Sex and Gender Bias in Technology and Artificial Intelligence

Sex and Gender Bias in Technology and Artificial Intelligence

Biomedicine and Healthcare Applications

1st Edition - May 30, 2022

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  • Editors: Davide Cirillo, Silvina Catuara Solarz, Emre Guney
  • Hardcover ISBN: 9780128213926

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Sex and Gender Bias in Technology and Artificial Intelligence: Biomedicine and Healthcare Applications details the integration of sex and gender as critical factors in innovative technologies (artificial intelligence, digital medicine, natural language processing, robotics) for biomedicine and healthcare applications. By systematically reviewing existing scientific literature, a multidisciplinary group of international experts analyze diverse aspects of the complex relationship between sex and gender, health and technology, providing a perspective overview of the pressing need of an ethically-informed science. The reader is guided through the latest implementations and insights in technological areas of accelerated growth, putting forward the neglected and overlooked aspects of sex and gender in biomedical research and healthcare solutions that leverage artificial intelligence, biosensors, and personalized medicine approaches to predict and prevent disease outcomes. The reader comes away with a critical understanding of this fundamental issue for the sake of better future technologies and more effective clinical approaches.

Key Features

  • First comprehensive title addressing the topic of sex and gender biases and artificial intelligence applications to biomedical research and healthcare
  • Co-published by the Women’s Brain Project, a leading non-profit organization in this area
  • Guides the reader through important topics like the Generation of Clinical Data, Clinical Trials, Big Data Analytics, Digital Biomarkers, Natural Language Processing


Researchers, advanced graduate students, bioengineers, digital therapeutic product developers, and clinicians in the fields of neuroscience, psychiatry, biomedicine, and computer science. Regulators and policy makers

Table of Contents

  •  Introduction

    Silvina Catuara-Solarz, Davide Cirillo, Emre Guney

    1. The Women’s Brain Project

    Maria Teresa Ferretti, Antonella Santuccione Chadha and Simona Mellino


    Section 1. Sex and gender differences and Precision Medicine

    2. Implications of sex-specific differences on clinical studies of human health

    Janet Piñero, Frances-Catherine Quevenco, Laura Furlong and Emre Guney

    3. Socio-economic factors

    Nataly Buslón, Sandra Racionero and Àtia Cortés


    Section 2. Biases in innovative technologies for Biomedicine and Health

    4. Bias and fairness in machine learning and artificial intelligence

    Davide Cirillo and María José Rementeria

    5. Big Data in healthcare from a sex/gender perspective

    Laia Subirats and Gemma Piella

    6. Biases in digital biomarkers and Mobile Health

    Simona Mellino, Czuee Morey and Colin Rohner

    7. Sex and Gender bias in Natural Language Processing

    Davide Cirillo, Hila Gonen, Enrico Santus, Alfonso Valencia, Marta R. Costa-jussà and Marta Villegas

    8. Sex and gender differences in Invasive and non invasive neurotechnologies

    Laura Dubreuil Vall, Tracy Laabs, Harris Eyre, Erin Smith and Silvina Catuara Solarz

    9. Robots and Affective technologies

    Nikolaos Mavridis


    Section 3. Towards Precision Technology

    10. A unified framework for managing sex and gender bias in AI models for Healthcare

    Roberto Confalonieri, Federico Lucchesi, Giovanni Maffei and Silvina Catuara Solarz

    11. Privacy Preserving AI

    Ladina Caduff, Gianluca Diana, Cornelia Kutterer and Spyridon Papasotiriou

    12. Ethics & Society (Societal and Ethical Impact of technologies for Health and Biomedicine)

    Àtia Cortés, Liliana Arroyo and Nataly Buslón


    13. Conclusion

    Emre Guney, Davide Cirillo, Silvina Catuara-Solarz


Product details

  • No. of pages: 278
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: May 30, 2022
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128213926

About the Editors

Davide Cirillo

Davide Cirillo, Ph.D. is a postdoctoral researcher at Barcelona Supercomputing Center (BSC) Computational Biology group, Life Sciences Department. Davide Cirillo received the MSc degree in Pharmaceutical Biotechnology from University of Roma ‘La Sapienza’, Italy, and the PhD degree in Biomedicine from Universitat Pompeu Fabra (UPF) and Center for Genomic Regulation (CRG) of Barcelona, Spain. His research is devoted to the development and application of computational methods in Precision Medicine with a special emphasis on Machine Learning and Artificial Intelligence.

Affiliations and Expertise

Postdoctoral Researcher, Barcelona Supercomputing Center (BSC) Computational Biology Group, Life Sciences Department, Spain

Silvina Catuara Solarz

Silvina Catuara-Solarz, Ph.D. is a translational neuroscientist with expertise in neurodevelopmental, neurodegenerative and psychiatric disorders. After earning a Ph.D. in Biomedicine by the Pompeu Fabra University that she developed at the Centre for Genomic Regulation (CRG), the Hospital del Mar Research Institute (IMIM) (Barcelona, Spain) and the University of California Irvine (Irvine, United States), she worked on target identification for drug development at Janssen Pharmaceutica (Beerse, Belgium). Driven by her interests in merging Technology and Health, she then joined the Health Moonshot at Telefonica Innovation Alpha (Barcelona, Spain) as Strategy Manager where she was involved with the development of evidence-based digital mental health solutions and their efficacy assessment. Given her conviction in the importance of sex and gender for the progress of medicine, Dr. Catuara-Solarz is an active member of the Women’s Brain Project. She has a track record of high impact scientific publications as well as books for the lay audience. Currently Dr. Catuara-Solarz is a selected member of the World Health Organisation Digital Health Roster of Experts and she serves in the European Institute of Innovation and Technology Health (EIT Health) as a project evaluator and a mentor of start-ups in the digital health and medtech sector.

Affiliations and Expertise

Women’s Brain Project (WBP), World Health Organisation (WHO), European Institute of Innovation and Technology Health (EIT Health)

Emre Guney

Emre Guney, Ph.D. is a Senior Research Fellow at the Research Programme on Biomedical Informatics (GRIB), at the Pompeu Fabra University (UPF) and Hospital del Mar Research Institute (IMIM) in Barcelona, Spain and works on developing computational systems biology models for network medicine. He holds a secondary appointment at the Pharmacology & Personalised Medicine department at Maastricht University in the Netherlands. He obtained a B.S. in Computer Engineering from Middle East Technical University (METU), Ph.D. in Biomedicine from Pompeu Fabra University (UPF) and spent several years as a postdoctoral scholar at the Center for Complex Network Research (CCNR) and the Center for Cancer Systems Biology (CCSB), Boston, MA, USA.

Affiliations and Expertise

Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Research; Institute (IMIM) and Pompeu Fabra University (UPF), Barcelona, Spain; Pharmacology and Personalised Medicine department, Maastricht University, Maastricht, The Netherlands

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