Description

The last decade has seen a huge amount of change in the area of sexually transmitted infection control and prevention, including the development of high-profile vaccines for preventing the spread of cervical cancer-causing human papillomavirus (HPV), novel control methods for HIV and AIDS, and even the discussion of more widespread use of controversial abstinence-only sex education programs. Fully revised and updated to reflect the changes of the past ten years, Sexually Transmitted Diseases: Vaccines, Control and Prevention 2nd Edition brings researchers, clinical investigators, clinicians, and students the most up-to-date research, findings and thought on sexual infection prevention, control and therapy available and serves as an essential reference for anyone working in the field.

Key Features

  • Provides comprehensive coverage of epidemiology, physiology and immunology, featuring general preventive strategies such as behavioural modification, barrier methods and topical microbicides
  • Presents individual chapters on Herpes Simplex Virus, Papillomavirus, Hepatitis B, Chlamydia, Gonorrhea, Syphilis, and Bacterial Vaginosis
  • Includes pathogenesis, microbiology and clinical manifestations of each STD, along with current advances in vaccine development

Readership

Researchers in virology, microbiology, infectious disease, and immunology; research clinicians and medical microbiologists, vaccine technolgists, molecular biologists, biochemists, and biotechnologists working on vaccine development; centers for disease control, public and world health organizations, pharmaceutical, and biotechnology companies.

Table of Contents

Contributors

Foreword

Part I: Epidemiology, Physiology, and Immunology

Chapter 1. Global Epidemiology of Sexually Transmitted Diseases

Introduction

Human Immunodeficiency Viruses

Genital Herpes

Cytomegalovirus

Epstein–Barr Virus

Human Herpesvirus 8 (Hhv8)

Hepatitis B

Hepatitis Delta

Hepatitis C

Hepatitis A

Human PapillomaVirus Infection

Chlamydia

Syphilis

Gonorrhea

The Tropical Sexually Transmitted Diseases

Trichomoniasis

References

Chapter 2. The Genital Tract: Anatomical, Developmental, and Microbiological Factors Affecting Sexually Transmitted Disease Acquisition

Introduction

Anatomy of the Female Genital Tract

Blood Supply to and Lymphatic Drainage of the Female Reproductive Tract

Anatomy of the Male Genital Tract: Genitalia

Genital Tract Infections

References

Chapter 3. Mucosal Immunity in the Human Reproductive Tract: Balancing Reproductive Potential with Protection against Sexually Transmitted Pathogens

Introduction

Biology of the Female Reproductive Tract

Innate Immunity in the Female Reproductive Tract

Adaptive Immunity in the Female Reproductive Tract

Mucosal Immunity to Sexually Transmitted Pathogens

Neisseria gonorrhoeae

Chlamydia trachomatis

Candida albicans

Immunology of the Male Reproductive Tract

Summary

Acknowledgements

References

Part II: Strategies for Prevention and Control

Chapter 4. Contextual Factors Associated with Sexually Transmitted Infections

Introduction

Sexually Transmitted Infection Risk

Prevention and Treatment Strategies

Psychosocial Impact

Conclusions

References

Chapter 5. Abstinence and Curricular Approaches to Sexually Transmitted Infect

Details

No. of pages:
526
Language:
English
Copyright:
© 2013
Published:
Imprint:
Academic Press
Print ISBN:
9780123910592
Electronic ISBN:
9780124157569

About the authors

Lawrence Stanberry

Dr. Stanberry is a highly respected authority in vaccine development. Dr. Stanberry focuses on sexually transmitted diseases research and has made important contributions in the area of tropical microbicides an in herpes simplex virus pathogenesis, immunobiology, and antiviral therapy. He has played major roles in the pre-clinical and clinical assessment of many of the herpes vaccines currently in development.

Affiliations and Expertise

College of Physicians and Surgeons, Columbia University, New York, USA

Susan Rosenthal

Affiliations and Expertise

Department of Pediatrics, Columbia University Medical Center - College of Physicians and Surgeons New York-Presbyterian Morgan Stanley Children's Hospital, New York City, New York, USA

Reviews

Praise for the previous edition:

"...presents an abundance of information that provides a clear understanding of sexually transmitted pathogens, factors that must be addressed in efforts to control the spread of disease, and the state of research on barrier methods of prevention and vaccines. ...it will be important reading for students, scientists, and public health practitioners, providing guidance on how best to use the tools we have today while clearly describing the tools needed to complete the armamentarium and the road toward their development."
@source:--David L. Heymann, World Health Organization, in THE NEW ENGLAND JOURNAL OF MEDICINE (April 2001)
@qu:"...the book comprehensively presents the important pathogens of sexually transmitted infections and the research aimed at developing vaccines against them. Past and recent vaccine strategies, current state of vaccine development and their future prospects are discussed in different chapters with great care and sincerity...This book is useful and important reading for those interested in infectious diseases and their prevention, control and vaccine development."
@source:--S. Das in THE JOURNAL OF MEDICAL MICROBIOLOGY (April 2001)
@qu:"very useful and comprehensive information for clinicians, microbiologists and virologists interested in pathogenesis and prevention of STD."
@source:--ACTA VIROLOGICA