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Retinoids, Part B - 1st Edition - ISBN: 9780121820916, 9780080883076

Retinoids, Part B, Volume 190

1st Edition

Cell Differentiation and Clinical Applications

Editors in Chief: John Abelson Melvin Simon
Serial Volume Editor: Helmut Sies
Hardcover ISBN: 9780121820916
eBook ISBN: 9780080883076
Imprint: Academic Press
Published Date: 28th December 1990
Page Count: 488


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Table of Contents

Cell Differentiation:
Normal Cells:
A.M. Timmers and W.J. De Grip, Analysis of Visual Cycle by Short-Term Incubation of Isolated Retinal Pigment Epithelium Cells.
G.J. Giudice and E. Fuchs, Vitamin A-Mediated Regulation of Keratinocyte Differentiation.
M. Ponec and A. Weerheim, Retinoids and Lipid changes in the Keratinocytes.
A.M. Jetten, M.A. George, and J.I. Rearick, Down-Regulation of Squamous Cell-Specific Markers by Retinoids: Transglutaminase Type I and Cholesterol Sulfotransferase.
H.F.J. Hendriks, A. Brouwer, and D.L. Knook, Isolation, Purification, and Characterization of Liver Cell Types.
R. Blomhoff and T. Berg, Isolation and Cultivation of Hepatic Stellate Cells.
A.F. Karl and M.D. Griswold, Sertoli Cells of the Testis: Preparation of Cell Cultures and Effects of Retinoids.
L.M. Milstone, Measurement of Retinoid Effects on Epidermal Renewal.
L.M. De Luca, S. Adamo, and S. Kato, Retinoids and Cell Adhesion. L.M. De Luca, D.R. Roop, and F.L. Huang, Retinoids and Cell Adhesion.
Cell Lines:
R. Lotan, D. Lotan, P.G. Sacks, Inhibition of Tumor Cell Growth by Retinoids.
A.L. Darrow, R.J. Rickles, and S. Strickland, Maintenance and Use of F9 Teratocarcinoma Cells.
T.R. Breitman, Studies of Growth and Differentiation of the Human Myeloid Leukemia Cell Line HL60.
L.J. Gudas, Assays for Expression of Genes Regulated by Retinoic Acid in Murine Teratocarcinoma Cell Lines.
S.-L. Fong and C.D.B. Bridges, Retinoid-Binding Proteins in Retinoblastoma Cells.
J.F. Grippo and M.I. Sherman, Analysis of Role of Retinoid-Binding Proteins in Embryonal Carcinoma Cells.
Tissues and Organ Culture:
J.C. Saari and D.L. Bredberg, Acyl CoA: Retinol Acyl Transferase and Lecithin: Retinol Acyl Transferase Activities in Bovine Retinal Pigment Epithelial Microsomes.
A. Vahlquist, H. Torma, O. Rollman, and E. Andersson, Determination of Natural and Synthetic Retinoids in Human Skin Samples by High-Performance Liquid Chromatography.
C.E. Brinckerhoff, Retinoids Modulate Extracellular Matrix by Controlling Expression of Collagenase: Rheumatoid Arthritis as Model
Retinoids as Morphogens and Teratology:
D.L. Stocum and M. Maden, Regenerating Limbs.
S.E. Wedden, C. Thaller, and G. Eichele, Targeted Slow Release of Retinoids into Chick Embryos.
H. Torma and A. Vahlquist, Biosynthesis of 3,4-Didehydroretinol and Fatty Acyl Esters of Retinol and 3,4-Didehydroretinol by organ Cultured Human Skin.
Cell Synopsis:
B. Amos and R. Lotan, Retinoid Sensitive Cells and Cell Lines.
Nutrition, Tissue and Immune Status, and Antioxidant Action:
J.E. Smith, Preparation of Vitamin A-Deficient Rats and Mice.
K.L. Simpson, Use of Food Composition Tables for Retinol and Provitamin A Carotenoid Content.
Tissue and Immune Status:
B.A. Underwood, Assessing Vitamin A Status in Human Populations.
D.A. Faherty and A. Bendich, Characterization of Immunomodulatory Activity of Retinoids.
K.M. Nauss, A.C. Ross, and S.S. Twining, Immunotrophic Methodology.
Antioxidant Action:
M. Hiramatsu and L. Packer, Antioxidant Activity of Retinoids.
V.M. Samokyszyn and L.J. Marnett, Inhibition of Microsomal Lipid Peroxidation by 13-cis-Retinoic Acid.
Pharmacokinetics, Pharmacology, and Toxicology:
R. Ehlert, H. Gollnick, G. Rinck, and C.E. Orfanos, Retinoids: An Overview of Pharmacokinetics and Therapeutic Value.
M.H. Green and J.B. Green, Experimental and Kinetic Methods for Studying Vitamin A Dynamics in Vivo.
D.M. Kochhar, Quantification in Embryo of Retinoic Acid Derived from Maternally Administered Retinol.
S.S. Shapiro and J. Hurley, Effect of Retinoids on Sebaceous Glands.
T.I. Doran and S.S. Shapiro, Retinoid Effects on Sebocyte Proliferation.
T. Kealey, Effects of Retinoids on Human Sebaceous Glands Isolated by Shearing.
G.F. Bryce and S.S. Shapiro, Retinoid Effects on Photodamaged Skin.
G.L. Grove, M.J. Grove, and J.J Leyden, Effects of Topical Retinoids on Photoaged Skin as Measured by Optical Profilometry.
L.H. Kligman, Retinoid Effects on Photodamaged Skin.
K. Teelmann, Testing of Retinoids for Systemic and Topical use in Human Psoriasis and Other Disorders of Keratinization (The Mouse Papilloma Test).
R.C. Moon and R.G. Mehta, Cancer Chemoprevention by Retinoids in Animal Models.
C.C. Willhite and S.A. Book, Utility of Disposition Data in Evaluating Retinoid Developmental Toxicity.
A. Kistler and W.B. Howard, Testing of Retinoids: Mechanistic Studies.
A. Kistler and W.B. Howard, Testing of Retinoids for Teratogenicity in Vitro Use of the Micromass Limb Bud Cell Culture.
A. Kistler and W.B. Howard, Testing of Retinoids for Teratogenicity in Vivo.
H. Nau, Correlation of Transplacental and Maternal Pharmacokinetics of Retinoids during Organogenesis with Teratogenicity.
Author Index.
Subject Index.


