Serum Pharmacochemistry of Traditional Chinese Medicine

Serum Pharmacochemistry of Traditional Chinese Medicine

Technologies, Strategies and Applications

1st Edition - December 27, 2016

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  • Editors: Xijun Wang, Aihua Zhang, Hui Sun
  • Paperback ISBN: 9780128111475
  • eBook ISBN: 9780128111482

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Description

Serum Pharmacochemistry of Traditional Chinese Medicine: Technologies, Strategies and Applications provides a valuable and indispensable guide on the latest methods, research advances, and applications in this area. Chapters offer cutting-edge information on pharmacokinetics and pharmacodynamics, analytical chemistry, traditional medicine, natural products, bioinformatics, new technologies, therapeutic applications, and more. For researchers and students in academia and industry, this book provides a hands-on description of experimental techniques, along with beneficial guidelines to help advance research in the fields of Traditional Chinese Medicine and drug development.

Key Features

  • Provides a valuable guide for practitioners of serum pharmacochemistry of Traditional Chinese Medicine, along with insights to its current use and future applications
  • Edited and written by leading scientists at the forefront of this research
  • Presents well written chapters that include an introduction, description of the method, and identification of chemical constituents, with applications and references to the latest research and literature

Readership

Pharmacologists; drug developers; researchers of traditional and herbal medicines; clinicians

Table of Contents

  • Chapter 1. Traditional Chinese Medicine: Current State, Challenges, and Applications

    • 1. Current State
    • 2. Application of TCM
    • 3. The Coming Era of Precision Medicine: What Can We Learn From Chinese Medicine?
    • 4. The Challenges of TCM
    • 5. Future Perspective

    Chapter 2. Serum Pharmacochemistry of Traditional Chinese Medicine: Historical Development and Strategies

    • 1. Historical Development of Serum Pharmacochemistry of Traditional Chinese Medicine
    • 2. Theoretical Foundation and Research Category of SPT
    • 3. SPT Techniques
    • 4. Application and Future Perspectives of SPT
    • 5. Conclusion

    Chapter 3. Integrated Serum Pharmacochemistry of TCM and Metabolomics Strategies for Innovative Drug Discovery

    • 1. Introduction
    • 2. Metabolomics in Efficacy Evaluation of Formulae
    • 3. Integrated Serum Pharmacochemistry of TCM With Metabolomics
    • 4. Conclusion

    Chapter 4. UPLC/MS and Its Potential in Traditional Chinese Medicine Development

    • 1. Introduction
    • 2. Potential Power of UHPLC-MS
    • 3. UHPLC-MS Approach in TCM
    • 4. Identification of Chemical Constituents in TCM Samples
    • 5. Qualitative and Quantitative Analysis of TCM
    • 6. Pharmacokinetics
    • 7. UHPLC-MS-Based Metabolite Identification
    • 8. Metabolomics Application
    • 9. Quality Control of TCM
    • 10. Pharmacological Studies
    • 11. Conclusions and Future Perspective

    Chapter 5. Analytical Characterization of Yin-Chen-Hao-Tang by Serum Pharmacochemistry of TCM

    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussions
    • 4. Conclusion

    Chapter 6. Pharmacokinetic Strategy for Screening the Effective Components From YCHT

    • 1. Introduction
    • 2. Experimental
    • 3. Results
    • 4. Discussion
    • 5. Conclusion

    Chapter 7. Synergism Effects of Active Ingredients From YCHT

    • 1. Introduction
    • 2. Materials and Methods
    • 3. Results
    • 4. Discussion
    • 5. Conclusion

    Chapter 8. Serum Pharmacochemistry of TCM for Screening the Active Ingredients From Wen-Xin Formulae

    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussion
    • 4. Conclusion

    Chapter 9. Characterization and Pharmacokinetic Study of Multiple Constituents From Shengmai San

    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussion
    • 4. Conclusion

    Chapter 10. Multivariate Data Processing Tools to Screen the Active Ingredients From Kai-Xin-San

    • 1. Introduction
    • 2. Material and Methods
    • 3. Results and Discussion
    • 4. Conclusion

    Chapter 11. Serum Pharmacochemistry of TCM for Determining the Active Ingredients of Shuanghuanglian Formulae

    • 1. Introduction
    • 2. Material and Methods
    • 3. Results
    • 4. Discussion
    • 5. Conclusion

