Research Surgery and Care of the Research Animal

Research Surgery and Care of the Research Animal

Surgical Approaches to the Organ Systems

1st Edition - September 28, 1989

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  • Editors: William I. Gay, James E. Heavner
  • eBook ISBN: 9781483259727

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Methods of Animal Experimentation, Volume VII: Research Surgery and Care of the Research Animal, Part C is a collection of papers that deals with methods used in animal experiments concerning surgical approaches to certain organ systems such as the maxillofacial and skin systems. This collection deals with surgery involving the oral and maxillofacial, ophthalmic, skin systems, as well as research on canine immune systems and applications of microsurgery and laser surgery. One paper discusses orthognathic surgery including temporomandibular joint and dental implants. Another paper describes corneal procedures, lens extraction, and intraocular lenses. In discussing skin experimental surgery, the author explains procedures in flap anatomy, surgical healing, skin grafting, and burn treatment. The techniques in studying the immune systems of dogs include procedures dealing with peripheral blood, bone marrow, reactive cells, and tissues. Other authors explain the application of microsurgery to laboratory research including the equipment and techniques used, as well as the general principles of tissue transplantation into the animal's central nervous system. Another author discusses the use of lasers and special considerations such as laser restrictions and instrumentation. This book will be appreciated by laboratory assistants and scientists dealing with test animals, by veterinarians, and by researchers designing animal and medical experiments.

Table of Contents

  • Foreword


    Chapter 1 Animal Research Models in Oral and Maxillofacial Surgery

    I. Introduction

    II. Orthognathic Surgery

    III. Experimental Fractures

    IV. Temporomandibular Joint

    V. Bone Grafting

    VI. Dental Implants

    VII. Osteomyelitis

    VIII. Tooth Transplantation

    IX. Alveolar Cleft Grafts

    X. Summary


    Chapter 2 Ophthalmic Surgery on Laboratory Animals

    I. Introduction

    II. Corneal Procedures

    III. Lens Extraction and Intraocular Lenses

    IV. Intraocular Injections

    V. Vitrectomy

    VI. Use of Surgical Models in Glaucoma Research

    VII. Lasers in Ophthalmic Surgery

    VIII. Adjunctive Medications and Devices in Intraocular Surgery


    Chapter 3 Experimental Skin Surgery

    I. Introduction

    II. Flap Anatomy and Physiology

    III. Microsurgery

    IV. Wound Healing as It Relates to Skin Surgery

    V. Skin Grafting

    VI. Burns

    VII. Summary


    Chapter 4 Experimental Techniques Used to Study the Immune System of Dogs and Other Large Animals

    I. Introduction

    II. Immunologically Reactive Tissue

    III. Immunocompetence and Immunosuppression

    IV. Experimental Techniques for Peripheral Blood

    V. Experimental Techniques for Bone Marrow

    VI. Procedures Involving Other Immunologically Reactive Cells and Tissues

    VII. Procedures for Establishing and Using Experimental Immune Models


    Chapter 5 The Application of Microsurgery to Laboratory Research

    I. Introduction and History

    II. Equipment

    III. Techniques

    IV. Summary and Future Laboratory Microsurgery


    Chapter 6 Neurotransplantation

    I. History and Rationale

    II. General Principles of Transplantation into the Nervous System

    III. Model Systems for Transplantation

    IV. Immunology of CNS Transplants

    V. Vascularity of Neural Transplants

    VI. Conclusions


    Chapter 7 Experimental Surgery Using Lasers

    I. Introduction

    II. Laser Physics

    III. Special Considerations

    IV. Laser-Tissue Interactions

    V. Animal Models for Surgical Applications of Lasers



Product details

  • No. of pages: 250
  • Language: English
  • Copyright: © Academic Press 1989
  • Published: September 28, 1989
  • Imprint: Academic Press
  • eBook ISBN: 9781483259727

About the Editors

William I. Gay

James E. Heavner

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