Sex Differences in the Human Brain, their Underpinnings and Implications

Sex Differences in the Human Brain, their Underpinnings and Implications

1st Edition - December 3, 2010

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  • Editor: Ivanka Savic-Berglund
  • eBook ISBN: 9780444536310
  • Hardcover ISBN: 9780444536303

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This volume of Progress in Brain Research documents recent developments and research findings in relation to sex and how the brain’s function and behavior differs from men to women. Specific areas include cerebral function, morphology and organization, sexual dimorphism, neural origins,and genetics and epigenetics, as well as potential causes/affects of stress, pain, sexual orientation and identity and other social issues such as distribution of disorders across the sexes and autism.

Key Features

  • Informs and updates on all the latest developments in the field
  • Highlights areas for future research
  • Contributions from leading authorities and industry experts


Neurologists, Neuroscientists, Neuropsychologists

Table of Contents

  • Part I General overview
    1. Anatomical Sex Differences in adult brain (E Luders and A Toga)
    2. Anatomical Sex differences in the adolescent brain (T Paus)
    3. Sex Influences in brain function with focus on Emotional Memory: The Burden of Proof has shifted. (L Cahill)
    4. Cerebral organization and function in relation to sexual orientation and Identity (I Savic, A Garcia-Falgueras and D Swaab)

    Part II The mechanisms behind sex dimorhism in the brain
    5. Genetics of brain sex differences (F Sanchesz and E Villain)
    6. The genetic and epigenetic interplay and of sex differences in the brain (I Qureshi and M Mehler)
    7. Gene expression in neuroendocrine cells during the critical period for sexual differentiation of the brain (K Gagnidze, D Pfaff and J Mong)
    8. Neurosteroids – their impact on the human brain, and potential pharmacologic effects (S Reddy)

    Part III Clinical implications
    9. Sex, gender and pain (J Mogil and A Bailey) 
    10. The skewed sex distribution in affective disorders – a diagnostic, social or biological problem? (M Legato)
    11. Empathizing, Systemizing, and the Extreme Male Brain theory of Autism (S Baron-Cohen)
    12. Gender and the injured brain (P Hurn)

Product details

  • No. of pages: 216
  • Language: English
  • Copyright: © Elsevier 2010
  • Published: December 3, 2010
  • Imprint: Elsevier
  • eBook ISBN: 9780444536310
  • Hardcover ISBN: 9780444536303

About the Serial Volume Editor

Ivanka Savic-Berglund

Dr. Savic’s group is a member of the Stockholm Brain Institute (SBI), a center at the Karolinska Institute for Cognitive and Computational Neuroscience. Her research focuses on the cognitive and emotional decline related to chronic stress as a recognized phenomenon and understanding the underlying mechanisms. They are applying several brain imaging techniques, including PET, to investigate how the human brain is affected by psychosocial stress, and explain the reported emotional and cognitive decline related to stress. The aim is to find biochemical markers of chronic psychosocial stress and develop new treatment strategies.

Affiliations and Expertise

Department of Women's and Children's Health (KBH), Karolinska Universitet and Neurology Clinic, Karolinska Hospital, Stockholm, Sweden

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