    Chapter 12. Pharmacokinetic–Pharmacodynamic Study of Zhi Zhu Wan

    • 1. Introduction
    • 2. Experimental
    • 3. Results
    • 4. Discussion
    • 5. Conclusion

    Chapter 13. Identification of the Absorbed Components of Shaoyao-Gancao Decoction

    • 1. Introduction
    • 2. Materials and Methods
    • 3. Results and Discussion
    • 4. Conclusions

    Chapter 14. Rapid Analysis of Multiple Constituents of Suanzaoren Decoction by UPLC-MS

    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussion
    • 4. Conclusion

    Chapter 15. UPLC-MS Analysis of the Chemical Constituents of Liuwei Dihuang Wan

    • 1. Introduction
    • 2. Material and Methods
    • 3. Results and Discussion
    • 4. Conclusion

    Chapter 16. Multivariate Data Analysis for Rapid Identification of Chemical Constituents of Simiao Wan

    • 1. Introduction
    • 2. Material and Methods
    • 3. Results and Discussion
    • 4. Conclusion

    Chapter 17. Time-Course Study of Multicomponents After Oral Administration of Stemonae Radix

    • 1. Introduction
    • 2. Experimental
    • 3. Results
    • 4. Discussion
    • 5. Conclusion

    Chapter 18. Global Characterization of Chemical Constituents of Phellodendri amurensis Cortex

    • 1. Introduction
    • 2. Material and Methods
    • 3. Results and Discussion
    • 4. Conclusion

    Chapter 19. Comparative Analysis of Chemical Constituents of Phellodendri amurensis Cortex and Zhibai Dihuang Pill

    • 1. Introduction
    • 2. Materials and Methods
    • 3. Results and Discussion
    • 4. Conclusion

    Chapter 20. UPLC-MS Determining the Active Ingredients of Herbal Fructus Corni In Vivo

    • 1. Introduction
    • 2. Material and Methods
    • 3. Results and Discussion
    • 4. Conclusion

    Chapter 21. Serum Pharmacochemistry of TCM Screening the Bioactive Components From Moutan Cortex

    • 1. Introduction
    • 2. Material and Methods
    • 3. Results
    • 4. Discussion
    • 5. Conclusion

    Chapter 22. Rapid Analysis of Constituents and Metabolites From Extracts of Acanthopanax senticosus Harms Leaf

    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussion
    • 4. Conclusion

    Chapter 23. Systematic Characterization of the Absorbed Components of Acanthopanax senticosus Stem

    • 1. Introduction
    • 2. Experimental
    • 3. Results and Discussion
    • 4. Conclusion

    Chapter 24. Identification of the Absorbed Constituents of Schisandra Lignans by Serum Pharmacochemistry of TCM

    • 1. Introduction
    • 2. Experimental
    • 3. Results
    • 4. Discussion
    • 5. Conclusion

Product details

  • No. of pages: 378
  • Language: English
  • Copyright: © Academic Press 2017
  • Published: December 27, 2016
  • Imprint: Academic Press
  • Paperback ISBN: 9780128111475
  • eBook ISBN: 9780128111482

About the Editors

Xijun Wang

Xijun Wang, PhD, is a Professor of Pharmacology of Traditional Chinese Medicine (TCM) and Vice President at Heilongjiang University of Chinese Medicine in China. Dr. Wang has published more than 150 papers in peer-reviewed journals, received the National Science and Technology Progress Award and National Technological Invention Award and holds 20 patents. His research focuses on serum Pharmacochemistry of Traditional Chinese Medicines. By integrating metabolomics with serum Pharmacochemistry of TCM Dr. Wang has developed and established the theory and research methods of Chinmedomics, whereby the clinical efficacy of TCM formulae can be measured and analyzed.

Affiliations and Expertise

Professor and General Director, National Traditional Chinese Medicine (TCM) Key Laboratory of Serum Pharmacochemistry, Laboratory of Metabolomics and Chinmedomics Vice President, Heilongjiang University of Chinese Medicine, Harbin, China

Aihua Zhang

Affiliations and Expertise

National Traditional Chinese Medicine (TCM) Key Laboratory of Serum Pharmacochemistry, Laboratory of Metabolomics and Chinmedomics, Harbin, China

Hui Sun

Affiliations and Expertise

National Traditional Chinese Medicine (TCM) Key Laboratory of Serum Pharmacochemistry, Laboratory of Metabolomics and Chinmedomics, Harbin, China

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