Retinal Pharmacotherapy

1st Edition

Print ISBN: 9781437706031
eBook ISBN: 9781455706792
Imprint: Saunders
Published Date: 26th February 2010
Page Count: 408


Retinal Pharmacotherapy is the first comprehensive book devoted to pharmacologic agents and their rationale and mechanisms of action in selected retinal and uveitic diseases. Drs. Quan Dong Nguyen, Eduardo Buchele Rodrigues, Michel Eid Farah, and William F. Mieler lead an international team of expert contributors to present up-to-date knowledge of new drugs on the market, the science behind the drugs, evidence of how the drugs work, and the reasons why they are effective or not. This user-friendly, all-in-one reference provides you with easy access to practical information on the effective and appropriate use of pharmacologic agents in the management of retinal diseases.

Key Features


  • Covers all new and existing retinal drugs to keep you current in this expanding area of the treatment of retinal diseases.
  • Discusses the background behind retinal drugs and the various pathways of how they work so you can make thoroughly informed clinical decisions.
  • Presents 400 color photographs and line drawings that illustrate disease appearance before and after treatment and clarify difficult key concepts.
  • Features contributors from Europe, North America, South America, the Middle East, Asia, and Australia for an international approach.
  • Identifies and emphasizes key points clearly in each chapter to improve comprehension and make finding information easier.

Table of Contents

1 Evolving Knowledge in Pharmacologic

Section 1: Basic Sciences in Retina

2 Retinal Anatomy and Pathology

3 Retinal Biochemistry, Physiology and
Cell Biology

4 Ocular Angiogenesis: Vascular Endothelial
Growth Factor and Other Factors

5 Ocular Immunity and Inflammation

6 Complement Activation and Inhibition in
Retinal Disease

7 Genetics of Retinal Disease

Section 2: Animal Models and Routes for
Retinal Drug Delivery

8 Vitamins and Supplements for Age-Related
Macular Degeneration

9 Ocular Pharmacokinetic, Drug Bioavailability and Intraocular Drug Delivery Systems

0 Routes for Drug Delivery to the Eye and Retina: Intravitreal Injections and Vitrectomy

11 Routes for Drug Delivery: Topical, Transscleral, Suprachoroidal, and Intravitreal
Gas-Phase Nanoparticles

12 Routes for Drug Delivery: Sustained-Release

13 Microspheres and Nanotechnology for
Drug Delivery

14 Thermo-sensitive Hydrogels

15 Retina and Ocular Toxicity to Ocular Application
of Drugs

16 Retinal Toxicity of Systemic and Topical

Section 3: Retinal Diseases Amenable to Pharmacotherapy

17 Non-neovascular Age-Related Macular

18 Neovascular Age-Related Macular Degeneration

19 Diabetic Retinopathy and Diabetic
Macular Edema

20 Retinal Vein Occlusion

21 Retinal Detachment and Proliferative

22 Posterior Uveitis

23 Choroidal Neovascularization Secondary
to Inflammation, Infection, and Myopia

24 Ocular Infection: Endophthalmitis

25 Retinopathy of Prematurity

26 Idiopathic Macular Telangiectasia

27 Neovascular Glaucoma

28 Retinal Hereditary and Degenerative /
Dystrophic Diseases (


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