Signal Processing for Neuroscientists

Signal Processing for Neuroscientists

An Introduction to the Analysis of Physiological Signals

1st Edition - November 22, 2006

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  • Author: Wim van Drongelen
  • eBook ISBN: 9780080467757

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Description

Signal Processing for Neuroscientists introduces analysis techniques primarily aimed at neuroscientists and biomedical engineering students with a reasonable but modest background in mathematics, physics, and computer programming. The focus of this text is on what can be considered the ‘golden trio’ in the signal processing field: averaging, Fourier analysis, and filtering. Techniques such as convolution, correlation, coherence, and wavelet analysis are considered in the context of time and frequency domain analysis. The whole spectrum of signal analysis is covered, ranging from data acquisition to data processing; and from the mathematical background of the analysis to the practical application of processing algorithms. Overall, the approach to the mathematics is informal with a focus on basic understanding of the methods and their interrelationships rather than detailed proofs or derivations. One of the principle goals is to provide the reader with the background required to understand the principles of commercially available analyses software, and to allow him/her to construct his/her own analysis tools in an environment such as MATLAB®.

Key Features

  • Multiple color illustrations are integrated in the text
  • Includes an introduction to biomedical signals, noise characteristics, and recording techniques
  • Basics and background for more advanced topics can be found in extensive notes and appendices
  • A Companion Website hosts the MATLAB scripts and several data files:  http://www.elsevierdirect.com/companion.jsp?ISBN=9780123708670

Readership

Neuroscientists and biomedical engineering students.

