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Single-Cell Omics - 1st Edition - ISBN: 9780128175323, 9780128175330

Single-Cell Omics

1st Edition

Volume 2: Technological Advances and Applications

Editors: Debmalya Barh Vasco Ariston DeCarvalho Azevedo
Paperback ISBN: 9780128175323
eBook ISBN: 9780128175330
Imprint: Academic Press
Published Date: 31st July 2019
Page Count: 384
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Single-cell Omics, Volume 2: Advances in Applications provides the latest single-cell omics applications in the field of biomedicine. The advent of omics technologies have enabled us to identify the differences between cell types and subpopulations at the level of the genome, proteome, transcriptome, epigenome, and in several other fields of omics. The book is divided into two sections: the first is dedicated to biomedical applications, such as cell diagnostics, non-invasive prenatal testing (NIPT), circulating tumor cells, breast cancer, gliomas, nervous systems and autoimmune disorders, and more. The second focuses on cell omics in plants, discussing micro algal and single cell omics, and more.

This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and several members of biomedical field interested in understanding more about single-cell omics and its potential for research and diagnosis.

Key Features

  • Covers the diverse single cell omics applications in the biomedical field
  • Summarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosis
  • Written by experts across the world, it brings different points-of-view and study cases to fully give a comprehensive overview of the topic


Bioinformaticians, molecular diagnostic researchers, clinicians, geneticists

Table of Contents

Section I Single-Cell Omics: Biomedical Applications
1. Single-Cell Diagnostics, Prognosis, and Therapy
2. Single-Cell Omics in Noninvasive Prenatal Testing (NIPT)
3. Single-Cell Omics: Circulating Tumor Cells
4. Single-Cell Technology for Human Gliomas
5. Application of Single-Cell Omics in Breast Cancer
6. Single-Cell Omics: Strategies Towards Theranostic Biomarker Discovery Along the Continuum of Premalignant to Invasive Disease in Oncology
7. Single-Cell Omics in CVDs
8. Single-Cell Omics in Metabolic Disorders
9. Single-Cell Omics in Autoimmune Disorders
10. Single-Cell Omics in Human Reproductive Medicine—Our Clinical Experiences in Single-Cell Therapy
11. Single-Cell Omics for Drug Discovery and Development
12. Single-Cell Omics in Personalized Medicine
13. Cell-Based Medicine and Therapy

Section II Single-Cell Omics in Plants
14. Single-Cell Omics Approaches in Plants
15. Bulk to Individuality: Specifying Plants’ Cellular Functions Through Single-Cell Omics
16. Single-Cell-Type Metabolomics for Crop Improvement
17. Single-Cell Omics in Crop Plants: Opportunities and Challenges


No. of pages:
© Academic Press 2019
31st July 2019
Academic Press
Paperback ISBN:
eBook ISBN:

About the Editors

Debmalya Barh

Debmalya Barh

Debmalya Barh, PhD, holds Master’s and PhD’s degree on Biotechnology and Post-Doc on Bioinformatics. He is honorary Principal Scientist at Centre for Genomics and Applied Gene Technology, Institute of Integrative Omics and Applied Biotechnology, a global platform of multidisciplinary research and advocacy. He has experience with both academic and industrial research and has more than 12 years on bioinformatics and personalized diagnostic/medicine industry experience, with focus on translating academic research into high value commercial products. He has published more than 150 articles in reputed international journals and has edited 15 cutting-edge biotechnology related reference books. He has also co-authored 30+ book chapters. Due to his significant contribution in the field, he has been recognized by Who's Who in the World and Limca Book of Records.

Affiliations and Expertise

Principal Scientist, Centre for Genomics and Applied Gene Technology, Institute of Integrative Omics and Applied Biotechnology, Nonakuri, Purba Medinipur, West Bengal, India

Vasco Ariston DeCarvalho Azevedo

Vasco Azevedo is graduated from veterinary school of the Federal University of Bahia in 1986. He obtained his Master (1989) and Ph.D. (1993) degrees in microbial genetics from Institut National Agronomique Paris-Grignon (INAPG) and Institut National de la Recherche Agronomique (INRA), France, respectively. He did his Post-doctoral research (1994) at Department of Microbiology, School of Medicine, University of Pennsylvania. USA. Since 1995, he is a Professor at Federal University of Minas Gerais (UFMG), Brazil. In 2004, Prof. Azevedo won the Livre-docência contest at the University of São Paulo, which is considered the best university in Brazil. Livre-docência is a degree awarded by the Higher Education Department of Brazil through a public examination open only to the doctoral degree holders and is a recognition to a superior quality of teaching and research. In 2017, Prof. Azevedo defended his third thesis to become a Doctorate in Bioinformatics from the UFMG. He is a also a Fellow of Brazilian Academy of Sciences. He has published 380 research articles, 3 books, and 29 book chapters. Prof. Azevedo is expert in bacterial genetics, genomics, transcriptome, proteomics, and development of new vaccines and diagnostics against infectious diseases. He is pioneer in genetics of Lactic Acid Bacteria and Corynebacterium pseudotuberculosis in Brazil.

Affiliations and Expertise

Professor, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Brazil

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