Robbins & Cotran Pathologic Basis of Disease
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Readable and highly illustrated, Robbins and Cotran Pathologic Basis of Disease, 10th Edition presents an in-depth, state-of-the-art overview of human diseases and their cellular and molecular basis. This best-selling text delivers the latest, most essential pathology knowledge in a readable, interesting manner, ensuring optimal understanding of the latest basic science and clinical content. More than 1,000 high-quality photographs and full-color illustrations highlight new information in molecular biology, disease classifications, new drugs and drug therapies, and much more. This superb learning package also includes an enhanced eBook with a full complement of ancillary content on Student Consult.
Table of Contents
- Cover image
- Title page
- Table of Contents
- Endsheet
- Copyright
- Dedication
- Contributors
- Preface
- Acknowledgments
- Contents
- Chapter 1: The Cell as a Unit of Health and Disease
- The Genome
- Cellular Housekeeping
- Cellular Metabolism and Mitochondrial Function
- Cellular Activation
- Growth Factors and Receptors
- Extracellular Matrix
- Maintaining Cell Populations
- Chapter 2: Cell Injury, Cell Death, and Adaptations
- Introduction to Pathology
- Overview of Cellular Responses to Stress and Noxious Stimuli
- Reversible Cell Injury
- Cell Death
- Mechanisms of Cell Injury
- Clinicopathologic Correlations: Selected Examples of Cell Injury and DEATH
- Adaptations of Cellular Growth and Differentiation
- Intracellular Accumulations
- Pathologic Calcification
- Cellular Aging
- Chapter 3: Inflammation and Repair
- Overview of Inflammation: Definitions and General Features
- Acute Inflammation
- Chronic Inflammation
- Systemic Effects of Inflammation
- Tissue Repair
- Chapter 4: Hemodynamic Disorders, Thromboembolic Disease, and Shock
- Edema and Effusions
- Hyperemia and Congestion
- Hemostasis, Hemorrhagic Disorders, and Thrombosis
- Embolism
- Infarction
- Shock
- Chapter 5: Genetic Disorders
- Genes and Human Diseases
- Mendelian Disorders
- Complex Multigenic Disorders
- Chromosomal Disorders
- Single-Gene Disorders With Nonclassic Inheritance
- Molecular Genetic Diagnosis
- Acknowledgment
- Chapter 6: Diseases of the Immune System
- The Normal Immune Response
- Hypersensitivity: Immunologically Mediated Tissue Injury
- Autoimmune Diseases
- Rejection of Tissue Transplants
- Immunodeficiency Diseases
- Amyloidosis
- Chapter 7: Neoplasia
- Nomenclature
- Characteristics of Benign and Malignant Neoplasms
- Epidemiology of Cancer
- Molecular Basis of Cancer: Role of Genetic and Epigenetic Alterations
- Carcinogenic Agents and Their Cellular Interactions
- Clinical Aspects of Neoplasia
- Chapter 8: Infectious Diseases
- General Principles of Microbial Pathogenesis
- Viral Infections
- Bacterial Infections
- Fungal Infections
- Parasitic Infections
- Sexually Transmitted Infections
- Emerging Infectious Diseases
- Special Techniques for Diagnosing Infectious Agents
- Chapter 9: Environmental and Nutritional Diseases
- Health Effects of Climate Change
- Toxicity of Chemical and Physical Agents
- Environmental Pollution
- Occupational Health Risks: Industrial and Agricultural Exposures
- Effects of Alcohol
- Injury by Therapeutic Drugs and Drugs of Abuse
- Injury by Physical Agents
- Nutritional Diseases
- Chapter 10: Diseases of Infancy and ChildhoodaaThe prior contributions of Dr. Anirban Maitra to this chapter are gratefully acknowledged.
- Congenital Anomalies
- Prematurity and Fetal Growth Restriction
- Perinatal Infections
- Fetal Hydrops
- Inborn Errors of Metabolism and Other Genetic Disorders
- Sudden Infant Death Syndrome
- Tumors and Tumorlike Lesions of Infancy and Childhood
- Chapter 11: Blood Vessels
- Vascular Structure and Function
- Vascular Anomalies
- Vascular Wall Response to Injury
- Hypertensive Vascular Disease
- Arteriosclerosis
- Atherosclerosis
- Aneurysms and Dissection
- Vasculitis
- Disorders of Blood Vessel Hyperreactivity
- Veins and Lymphatics
- Vascular Tumors
- Pathology of Vascular Intervention
- Chapter 12: The Heart
- Cardiac Structure and Specializations
- Overview of Cardiac Pathophysiology
- Heart Failure
- Cardiac Development
- Congenital Heart Disease
- Ischemic Heart Disease
- Arrhythmias
- Hypertensive Heart Disease
- Valvular Heart Disease
- Cardiomyopathies
- Pericardial Disease
- Tumors of the Heart
- Cardiac Transplantation
- Cardiac Devices
- Chapter 13: Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus
- Normal Hematopoiesis
- Disorders of White Cells
- Spleen
- Thymus
- Chapter 14: Red Blood Cell and Bleeding Disorders
- Anemias
- Polycythemia
