Schizophrenia

A Life-Course Developmental Perspective

1st Edition - August 28, 1991
Editor: Elaine F. Walker
Language: English
eBook ISBN:
9 7 8 - 1 - 4 8 3 2 - 2 0 5 3 - 6

Schizophrenia: A Life-Course Developmental Perspective covers research findings and ideas concerning the entire life course of schizophrenia. The book discusses research on… Read more

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Schizophrenia: A Life-Course Developmental Perspective covers research findings and ideas concerning the entire life course of schizophrenia. The book discusses research on life-span development in schizophrenia; the genetic and perinatal factors in the etiology of schizophrenia; as well as the neurobehavioral development of infants at risk for schizophrenia. The text also describes the early social and affective development in schizophrenic offspring; the clinical presentation, onset, early developmental patterns, course, and treatment of childhood-onset schizophrenia; and the prediction of psychiatric disorders in late adolescence. The cognitive and linguistic functions of adolescent children at risk for schizophrenia; longitudinal studies of premorbid development of adult schizophrenics; and the ontogenetic implications of sex differences in schizophrenia are also considered. The book further tackles emotion and attachment in families of schizophrenics; late-onset schizophrenia; and the development of liability to schizophrenia. The text then encompasses the developmental trajectories in schizophrenia. Psychiatrists, psychologists, and people working on the research about schizophrenia will find the book invaluable.

Contributors

Preface

1 Research on Life-Span Development in Schizophrenia

Impediments to the Study of the Life Course of Schizophrenia

Methodological Approaches to Longitudinal Research on Schizophrenia

Summary

References

Part I Perinatal Factors and Infancy

2 Genetic and Perinatal Factors in the Etiology of Schizophrenia

Introduction

The Copenhagen High-Risk Study

A Research Framework: Gene-Environment Interaction

An Empirical Test

Conclusions

References

3 Neurobehavioral Development of Infants at Risk for Schizophrenia: A Review

Overview of Existing Studies

Neonatal Behavior

Postneonatal Behavior

Relation of Other Biological and Social Factors to Infant Behavior

Prediction from Infancy to Later Behavior

Summary

References

4 Early Social and Affective Development in Schizophrenic Offspring

Evidence for Social and Emotional Competence: Social Interaction

Evidence for Social and Emotional Competence: Clinical and Diagnostic Assessments

Quality of Parenting by Schizophrenics and Its Role in Children's Social and Affective Development

Conclusions

References

Part II Childhood and Adolescence

5 Childhood-Onset Schizophrenia: Developmental Perspectives on Schizophrenic Disorders

Clinical Presentation

Onset, Precursor States, and Early Symptom Development

Clinical Heterogeneity

Course

Treatment

The Search for Etiological Pathways

Conclusions

References

6 The Prediction of Psychiatric Disorders in Late Adolescence

The New York High-Risk Project

Longitudinal Analyses of Attention

Early Attentional Deviance and Adolescent Adjustment

Summary

References

7 Cognitive and Linguistic Functions of Adolescent Children at Risk for Schizophrenia

Study of Language and Cognition in the High-Risk Paradigm

Specific Content Areas Investigated in Adolescents

Consistency of Deviance across Measures

Early Attention Deficits as a Predictor of Later Maladjustment

Profile of Performance during the Adolescent Risk Period

Conclusions

References

8 Longitudinal Studies of Premorbid Development of Adult Schizophrenics

Dated Conceptions of the Longitudinal Course of Schizophrenic Disorders

Contemporary Studies of Developmental Precursors, Prognostic Signs, and Outcome

Conclusions

The Most Promising Leads for Further Research on Premorbid Development

References

Part III Adulthood: The Onset and Course of Clinical Symptoms

9 Ontogenetic Implications of Sex Differences in Schizophrenia

Premorbid Development

Onset and First Hospital Admission Age

Clinical Picture at Onset-First Admission

Response to Treatment

Ontogenetic Processes

Future Directions

References

10 Emotion and Attachment in Families of Schizophrenics: The Struggle for Recovery

Expressed Emotion

Family-Based Intervention Studies

Yale Psychiatric Institute Family Study

Concluding Remarks

References

11 Late-Onset Schizophrenia

Historical Perspectives

Epidemiology

Clinical Picture

Etiology of Late-Onset Schizophrenia

Differential Diagnosis

Course and Prognosis

Treatment

Conclusions

References

12 Aging and Schizophrenia: Plasticity, Reversibility, and/or Compensation

Introduction

Biological Aging

Long-Term Outcome of Schizophrenia

New Concepts in Adult Development

Late-Onset Schizophrenia

Discussion

References

Part IV Developmental Conceptualizations of Schizophrenia

13 The Development of Liability to Schizophrenia: Early and Late Developmental Models

Early versus Late Developmental Models of Schizophrenic Liability

Early Childhood Abnormalities among Preschizophrenic Subjects

Inferred Early Abnormalities among Preschizophrenic Patients

Early Environmental Insults among Preschizphrenic Patients

An Alternative Hypothesis: A Late Developmental Genetic Model

Conclusions

References

14 Developmental Trajectories in Schizophrenia: Elucidating the Divergent Pathways

Sources of Variability among Patients

Neurodevelopmental Models of Schizophrenia

An Archival-Observational Approach to Research on the Development of Schizophrenia

Conclusions

References

Index

List of Previous Volumes