Chapter headings. Epoxidation of alkenes (M. Liu). Oxidation not involving epoxidation (J. Eames, M. Watkinson). Reactions involving metallocarbenes (D.M. Hodgson et al). Phase-transfer reactions (B. Lygo). Additions to carbonyl compounds (A.S. Franklin). Conjugate addition reactions (N.C.O. Tomkinson). Combinatorial approaches to asymmetric catalysis (A. Merritt). Enantioselective cycloaddition reactions (M.C. Willis). Palladium catalysed coupling reactions (C. Frost). Index
To date, the second edition of the Rodd's series consists of 71 volumes and over 30,000 pages.
Rodd's Chemistry of Carbon Compounds is continuing with a short series of topical volumes on emerging subjects that are not covered in detail in the main volumes. The first two topical volumes will cover organic electrochemistry and asymmetric catalysis.
Asymmetric synthesis initiated by metal catalysts is, of course, not a new topic and asymmetric reduction and epoxidation of alkenes, in particular, are major subject areas covered widely in the Supplements to the 2nd Edition of Rodd's Chemistry of the Carbon Compounds. However, there has been a huge increase in the use of asymmetrically catalysed reactions in other areas in the last five years or so, and this is why this subject has been specially selected to form the content of a Topical Volume.
The book does not dwell at length upon topics of great importance such as Sharpless epoxidation, or upon the control of stereochemistry through catalytic reduction of double bonds. These subjects have been exhaustively surveyed elsewhere. Instead it concentrates upon those topics that appear to be 'up and coming'. Only time can tell if all will be adopted as widely and successfully as their predecessors, but it now seems clear that chemists have at their disposal an ever increasing and formidable array of methods to effect total topological control of even the most complex target molecule.
This book, written by some of the best young chemists, concentrating upon work in their own subject areas, provides a snap shot of the current 'state of play' in this a key test of their scientific ingenuity.
In the Cumulative Index will be found the entire contents of the 2nd edition and both of the supplements, together with a list of main titles and chapter headings for each volume. This index will enable the reader to make bet
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- 12th November 2001
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