Serum Pharmacochemistry of Traditional Chinese Medicine - 1st Edition - ISBN: 9780128111475, 9780128111482

Serum Pharmacochemistry of Traditional Chinese Medicine

1st Edition

Technologies, Strategies and Applications

Editors: Xijun Wang Aihua Zhang Hui Sun
eBook ISBN: 9780128111482
Paperback ISBN: 9780128111475
Imprint: Academic Press
Published Date: 16th January 2017
Page Count: 378
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Description

Serum Pharmacochemistry of Traditional Chinese Medicine: Technologies, Strategies and Applications provides a valuable and indispensable guide on the latest methods, research advances, and applications in this area. Chapters offer cutting-edge information on pharmacokinetics and pharmacodynamics, analytical chemistry, traditional medicine, natural products, bioinformatics, new technologies, therapeutic applications, and more.

For researchers and students in academia and industry, this book provides a hands-on description of experimental techniques, along with beneficial guidelines to help advance research in the fields of Traditional Chinese Medicine and drug development.

Key Features

  • Provides a valuable guide for practitioners of serum pharmacochemistry of Traditional Chinese Medicine, along with insights to its current use and future applications
  • Edited and written by leading scientists at the forefront of this research
  • Presents well written chapters that include an introduction, description of the method, and identification of chemical constituents, with applications and references to the latest research and literature

Readership

Pharmacologists; drug developers; researchers of traditional and herbal medicines; clinicians

Table of Contents

  • List of Contributors
  • Preface
  • Chapter 1. Traditional Chinese Medicine: Current State, Challenges, and Applications
    • 1. Current State
    • 2. Application of TCM
    • 3. The Coming Era of Precision Medicine: What Can We Learn From Chinese Medicine?
    • 4. The Challenges of TCM
    • 5. Future Perspective
  • Chapter 2. Serum Pharmacochemistry of Traditional Chinese Medicine: Historical Development and Strategies
    • 1. Historical Development of Serum Pharmacochemistry of Traditional Chinese Medicine
    • 2. Theoretical Foundation and Research Category of SPT
    • 3. SPT Techniques
    • 4. Application and Future Perspectives of SPT
    • 5. Conclusion
  • Chapter 3. Integrated Serum Pharmacochemistry of TCM and Metabolomics Strategies for Innovative Drug Discovery
    • 1. Introduction
    • 2. Metabolomics in Efficacy Evaluation of Formulae
    • 3. Integrated Serum Pharmacochemistry of TCM With Metabolomics
    • 4. Conclusion
  • Chapter 4. UPLC/MS and Its Potential in Traditional Chinese Medicine Development
    • 1. Introduction
    • 2. Potential Power of UHPLC-MS
    • 3. UHPLC-MS Approach in TCM
    • 4. Identification of Chemical Constituents in TCM Samples
    • 5. Qualitative and Quantitative Analysis of TCM
    • 6. Pharmacokinetics
    • 7. UHPLC-MS-Based Metabolite Identification
    • 8. Metabolomics Application
    • 9. Quality Control of TCM
    • 10. Pharmacological Studies
    • 11. Conclusions and Future Perspective
  • Chapter 5. Analytical Characterization of Yin-Chen-Hao-Tang by Serum Pharmacochemistry of TCM
    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussions
    • 4. Conclusion
  • Chapter 6. Pharmacokinetic Strategy for Screening the Effective Components From YCHT
    • 1. Introduction
    • 2. Experimental
    • 3. Results
    • 4. Discussion
    • 5. Conclusion
  • Chapter 7. Synergism Effects of Active Ingredients From YCHT
    • 1. Introduction
    • 2. Materials and Methods
    • 3. Results
    • 4. Discussion
    • 5. Conclusion
  • Chapter 8. Serum Pharmacochemistry of TCM for Screening the Active Ingredients From Wen-Xin Formulae
    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussion
    • 4. Conclusion
  • Chapter 9. Characterization and Pharmacokinetic Study of Multiple Constituents From Shengmai San
    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussion
    • 4. Conclusion
  • Chapter 10. Multivariate Data Processing Tools to Screen the Active Ingredients From Kai-Xin-San
    • 1. Introduction
    • 2. Material and Methods
    • 3. Results and Discussion
    • 4. Conclusion
  • Chapter 11. Serum Pharmacochemistry of TCM for Determining the Active Ingredients of Shuanghuanglian Formulae
    • 1. Introduction
    • 2. Material and Methods
    • 3. Results
    • 4. Discussion
    • 5. Conclusion
  • Chapter 12. Pharmacokinetic–Pharmacodynamic Study of Zhi Zhu Wan
    • 1. Introduction
    • 2. Experimental
    • 3. Results
    • 4. Discussion
    • 5. Conclusion
  • Chapter 13. Identification of the Absorbed Components of Shaoyao-Gancao Decoction
    • 1. Introduction
    • 2. Materials and Methods
    • 3. Results and Discussion
    • 4. Conclusions
  • Chapter 14. Rapid Analysis of Multiple Constituents of Suanzaoren Decoction by UPLC-MS
    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussion
    • 4. Conclusion
  • Chapter 15. UPLC-MS Analysis of the Chemical Constituents of Liuwei Dihuang Wan
    • 1. Introduction
    • 2. Material and Methods
    • 3. Results and Discussion
    • 4. Conclusion
  • Chapter 16. Multivariate Data Analysis for Rapid Identification of Chemical Constituents of Simiao Wan
    • 1. Introduction
    • 2. Material and Methods
    • 3. Results and Discussion
    • 4. Conclusion
  • Chapter 17. Time-Course Study of Multicomponents After Oral Administration of Stemonae Radix
    • 1. Introduction
    • 2. Experimental
    • 3. Results
    • 4. Discussion
    • 5. Conclusion
  • Chapter 18. Global Characterization of Chemical Constituents of Phellodendri amurensis Cortex
    • 1. Introduction
    • 2. Material and Methods
    • 3. Results and Discussion
    • 4. Conclusion
  • Chapter 19. Comparative Analysis of Chemical Constituents of Phellodendri amurensis Cortex and Zhibai Dihuang Pill
    • 1. Introduction
    • 2. Materials and Methods
    • 3. Results and Discussion
    • 4. Conclusion
  • Chapter 20. UPLC-MS Determining the Active Ingredients of Herbal Fructus Corni In Vivo
    • 1. Introduction
    • 2. Material and Methods
    • 3. Results and Discussion
    • 4. Conclusion
  • Chapter 21. Serum Pharmacochemistry of TCM Screening the Bioactive Components From Moutan Cortex
    • 1. Introduction
    • 2. Material and Methods
    • 3. Results
    • 4. Discussion
    • 5. Conclusion
  • Chapter 22. Rapid Analysis of Constituents and Metabolites From Extracts of Acanthopanax senticosus Harms Leaf
    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussion
    • 4. Conclusion
  • Chapter 23. Systematic Characterization of the Absorbed Components of Acanthopanax senticosus Stem
    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussion
    • 4. Conclusion
  • Chapter 24. Identification of the Absorbed Constituents of Schisandra Lignans by Serum Pharmacochemistry of TCM
    • 1. Introduction
    • 2. Experimental
    • 3. Results
    • 4. Discussion
    • 5. Conclusion
  • Index

