Research Surgery and Care of the Research Animal

Methods of Animal Experimentation, Volume VII: Research Surgery and Care of the Research Animal, Part C is a collection of papers that deals with methods used in animal experiments concerning surgical approaches to certain organ systems such as the maxillofacial and skin systems. This collection deals with surgery involving the oral and maxillofacial, ophthalmic, skin systems, as well as research on canine immune systems and applications of microsurgery and laser surgery. One paper discusses orthognathic surgery including temporomandibular joint and dental implants. Another paper describes corneal procedures, lens extraction, and intraocular lenses. In discussing skin experimental surgery, the author explains procedures in flap anatomy, surgical healing, skin grafting, and burn treatment. The techniques in studying the immune systems of dogs include procedures dealing with peripheral blood, bone marrow, reactive cells, and tissues. Other authors explain the application of microsurgery to laboratory research including the equipment and techniques used, as well as the general principles of tissue transplantation into the animal's central nervous system. Another author discusses the use of lasers and special considerations such as laser restrictions and instrumentation. This book will be appreciated by laboratory assistants and scientists dealing with test animals, by veterinarians, and by researchers designing animal and medical experiments.

Foreword Preface Chapter 1 Animal Research Models in Oral and Maxillofacial Surgery I. Introduction II. Orthognathic Surgery III. Experimental Fractures IV. Temporomandibular Joint V. Bone Grafting VI. Dental Implants VII. Osteomyelitis VIII. Tooth Transplantation IX. Alveolar Cleft Grafts X. Summary References Chapter 2 Ophthalmic Surgery on Laboratory Animals I. Introduction II. Corneal Procedures III. Lens Extraction and Intraocular Lenses IV. Intraocular Injections V. Vitrectomy VI. Use of Surgical Models in Glaucoma Research VII. Lasers in Ophthalmic Surgery VIII. Adjunctive Medications and Devices in Intraocular Surgery References Chapter 3 Experimental Skin Surgery I. Introduction II. Flap Anatomy and Physiology III. Microsurgery IV. Wound Healing as It Relates to Skin Surgery V. Skin Grafting VI. Burns VII. Summary References Chapter 4 Experimental Techniques Used to Study the Immune System of Dogs and Other Large Animals I. Introduction II. Immunologically Reactive Tissue III. Immunocompetence and Immunosuppression IV. Experimental Techniques for Peripheral Blood V. Experimental Techniques for Bone Marrow VI. Procedures Involving Other Immunologically Reactive Cells and Tissues VII. Procedures for Establishing and Using Experimental Immune Models References Chapter 5 The Application of Microsurgery to Laboratory Research I. Introduction and History II. Equipment III. Techniques IV. Summary and Future Laboratory Microsurgery References Chapter 6 Neurotransplantation I. History and Rationale II. General Principles of Transplantation into the Nervous System III. Model Systems for Transplantation IV. Immunology of CNS Transplants V. Vascularity of Neural Transplants VI. Co