Semiconducting Silicon Nanowires for Biomedical Applications

Part I: Introduction to silicon nanowires for biomedical applications: Synthesis and fundamental properties
1. Overview of semiconducting silicon nanowires for biomedical applications
2. Growth and characterization of semiconducting silicon nanowires for biomedical applications
3. Surface modification of semiconducting silicon nanowires for biosensing applications
4. Biocompatibility of semiconducting silicon nanowires

Part II: Silicon nanowires for delivery and tissue engineering applications
5. Functional semiconducting silicon nanowires for cellular binding and internalization
6. Functional semiconducting silicon nanowires and their composites as tissue scaffolds
7. Mediated differentiation of stem cells by engineered semiconducting silicon nanowires
8. Nanoneedles devices for biomedicine
9. Therapeutic platforms based on silicon nanotubes
10. Silicon nanowires as spatially-defined therapeutics

Part III: Silicon nanowires for detection and sensing
11. Semiconducting silicon nanowire array fabrication for high throughput screening in the biosciences
12. Nanostructured silicon for biological modulation
13. CMOS-compatible silicon nanowire field-effect transistors: Where nanotechnology pushes the limits in biosensing
14. Silicon nanowire composites for biosensing and therapy

Part IV: Future opportunities and challenges
15. The competition: non-silicon nanowire/nanotube strategies in nanomedicine
16. Commercialization of silicon nanowire-based biotechnologies

Semiconducting Silicon Nanowires for Biomedical Applications reviews the fabrication, properties and biomedical applications of this key material. Sections review basics, growth, characterization, biocompatibility, and surface modification of semiconducting. Chapters go on to focus on silicon nanowires for tissue engineering and delivery applications, including cellular binding and internalization, orthopedic tissue scaffolds, mediated differentiation of stem cells, and silicon nanoneedles for drug delivery. Finally, the book highlights the use of silicon nanowires for detection and sensing. These chapters explore the fabrication and use of semiconducting silicon nanowire arrays for high-throughput screening in the biosciences, neural cell pinning on surfaces, and probe-free platforms for biosensing.

This book provides a comprehensive resource for biomaterials scientists who are focused on biosensors, drug delivery and tissue engineering, but it is also ideal for researchers and developers in industry and academia who are concerned with nanoscale biomaterials, in particular electronically-responsive biomaterials.

• Reviews the growth, characterization, biocompatibility, and surface modification of semiconducting silicon nanowires
• Describes silicon nanowires for tissue engineering and delivery applications, including cellular binding and internalization, orthopedic tissue scaffolds, mediated differentiation of stem cells, and silicon nanoneedles for drug delivery
• Highlights the use of silicon nanowires for detection and sensing

Materials scientists and biomedical engineers in academia and research, interested in nanobiomaterials, optical materials and associated biomedical devices/applications