Table of Contents

  • Dedication

    Preface

    Chapter 1: Introduction

    1.1 OVERVIEW

    1.2 BIOMEDICAL SIGNALS

    1.3 BIOPOTENTIALS

    1.4 EXAMPLES OF BIOMEDICAL SIGNALS

    1.5 ANALOG-TO-DIGITAL CONVERSION

    1.6 MOVING SIGNALS INTO THE MATLAB ANALYSIS ENVIRONMENT

    APPENDIX 1.1

    Chapter 2: Data Acquisition

    2.1 RATIONALE

    2.2 THE MEASUREMENT CHAIN

    2.3 SAMPLING AND NYQUIST FREQUENCY IN THE FREQUENCY DOMAIN

    2.4 THE MOVE TO THE DIGITAL DOMAIN

    Appendix 2.1

    Chapter 3: Noise

    3.1 INTRODUCTION

    3.2 NOISE STATISTICS

    3.3 SIGNAL-TO-NOISE RATIO

    3.4 NOISE SOURCES

    APPENDIX 3.1

    APPENDIX 3.2

    APPENDIX 3.3

    APPENDIX 3.4

    Chapter 4: Signal Averaging

    4.1 INTRODUCTION

    4.2 TIME LOCKED SIGNALS

    4.3 SIGNAL AVERAGING AND RANDOM NOISE

    4.4 NOISE ESTIMATES AND THE ± AVERAGE

    4.5 SIGNAL AVERAGING AND NONRANDOM NOISE

    4.6 NOISE AS A FRIEND OF THE SIGNAL AVERAGER

    4.7 EVOKED POTENTIALS

    4.8 OVERVIEW OF COMMONLY APPLIED TIME DOMAIN ANALYSIS TECHNIQUES

    Chapter 5: Real and Complex Fourier Series

    5.1 INTRODUCTION

    5.2 THE FOURIER SERIES

    5.3 THE COMPLEX FOURIER SERIES

    5.4 EXAMPLES

    APPENDIX 5.1

    APPENDIX 5.2

    Chapter 6: Continuous, Discrete, and Fast Fourier Transform

    6.1 INTRODUCTION

    6.2 THE FOURIER TRANSFORM

    6.3 DISCRETE FOURIER TRANSFORM AND THE FFT ALGORITHM

    6.4 UNEVENLY SAMPLED DATA

    Chapter 7: Fourier Transform Applications

    7.1 SPECTRAL ANALYSIS

    7.2 TOMOGRAPHY

    APPENDIX 7.1

    Chapter 8: LTI Systems, Convolution, Correlation, and Coherence

    8.1 INTRODUCTION

    8.2 LINEAR TIME INVARIANT (LTI) SYSTEM

    8.3 CONVOLUTION

    8.4 AUTOCORRELATION AND CROSS-CORRELATION

    8.5 COHERENCE

    APPENDIX 8.1

    Chapter 9: Laplace and z-Transform

    9.1 INTRODUCTION

    9.2 THE USE OF TRANSFORMS TO SOLVE ODEs

    9.3 THE LAPLACE TRANSFORM

    9.4 EXAMPLES OF THE LAPLACE TRANSFORM

    9.5 THE Z-TRANSFORM

    9.6 THE Z-TRANSFORM AND ITS INVERSE

    9.7 EXAMPLE OF THE z-TRANSFORM

    APPENDIX 9.1

    APPENDIX 9.2

    APPENDIX 9.3

    Chapter 10: Introduction to Filters: The RC Circuit

    10.1 INTRODUCTION

    10.2 FILTER TYPES AND THEIR FREQUENCY DOMAIN CHARACTERISTICS

    10.3 RECIPE FOR AN EXPERIMENT WITH AN RC CIRCUIT

    Chapter 11: Filters: Analysis

    11.1 INTRODUCTION

    11.2 THE RC CIRCUIT

    11.3 THE EXPERIMENTAL DATA

    APPENDIX 11.1

    APPENDIX 11.2

    APPENDIX 11.3

    Chapter 12: Filters: Specification, Bode Plot, and Nyquist Plot

    12.1 INTRODUCTION: FILTERS AS LINEAR TIME INVARIANT (LTI) SYSTEMS

    12.2 TIME DOMAIN RESPONSE

    12.3 THE FREQUENCY CHARACTERISTIC

    12.4 NOISE AND THE FILTER FREQUENCY RESPONSE

    Chapter 13: Filters: Digital Filters

    13.1 INTRODUCTION

    13.2 IIR AND FIR DIGITAL FILTERS

    13.3 AR, MA, AND ARMA FILTERS

    13.4 FREQUENCY CHARACTERISTIC OF DIGITAL FILTERS

    13.5 MATLAB IMPLEMENTATION

    13.6 FILTER TYPES

    13.7 FILTER BANK

    13.8 FILTERS IN THE SPATIAL DOMAIN

    APPENDIX 13.1

    Chapter 14: Spike Train Analysis

    14.1 INTRODUCTION

    14.2 POISSON PROCESSES AND POISSON DISTRIBUTIONS

    14.3 ENTROPY AND INFORMATION

    14.4 THE AUTOCORRELATION FUNCTION

    14.5 CROSS-CORRELATION

    APPENDIX 14.1

    APPENDIX 14.2

    Chapter 15: Wavelet Analysis: Time Domain Properties

    15.1 INTRODUCTION

    15.2 WAVELET TRANSFORM

    15.3 OTHER WAVELET FUNCTIONS

    15.4 TWO-DIMENSIONAL APPLICATION

    APPENDIX 15.1

    Chapter 16: Wavelet Analysis: Frequency Domain Properties

    16.1 INTRODUCTION

    16.2 THE CONTINUOUS WAVELET TRANSFORM (CWT)

    16.3 TIME FREQUENCY RESOLUTION

    16.4 MATLAB WAVELET EXAMPLES

    Chapter 17: Nonlinear Techniques

    17.1 INTRODUCTION

    17.2 NONLINEAR DETERMINISTIC PROCESSES

    17.3 LINEAR TECHNIQUES FAIL TO DESCRIBE NONLINEAR DYNAMICS

    17.4 EMBEDDING

    17.5 METRICS FOR CHARACTERIZING NONLINEAR PROCESSES

    17.6 APPLICATION TO BRAIN ELECTRICAL ACTIVITY

    References

    Index

Product details

  • No. of pages: 320
  • Language: English
  • Copyright: © Academic Press 2006
  • Published: November 22, 2006
  • Imprint: Academic Press
  • eBook ISBN: 9780080467757

About the Author

Wim van Drongelen

Wim van Drongelen
Wim van Drongelen studied Biophysics at the University Leiden, The Netherlands. After a period in the Laboratoire d'Electrophysiologie, Université Claude Bernard, Lyon, France, he received the Doctoral degree cum laude. In 1980 he received the Ph.D. degree.

He worked for the Netherlands Organization for the Advancement of Pure Research (ZWO) in the Department of Animal Physiology, Wageningen, The Netherlands. He lectured and founded a Medical Technology Department at the HBO Institute Twente, The Netherlands. In 1986 he joined the Benelux office of Nicolet Biomedical as an Application Specialist and in 1993 he relocated to Madison, WI, USA where he was involved in research and development of equipment for clinical neurophysiology and neuromonitoring.

In 2001 he joined the Epilepsy Center at The University of Chicago, Chicago, IL, USA. Currently he is Professor of Pediatrics, Neurology, and Computational Neuroscience. In addition to his faculty position he serves as Technical and Research Director of the Pediatric Epilepsy Center and he is Senior Fellow with the Computation Institute. Since 2003 he teaches applied mathematics courses for the Committee on Computational Neuroscience. His ongoing research interests include the application of signal processing and modeling techniques to help resolve problems in neurophysiology and neuropathology.

For details of recent work see http://epilepsylab.uchicago.edu/

Affiliations and Expertise

Department of Pediatrics, University of Chicago, Chicago, IL, USA

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