Selected Topics in the History of Biochemistry Personal Recollections. I.
Preface to Volume 35
Contributors to this volume
List of Plates
Chapter 1. The Isolation of Cori-Ester, "The Saint Louis Gateway" to a First Approach of a Dynamic Formulation of Macromolecular Biosynthesis
The Coris in Post-World War I Europe
The Coris in the U.S.A.
Research at Washington University, School of Medicine
The Discovery of Cori-Ester and the Concept of Phosphorolysis
Polysaccharide Synthesis in Vitro
Isolation of Crystalline Muscle Phosphorylase Catalyzing Amylose Synthesis
Phosphorylases α and β and their Role in Metabolic Regulation
Regulation of Phosphorylase in Resting and Contracting Muscle
1947 Nobel Prize for Physiology and Medicine
The Effect of Hormones on Carbohydrate Metabolism in Vitro
Personal Data from Later Years
Chapter 2. The Discovery of Sugar Nucleotides
The Discovery of Sugar Nucleotides
1948-49 Glucose Diphosphate
1953-55 UDP-Glucuronic Acid
1953 Biosynthesis of Disaccarides
Chapter 3. The Road to Ion-Coupled Membrane Processes
A Year with Fritz Lipmann
A Decade with Carl Cori
Metabolite Regulation of Glucolysis
A Regulatory Site for Glucose-6-Phosphate
Toward the Mechanism of Glucose Active Trans
Selected Topics in the History of Biochemistry: Personal Recollections, I presents selected topics in the history of biochemistry based on the authors' personal recollections. These topics range from the isolation of Cori ester and the discovery of sugar nucleotides to the work of Frederick Gowland Hopkins (1861-1947). Ion-coupled membrane processes are also discussed, along with fructose and fructose-2,6-bisphosphateas well as lysosomes and glycogen.
Comprised of 12 chapters, this volume begins with the discovery of Cori ester and the concept of phosphorolysis before turning to the discovery of sugar nucleotides and research on ion-coupled membrane processes. The reader is then introduced to studies of fructose, fructose-2,6-bisphosphate, lysosomes, and glycogen; the contributions of Frederick Gowland Hopkins in biochemistry; and a short autobiography of Juda Hirsch Quastel, with emphasis on his research work on the concept of active centers as a possible explanation of enzyme action and his investigation of the effects of malonic acid and substituted malonic acids on bacterial dehydrogenases. The remaining chapters focus on a biochemist's approach to autopharmacology; the early development of modern protein chemistry in Uppsala, Sweden; and the biographies of two Russian scientists, A. N. Bach and Sergei E. Severin.
This monograph will be of interest to students, practitioners, and researchers in the field of biochemistry.
- © Elsevier Science 1983
- 1st January 1983
- Elsevier Science
- eBook ISBN:
- Hardcover ISBN:
Swiss Institute of Technology, ETH-Zentrum, Zürich, Switzerland