Serum Pharmacochemistry of Traditional Chinese Medicine

Serum Pharmacochemistry of Traditional Chinese Medicine: Technologies, Strategies and Applications provides a valuable and indispensable guide on the latest methods, research advances, and applications in this area. Chapters offer cutting-edge information on pharmacokinetics and pharmacodynamics, analytical chemistry, traditional medicine, natural products, bioinformatics, new technologies, therapeutic applications, and more.

For researchers and students in academia and industry, this book provides a hands-on description of experimental techniques, along with beneficial guidelines to help advance research in the fields of Traditional Chinese Medicine and drug development.

• Provides a valuable guide for practitioners of serum pharmacochemistry of Traditional Chinese Medicine, along with insights to its current use and future applications
• Edited and written by leading scientists at the forefront of this research
• Presents well written chapters that include an introduction, description of the method, and identification of chemical constituents, with applications and references to the latest research and literature

Pharmacologists; drug developers; researchers of traditional and herbal medicines; clinicians

• List of Contributors
• Preface
• Chapter 1. Traditional Chinese Medicine: Current State, Challenges, and Applications
  • 1. Current State
  • 2. Application of TCM
  • 3. The Coming Era of Precision Medicine: What Can We Learn From Chinese Medicine?
  • 4. The Challenges of TCM
  • 5. Future Perspective
• Chapter 2. Serum Pharmacochemistry of Traditional Chinese Medicine: Historical Development and Strategies
  • 1. Historical Development of Serum Pharmacochemistry of Traditional Chinese Medicine
  • 2. Theoretical Foundation and Research Category of SPT
  • 3. SPT Techniques
  • 4. Application and Future Perspectives of SPT
  • 5. Conclusion
• Chapter 3. Integrated Serum Pharmacochemistry of TCM and Metabolomics Strategies for Innovative Drug Discovery
  • 1. Introduction
  • 2. Metabolomics in Efficacy Evaluation of Formulae
  • 3. Integrated Serum Pharmacochemistry of TCM With Metabolomics
  • 4. Conclusion
• Chapter 4. UPLC/MS and Its Potential in Traditional Chinese Medicine Development
  • 1. Introduction
  • 2. Potential Power of UHPLC-MS
  • 3. UHPLC-MS Approach in TCM
  • 4. Identification of Chemical Constituents in TCM Samples
  • 5. Qualitative and Quantitative Analysis of TCM
  • 6. Pharmacokinetics
  • 7. UHPLC-MS-Based Metabolite Identification
  • 8. Metabolomics Application
  • 9. Quality Control of TCM
  • 10. Pharmacological Studies
  • 11. Conclusions and Future Perspective
• Chapter 5. Analytical Characterization of Yin-Chen-Hao-Tang by Serum Pharmacochemistry of TCM
  • 1. Introduction
  • 2. Experimental
  • 3. Results and Discussions
  • 4. Conclusion
• Chapter 6. Pharmacokinetic Strategy for Screening the Effective Components From YCHT
  • 1. Introduction
  • 2. Experimental
  • 3. Results
  • 4. Discussion
  • 5. Conclusion
• Chapter 7. Synergism Effects of Active Ingredients From YCHT
  • 1. Introduction
  • 2. Materials and Methods
  • 3. Results
  • 4. Discussion
  • 5. Conclusion
• Chapter 8. Serum Pharmacochemistry of TCM for Screening the Active Ingredients From Wen-Xin Formulae
  • 1. Introduction
  • 2. Experimental
  • 3. Results and Discussion
  • 4. Conclusion
• Chapter 9. Characterization and Pharmacokinetic Study of Multiple Constituents From Shengmai San
  • 1. Introduction
  • 2. Experimental
  • 3. Results and Discussion
  • 4. Conclusion
• Chapter 10. Multivariate Data Processing Tools to Screen the Active Ingredients From Kai-Xin-San
  • 1. Introduction
  • 2. Material and Methods
  • 3. Results and Discussion
  • 4. Conclusion
• Chapter 11. Serum Pharmacochemistry of TCM for Determining the Active Ingredients of Shuanghuanglian Formulae
  • 1. Introduction
  • 2. Material and Methods
  • 3. Results
  • 4. Discussion
  • 5. Conclusion
• Chapter 12. Pharmacokinetic–Pharmacodynamic Study of Zhi Zhu Wan
  • 1. Introduction
  • 2. Experimental
  • 3. Results
  • 4. Discussion
  • 5. Conclusion
• Chapter 13. Identification of the Absorbed Components of Shaoyao-Gancao Decoction
  • 1. Introduction
  • 2. Materials and Methods
  • 3. Results and Discussion
  • 4. Conclusions
• Chapter 14. Rapid Analysis of Multiple Constituents of Suanzaoren Decoction by UPLC-MS
  • 1. Introduction
  • 2. Experimental
  • 3. Results and Discussion
  • 4. Conclusion
• Chapter 15. UPLC-MS Analysis of the Chemical Constituents of Liuwei Dihuang Wan
  • 1. Introduction
  • 2. Material and Methods
  • 3. Results and Discussion
  • 4. Conclusion
• Chapter 16. Multivariate Data Analysis for Rapid Identification of Chemical Constituents of Simiao Wan
  • 1. Introduction
  • 2. Material and Methods
  • 3. Results and Discussion
  • 4. Conclusion
• Chapter 17. Time-Course Study of Multicomponents After Oral Administration of Stemonae Radix
  • 1. Introduction
  • 2. Experimental
  • 3. Results
  • 4. Discussion
  • 5. Conclusion
• Chapter 18. Global Characterization of Chemical Constituents of Phellodendri amurensis Cortex
  • 1. Introduction
  • 2. Material and Methods
  • 3. Results and Discussion
  • 4. Conclusion
• Chapter 19. Comparative Analysis of Chemical Constituents of Phellodendri amurensis Cortex and Zhibai Dihuang Pill
  • 1. Introduction
  • 2. Materials and Methods
  • 3. Results and Discussion
  • 4. Conclusion
• Chapter 20. UPLC-MS Determining the Active Ingredients of Herbal Fructus Corni In Vivo
  • 1. Introduction
  • 2. Material and Methods
  • 3. Results and Discussion
  • 4. Conclusion
• Chapter 21. Serum Pharmacochemistry of TCM Screening the Bioactive Components From Moutan Cortex
  • 1. Introduction
  • 2. Material and Methods
  • 3. Results
  • 4. Discussion
  • 5. Conclusion
• Chapter 22. Rapid Analysis of Constituents and Metabolites From Extracts of Acanthopanax senticosus Harms Leaf
  • 1. Introduction
  • 2. Experimental
  • 3. Results and Discussion
  • 4. Conclusion
• Chapter 23. Systematic Characterization of the Absorbed Components of Acanthopanax senticosus Stem
  • 1. Introduction
  • 2. Experimental
  • 3. Results and Discussion
  • 4. Conclusion
• Chapter 24. Identification of the Absorbed Constituents of Schisandra Lignans by Serum Pharmacochemistry of TCM
  • 1. Introduction
  • 2. Experimental
  • 3. Results
  • 4. Discussion
  • 5. Conclusion
• Index