RNA - Ligand Interactions, Part A: Structural Biology Methods

RNA - Ligand Interactions, Part A: Structural Biology Methods

1st Edition - April 14, 2000

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  • Editors-in-Chief: John Abelson, Melvin Simon
  • eBook ISBN: 9780080496740

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RNA-Ligand Interactions, Part A focuses on structural biology methods. Major topics covered include semisynthetic methodologies (RNA synthetic methods and derivatization of RNA); RNA structure determination (X-ray crystallography, NMR, EM); techniques for monitoring RNA conformation and dynamics (solution methods and electrophoretic and spectroscopic methods); and modeling tertiary structure: Part B, its companion Volume 318 of Methods in Enzymology, focuses on molecular biology methods.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the Series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.


Biochemists, molecular biologists, geneticists, cell biologists, and microbiologists.

Table of Contents

  • Semisynthetic Methodologies:
    RNA Synthetic Methods.
    Derivation of RNA.
    RNA Structure Determination:
    X-Ray Crystallography.
    Nuclear Magnetic Resonance Spectroscopy.
    Electron Microscopy.
    Techniques for Monitoring RNA Conformation and Dynamics:
    Solution Methods.
    Electrophoretic and Spectroscopic Methods.
    Modeling Tertiary Structure.
    Author Index.
    Subject Index.

Product details

  • No. of pages: 549
  • Language: English
  • Copyright: © Academic Press 2000
  • Published: April 14, 2000
  • Imprint: Academic Press
  • eBook ISBN: 9780080496740

About the Editors in Chief

John Abelson

Affiliations and Expertise

California Institute of Technology, Division of Biology, Pasadena, U.S.A.

Melvin Simon

Affiliations and Expertise

The Salk Institute, La Jolla, CA, USA

About the Serial Volume Editor

Daniel Celander

Affiliations and Expertise

Loyola University, Chicago, Illinois, U.S.A.

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