Under the supervision of the series editors, an international team of expert authors have gathered together the latest information on adverse drug effects from the international literature. In addition to describing new reports of adverse drug effects, the authors have subjected those reports to critical analysis, setting them into context in terms of clinical relevance and importance, and cross-referring to previous reports where necessary. New adverse effects are reported and evaluated and previously reported adverse effects are re-evaluated in the light of the most recent information. A special feature is the reviews, in which selected adverse effects are discussed in depth. The use of the book is enhanced by three separate indexes, allowing the reader to enter the text by drug name, adverse effect name, or drug interaction.

Table of Contents

Contributors. List of Special Reviews. How to use this book. Preface (M.N.G. Dukes). Central nervous system stimulants and anorectic agents (R.P. Sequeira). Antidepressant drugs (A.H. Young, P.J. Cowen). Lithium (M. Schou). Drugs of abuse (E. Wong, C. Salzman, A.I. Green). Hypnotics and sedatives (T.C. Jerram). Antipsychotic drugs (D. Capellà, A. Figueras). Anticonvulsant drugs (M.J. Brodie). Opioid analgesics and narcotic antagonists (A.H. Ghodse, R.E. Edwards). Antipyretic analgesics (P. Parise, G. Agnelli). Anti-inflammatory analgesics and drugs used in rheumatoid arthritis and gout (A. Del Favero). General anesthetics and therapeutic gases (Y. Guédès, D. Carlhant-Kowalski). Local anesthetics (A. Chilloleau, Y. Guédès, D. Carlhant-Kowalski). Neuromuscular blocking agents and skeletal muscle relaxants (F.J. Richardson, S. Agoston). Drugs affecting autonomic functions or the extrapyramidal system (E.S. Johnson). Dermatologic drugs, topical agents and cosmetics (A.C. de Groot). Antihistamines (S. Etoe, L. Turner). Antiallergic and antitussive drugs (F.A. Nelemans). Positive inotropic drugs and drugs used in dysrhythmias (J.K. Aronson). &bgr;-adrenoceptor antagonists and antianginal drugs (A.P. Maggioni, M.G. Franzosi, R. Latini). Drugs acting on the cerebral and peripheral circulation (R. Verhaeghe, M. Verstraete). Antihypertensive drugs (F. Zannad). Diuretic drugs (G.T. McInnes). Metals (P.L.C.M. van Riel). Metal antagonists (R.H.B. Meyboom, I.A. Jaffe). Antiseptic drugs and disinfectants (P. Magee). Penicillins, cephalosporins and tetracyclines (T. Midtvedt). Miscellaneous antibiotics (T. Midtvedt). Antifungal drugs (V.K. Lephakhin, A.V. Astakhova). Antiprotozoal drugs (M. Pirmohamed, P.A. Winstanley). Miscellaneous antibacterial drugs (D. Greenwood). Antiviral drugs (P. Reiss, M.D. de Jong). Drugs used in tuberculosis and leprosy (C.J. Ellis). Anthelminthic drugs (A.G.C. Bauer). Enzymes and enzyme inhibitors (M.


© 1994
Elsevier Science
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