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Routes of Drug Administration covers topics about parenteral and enteral routes of drug administration. The book discusses the anatomy and physiology of administration sites; the formulation and design of delivery systems; and other relevant aspects of biopharmaceutics. The text describes pulmonary delivery, nasal, buccal, and transdermal routes of administration for systemic delivery, as well as a number of systems for more localized therapy with antibiotics. Innovative methods of antibiotic administration, such as continuous and intermittent infusion, endotracheal installation, aerosol delivery, antibiotic-impregnated catheters, antibiotic-containing bone cement, and beads, are also considered. Senior undergraduate and postgraduate students in pharmacy, medicine, nursing and allied health sciences and practitioners in these fields, as well as other professionals concerned with the preparation and administration of medicines and the monitoring of drug therapy will find the book useful.
List of Contributors
1 Nasal Drug Delivery
Assessment of Nasal Absorption
Drug Absorption Across the Nasal Mucosa
Nasal Drug Delivery Systems
Implications of Nasal Drug Delivery
2 Buccal and Sublingual Delivery of Drugs
Anatomy of the Oral Cavity
Physiology of Drug Absorption from the Oral Cavity
Drugs Given Buccally or Sublingually
Experimental Aspects of Sublingual and Buccal Drug Delivery
3 Drug Delivery to the Respiratory Tract
Respiratory Tract Morphology and Physiology
Diseases of the Lung
Chemotherapy of Respiratory Diseases
Fate of Compounds Administered to the Respiratory Tract
Generation of Therapeutic Aerosols
Particle Size Analysis of Therapeutic Aerosols
4 Transdermal Drug Delivery
Skin Structure and Barrier Properties
Development of Therapeutic Systems
Marketed Transdermal Systems
5 Innovative Methods of Antibiotic Administration
Continuous versus Intermittent Infusion
Endotracheal or Aerosolized Instillation of Antimicrobials
Antibiotic-Impregnated Bone Cement
- No. of pages:
- © Butterworth-Heinemann 1990
- 24th August 1990
- eBook ISBN:
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