The methods in Volumes 189 and 190 apply to the use of retinoids in basic research in molecular, cellular, and development biology and in clinical medicine.


Biochemists, nutritionists, molecular biologists, cell biologists, pharmacologists, toxicologists, oncologists, and immunologists.


No. of pages:
© Academic Press 1990
28th December 1990
Academic Press
Hardcover ISBN:
eBook ISBN:


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About the Editors in Chief

John Abelson

John Abelson

Affiliations and Expertise

California Institute of Technology, Division of Biology, Pasadena, U.S.A.

Melvin Simon

Melvin Simon

Affiliations and Expertise

The Salk Institute, La Jolla, CA, USA

About the Serial Volume Editor

Helmut Sies

Helmut Sies

Helmut Sies, MD, PhD (hon), studied medicine at the universities of Tübingen, Munich, and Paris. He was the professor and chair of the Institute for Biochemistry and Molecular Biology I at Heinrich-Heine-University Düsseldorf, Germany, where he is now professor emeritus. He is a member of the German National Academy of Sciences Leopoldina and was the president of the North Rhine-Westphalian Academy of Sciences and Arts. He was named ‘Redox Pioneer’; was the president of the Society for Free Radical Research International (SFRRI). Helmut Sies introduced the concept of “Oxidative Stress” in 1985, and was the first to reveal hydrogen peroxide as a normal constituent of aerobic cell metabolism. His research interests comprise redox biology, oxidants, antioxidants, micronutrients.

Affiliations and Expertise

Heinrich-Heine-University Düsseldorf, Germany