
Silicon Carbide Biotechnology
A Biocompatible Semiconductor for Advanced Biomedical Devices and Applications
Description
Key Features
- Discusses the properties, processing, characterization, and application of silicon carbide biomedical materials and related technology
- Assesses literature, patents, and FDA approvals for clinical trials, enabling rapid assimilation of data from current disparate sources and promoting the transition from technology R&D, to clinical trials
- Includes more on applications and devices, such as SiC nanowires, biofunctionalized devices, micro-electrode arrays, heart stent/cardiovascular coatings, and continuous glucose sensors, in this new edition
Readership
Biomedical and materials engineers and scientists, device professionals and related specialists searching for a robust biomedical option for implantation with semiconductor effects
Table of Contents
Chapter 1: Silicon Carbide Materials for Biomedical Applications
- Abstract
- 1.1. Preamble
- 1.2. Introduction to the second edition
- 1.3. Summary to the second edition
- 1.4. Introduction to the first edition
- 1.5. Silicon carbide – materials overview
- 1.6. Silicon carbide material growth and processing
- 1.7. Silicon carbide as a biomedical material
- 1.8. Summary to the first edition
- Acknowledgments
Chapter 2: Cytotoxicity of 3C–SiC Investigated Through Strict Adherence to ISO 10993
- Abstract
- 2.1. Introduction
- 2.2. In vitro biomedical testing methods for cytotoxicity
- 2.3. Improved ISO 10993: the BAMBI method
- 2.4. 3C–SiC in vitro evaluation
- 2.5. Summary and the future of 3C–SiC biomedical testing
- Acknowledgments
Chapter 3: Study of the Hemocompatibility of 3C–SiC and a-SiC Films Using ISO 10993-4
- Abstract
- 3.1. Introduction
- 3.2. In vitro biomedical testing methods for cytotoxicity
- 3.3. In vitro assay to assess hemocompatibility of SiC
- 3.4. Summary
- Acknowledgments
Chapter 4: Graphene Functionalization for Biosensor Applications
- Abstract
- 4.1. Introduction
- 4.2. Production of graphene
- 4.3. Graphene characterization methods
- 4.4. Functionalization chemistries
- 4.5. Biofunctionalization
- 4.6. Effect on transport properties
- 4.7. Applications
Chapter 5: SiC Biosensing and Electrochemical Sensing: State of the Art and Perspectives
- Abstract
- 5.1. Introduction
- 5.2. SiC and biomedical applications
- 5.3. Electrochemical biosensors
- 5.4. SiC- and PEDOT:PSS-based biosensors—a complementary competition
- 5.5. SiC-based field effect transistors in biosensing: perspectives and challenges
- 5.6. Conclusions
Chapter 6: SiC RF Antennas for In Vivo Glucose Monitoring and WiFi Applications
- Abstract
- 6.1. Introduction
- 6.2. Blood-glucose monitoring methods
- 6.3. SiC for RF biotechnology
- 6.4. SiC RF antenna development for CGM
- 6.5. Sensor platform development for the ISM band
- 6.6. Summary and future work
Chapter 7: In Vivo Exploration of Robust Implantable Devices Constructed From Biocompatible 3C–SiC
- Abstract
- 7.1. Introduction
- 7.2. Corrosion and chemical resilience
- 7.3. In vivo performance
- 7.4. 3C–SiC for BMI applications—an update
- 7.5. Conclusions
- Acknowledgments
Chapter 8: Amorphous Silicon Carbide for Neural Interface Applications
- Abstract
- 8.1. Introduction
- 8.2. Biotic and abiotic mechanisms of device failure
- 8.3. Role of the material choice in the tissue response
- 8.4. In vitro “neurocompatibility” of a-SiC
- 8.5. In vivo tissue response to a-SiC-coated probes
- 8.6. Summary
- Acknowledgments
Chapter 9: SiC Nanowire-Based Transistors for Electrical DNA Detection
- Abstract
- 9.1. Introduction
- 9.2. Elaboration of SiC nanostructures
- 9.3. Technological process of nanoFETs
- 9.4. Functionalization and DNA hybridization
- 9.5. Electrical detection of DNA
- 9.6. Summary
- Acknowledgments
Chapter 10: Silicon Carbide-Based Nanowires for Biomedical Applications
- Abstract
- 10.1. Introduction
- 10.2. 3C–SiC–SiO2 core–shell nanowires: growth, structure, and luminescence properties
- 10.3. In vitro cytocompatibility of 3C–SiC–SiO2 nanowires
- 10.4. Functionalized 3C–SiC–SiOx nanowires for X-ray-excited photodynamic therapy in vitro
- 10.5. Nanowire platforms: in vitro cytocompatibility and platelet activation
- 10.6. Summary
- Acknowledgments
Product details
- No. of pages: 378
- Language: English
- Copyright: © Elsevier 2016
- Published: March 1, 2016
- Imprint: Elsevier
- Hardcover ISBN: 9780128029930
- eBook ISBN: 9780128030059