Details

No. of pages:
378
Language:
English
Copyright:
© Academic Press 2017
Published:
Imprint:
Academic Press
eBook ISBN:
9780128111482
Paperback ISBN:
9780128111475

About the Editor

Xijun Wang

Xijun Wang, PhD, is a Professor of Pharmacology of Traditional Chinese Medicine (TCM) and Vice President at Heilongjiang University of Chinese Medicine in China. Dr. Wang has published more than 150 papers in peer-reviewed journals, received the National Science and Technology Progress Award and National Technological Invention Award and holds 20 patents. His research focuses on serum Pharmacochemistry of Traditional Chinese Medicines. By integrating metabolomics with serum Pharmacochemistry of TCM Dr. Wang has developed and established the theory and research methods of Chinmedomics, whereby the clinical efficacy of TCM formulae can be measured and analyzed.

Affiliations and Expertise

Professor and General Director, National Traditional Chinese Medicine (TCM) Key Laboratory of Serum Pharmacochemistry, Laboratory of Metabolomics and Chinmedomics Vice President, Heilongjiang University of Chinese Medicine, Harbin, China

Aihua Zhang

Affiliations and Expertise

National Traditional Chinese Medicine (TCM) Key Laboratory of Serum Pharmacochemistry, Laboratory of Metabolomics and Chinmedomics, Harbin, China

Hui Sun

Affiliations and Expertise

National Traditional Chinese Medicine (TCM) Key Laboratory of Serum Pharmacochemistry, Laboratory of Metabolomics and Chinmedomics, Harbin, China