger

  27. Action of Modafinil through Histaminergic and Orexinergic Neurons
  28. Tomoko Ishizuka, Tomotaka Murotani and Atsushi Yamatodani

  29. Anti-Parkinson Drugs and Orexin Neurons
  30. Hiroshi Katsuki and Shotaro Michinaga

  31. Cocaine and Nicotine Research Illustrates a Range of Hypocretin Mechanisms in Addiction
  32. Corey Baimel, Stephanie L. Borgland and William Corrigall

  33. Sleep and Orexins in Non-Mammalian Vertebrates
  34. Hélène Volkoff

  35. Orexin System in Teleost Fish

Kouhei Matsuda, Morio Azuma and Ki Sung Kang


First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms.

Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

This volume focuses on sleep hormones.

Key Features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field


Researchers, faculty, and graduate students interested in cutting-edge review concerning the molecular and cellular biology of vitamins, hormones, and related factors and co-factors. Libraries and laboratories at institutes with strong programs in cell biology, biochemistry, molecular biology, gene regulation, hormone control, and signal transduction are likely to be interested


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© Academic Press 2012
Academic Press
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About the Serial Editors

Gerald Litwack Serial Editor

Following a liberal arts education with a major in chemistry and biology at Hobart College, Gerald (Gerry) Litwack earned M.S. and PhD degrees in biochemistry from the University of Wisconsin, Madison where he served as a Lecturer in Enzymology before starting a postdoctoral fellowship from the National Foundation for Infantile Paralysis at the Biochemical Institute of the Sorbonne in Paris. His first academic position was assistant professor of biochemistry at Rutgers University where he started his work on hormone action for six years. During this period, he did a sabbatical at the University of California, Berkeley, where he concentrated on rapid enzyme kinetics. In 1960 he accepted an offer of an associate professorship at the University of Pennsylvania Graduate School of Medicine. In 1964, he was invited to be full professor of biochemistry at The Fels Institute for Cancer Research and Molecular Biology at Temple Medical School, simultaneously with a Career Development Award from the NIH, where he later was named Deputy Director of the Institute and the Laura H. Carnell Professor in biochemistry. Subsequently, he was given the Faculty Research Award. He co-discovered ligandin, later found to be in the family of glutathione S-transferases, enzymes that protect the body from carcinogens. In 1991, he moved to the Jefferson Medical College at Thomas Jefferson University as Professor of Biochemistry, Chair of the Department of Pharmacology and Deputy Director of the Kimmel Cancer Research Institute. Later, he became chair of the combined Department of Biochemistry and Molecular Pharmacology and concurrently held the position of Vice Dean for Research. In 2003, he moved to Los Angeles and from 2004-2006 was a Visiting Scholar at the University of California, Los Angeles, in the Department of Biological Chemistry of the Geffen School of Medicine and, in this period, wrote “Human Biochemistry and Disease” a volume of 1254 pages. In 2007, he moved to Scranton, Pennsylvania, as Founding Chair of Basic Sciences and Acting Associate Dean for Research to start a new medical school, The Commonwealth Medical College. Having completing his mission in 2010, he moved to The Institute for Regenerative Medicine, Texas A & M Health Science Center, as Professor of Biochemistry and Associate Director. Currently, he is retired and lives in North Hollywood, California, where he continues as an author and as Series Editor of Vitamins and Hormones. He is involved in writing another textbook and has written a first novel, “One-Eighty”.

Affiliations and Expertise

Toluca Lake, North Hollywood, California, USA