SERS for Point-of-care and Clinical Applications

SERS for Point-of-care and Clinical Applications

1st Edition - July 1, 2022

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  • Editor: Andrew Fales
  • Paperback ISBN: 9780128205488

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SERS for Point-of-care and Clinical Applications focuses on the use of Surface-Enhanced Raman Spectroscopy (also known as Surface-Enhanced Raman Scattering) techniques in clinical and point-of-care settings. Sections provide an overview of SERS biomedical applications, providing in-depth information about point-of-care and clinical applications of SERS using specific examples from current literature. These applications are not always immediately evident to newcomers in the field, as Raman and SERS are often introduced as analytical methods for chemical analysis. This book offers a concise introduction to the biomedical applications of SERS for graduate students, scientists and researchers in all related fields.

Key Features

  • Highlights point-of-care applications for SERS
  • Covers the recent biomedical applications of SERS carried out by leaders in the field
  • Includes chapters on SERS probes and labels and label-free uses of SERS


Scientists, researchers, and graduate students using Surface-Enhanced Raman Spectroscopy (SERS) in the fields of chemistry, biology, biophotonics, nanotechnology, and physics who are interested applying SERS in clinical and point-of-care settings

Table of Contents

  • Part 1: Background
    1. Label-free SERS in biomedical applications
    2. SERS probes and labels for biomedical applications

    Part 2: Point-of-Care applications
    3. SERS biosensors for infectious disease diagnosis
    4. SERS-based molecular sentinels for nucleic acid detection
    5. Quantitative determination of cellular biomarker expression for identification of effective cancer treatments using SERS biosensors
    6. Nanoporous gold substrates for SERS-based in vitro diagnostics

    Part 3: (pre-)Clinical applications
    7. SERS detection of oral and GI cancerous tissues
    8. Surface-enhanced spatially offset Raman spectroscopy for breast cancer detection 9. Brain tumor delineation using gold nanostar SERS tags
    10. Multiplexed cancer immunoimaging using SERS

Product details

  • No. of pages: 316
  • Language: English
  • Copyright: © Elsevier 2022
  • Published: July 1, 2022
  • Imprint: Elsevier
  • Paperback ISBN: 9780128205488

About the Editor

Andrew Fales

Andrew Fales is a Staff Fellow in Biomedical Engineer and works in the Division of Biomedical Physics, Office of Science and Engineering Laboratories at the Center for Devices and Radiological Health, U.S. Food and Drug Administration.

Affiliations and Expertise

Staff Fellow, Biomedical Engineer, Division of Biomedical Physics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration

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