- Bleeding Disorders: Hemorrhagic Diatheses
- Chapter 15: The Lung
- Congenital Anomalies
- Atelectasis (Collapse)
- Pulmonary Edema
- Acute Lung Injury and Acute Respiratory Distress Syndrome (Diffuse Alveolar Damage)
- Obstructive and Restrictive Lung Diseases
- Obstructive Lung Diseases
- Chronic Diffuse Interstitial (Restrictive) Diseases
- Diseases of Vascular Origin
- Pulmonary Infections
- Lung Transplantation
- Tumors
- Pleura
- Chapter 16: Head and Neck
- Oral Cavity
- Upper Airways
- Ears
- Neck
- Salivary Glands
- Chapter 17: The Gastrointestinal Tract
- Congenital Abnormalities
- Esophagus
- Stomach
- Small Intestine and Colon
- Peritoneal Cavity
- Congenital Abnormalities
- Esophagus
- Stomach
- Small Intestine and Colon
- Peritoneal Cavity
- Chapter 18: Liver and Gallbladder
- The Liver and Bile Ducts
- Gallbladder
- Chapter 19: The Pancreas
- Congenital Anomalies
- Pancreatitis
- Nonneoplastic Cysts
- Neoplasms
- Chapter 20: The Kidney
- Clinical Manifestations of Renal Diseases
- Glomerular Diseases
- Tubular and Interstitial Diseases
- Vascular Diseases
- Congenital and Developmental Anomalies
- Cystic Diseases of the Kidney
- Urinary Tract Obstruction (Obstructive Uropathy)
- Urolithiasis (Renal Calculi, Stones)
- Neoplasms of the Kidney
- Chapter 21: The Lower Urinary Tract and Male Genital System
- The Lower Urinary Tract
- The Male Genital Tract
- Chapter 22: The Female Genital Tract
- Vulva
- Vagina
- Cervix
- Body of Uterus and Endometrium
- Ovaries
- Gestational and Placental Disorders
- Chapter 23: The Breast
- Disorders of Development
- Clinical Presentations of Breast Disease
- Inflammatory Disorders
- Benign Epithelial Lesions
- Carcinoma of the Breast
- Stromal Tumors
- Other Malignant Tumors of the Breast
- Chapter 24: The Endocrine System
- Pituitary Gland
- Thyroid Gland
- Parathyroid Glands
- The Endocrine Pancreas
- Adrenal Glands
- Multiple Endocrine Neoplasia Syndromes
- Pineal Gland
- Chapter 25: The Skin
- The Skin: More Than a Mechanical Barrier
- Disorders of Pigmentation and Melanocytes
- Benign Epithelial Tumors
- Adnexal (Appendage) Tumors
- Premalignant and Malignant Epidermal Tumors
- Tumors of the Dermis
- Tumors of Cellular Migrants to the Skin
- Disorders of Epidermal Maturation
- Acute Inflammatory Dermatoses
- Chronic Inflammatory Dermatoses
- Blistering (Bullous) Diseases
- Disorders of Epidermal Appendages
- Panniculitis
- Infection
- Chapter 26: Bones, Joints, and Soft Tissue Tumors
- Bone
- Joints
- Soft Tissue Tumors
- Chapter 27: Peripheral Nerves and Skeletal Muscles
- Diseases of Peripheral Nerves
- Diseases of the Neuromuscular Junction
- Diseases of Skeletal Muscle
- Peripheral Nerve Sheath Tumors
- Chapter 28: The Central Nervous System
- Cellular Pathology of the Central Nervous System
- Cerebral Edema, Hydrocephalus, Raised Intracranial Pressure, and Herniation
- Malformations and Developmental Disorders
- Perinatal Brain Injury
- Trauma
- Cerebrovascular Disease
- Infections
- Demyelinating Diseases
- Neurodegenerative Diseases
- Genetic Metabolic Diseases
- Toxic and Acquired Metabolic Diseases
- Tumors
- Acknowledgment
- Chapter 29: The Eye
- Orbit
- Eyelid
- Conjunctiva
- Sclera
- Cornea
- Anterior Segment
- Uvea
- Retina and Vitreous
- Optic Nerve
- The End-Stage Eye: Phthisis Bulbi
- Index
Product details
- No. of pages: 1392
- Language: English
- Copyright: © Elsevier 2020
- Published: May 18, 2020
- Imprint: Elsevier
- Hardcover ISBN: 9780323531139
- eBook ISBN: 9780323609937
About the Authors
Vinay Kumar
Vinay Kumar, MBBS, MD, FRCPath, Alice Hogge and Arthur A. Baer Distinguished Service Professor of Pathology, Biologic Sciences Division and the Pritzker Medical School, The University of Chicago, Chicago, Illinois, USA
Affiliations and Expertise
Alice Hogge and Arthur A. Baer Distinguished Service Professor of Pathology, Biologic Sciences Division and the Pritzker Medical School, The University of Chicago, Chicago, Illinois, USA
Abul Abbas
Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California
Affiliations and Expertise
Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California
Jon Aster
Jon C. Aster, MD, PhD, Professor of Pathology, Harvard Medical School; Brigham and Women's Hospital, Boston, Massachusetts
Affiliations and Expertise
Professor, Department of Pathology, Harvard Medical School; Brigham and Women's Hospital, Boston, Massachusetts
Ratings and Reviews
Latest reviews
(Total rating for all reviews)
Rehana R. Sat Mar 12 2022
Amazing!
I'm currently using the 10th edition of this masterpiece book .It is one of the most valuable books for medical students. Being a radiology student I give 5 stars to this book.hat's off to the authors!