Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part A

Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part A

1st Edition - March 28, 2021

Write a review

  • Editor: Vijai Singh
  • eBook ISBN: 9780323853224
  • Hardcover ISBN: 9780323853217

Purchase options

Purchase options
DRM-free (PDF, EPub, Mobi)
Available
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order

Description

Reprogramming the Genome: Applications of CRISPR-Cas in Non-mammalian Systems, Part A presents a collation of chapters written by global, eminent scientists. CRISPR-Cas9 system is an RNA-mediated immune system of bacteria and archaea that protects from bacteriophage infections. It is one of the revolutionized technologies to uplift biology to the next stages. Chapters in this release include An Introduction and applications of CRISPR-Cas Systems, History, evolution and classification of CRISPR-Cas associated systems, CRISPR based bacterial genome editing and removal of pathogens, CRISPR based genome editing and removal of human viruses, CRISPR based development of RNA editing and diagnostic platform, and much more. Additional sections cover Genome engineering in insects for control of vector borne diseases, Development of insect cell line using CRISPR technology, CRISPRing protozoan parasites to better understand the biology of diseases, CRISPR based genome editing of Caenorhabditis elegans, and a variety of other important topics.

Key Features

  • Offers a basic understanding and clear picture of genome editing CRISPR-Cas systems in different organisms
  • Explains how to create an animal model for disease diagnosis/research and reprogram CRISPR for removal of virus, bacteria, fungi, protozoan, and many more
  • Discusses the advances, patents, applications, challenges and opportunities in CRISPR-Cas9 systems in basic sciences, biomedicine, virology, bacteriology, molecular biology, and many more

Readership

This book will be valuable sources of information for not only beginner in area of genome engineering area, but also researchers, students, scientists, clinicians, stakeholders, policy makers and practitioners and many more.

Table of Contents

  • 1. An introduction and use of the CRISPR-Cas systems
    Vijai Singh


    2. History, evolution and classification of CRISPR-Cas associated systems
    Nisheeth Agarwal and Radhika Gupta


    3. CRISPR based bacterial genome editing and removal of pathogens
    Ravi Jothi, Chandrasekar Karthika, Arumugam Kamaladevi, Lakkakula Satish, Shunmugiah Karutha Pandian and Shanmugaraj Gowrishankar


    4. CRISPR based genome editing and removal of human viruses
    Yuan-Chuan Chen


    5. CRISPR based development of RNA editing and the diagnostic platform
    Lakkakula Satish, Gunamalai Lavanya, Thirupathi Kasthuri, Aruchamy Kalaivaani, Sasanala Shamili, Muthuramalingam Pandian, Shanmugaraj Gowrishankar, Shunmugiah Karutha Pandian, Vijai Singh, Yaron Sitrit and Ariel Kushmaro


    6. CRISPR-based pathogenic fungal genome editing for control of infection and disease
    Takayuki Arazoe


    7. Genome engineering in insects for the control of vector borne diseases
    V. Edwin Hillary and S. Antony Ceasar

Product details

  • No. of pages: 242
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: March 28, 2021
  • Imprint: Academic Press
  • eBook ISBN: 9780323853224
  • Hardcover ISBN: 9780323853217

About the Serial Volume Editor

Vijai Singh

Dr Vijai Singh is an Associate Professor and Dean (Research & Innovation) at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He was an Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, India and also an Assistant Professor in the Department of Biotechnology at the Invertis University, Bareilly, India. Prior to that, he was a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He received his Ph.D. in Biotechnology (2009) from the National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India with a research focus on the development of molecular and immunoassays for diagnosis of Aeromonas hydrophila. His research interests are focused on design of a novel biosynthetic pathways for production of medically and industrially important biomolecules. Additionally, his laboratory focuses on development and implementation of CRISPR-Cas systems for genome editing, regulation and diagnosis. His laboratory is supported by projects from Government of India and industry. He has more than 10 years of research and teaching experience in synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has published 79 articles, 51 chapters, 15 books and 4 patents. He serves as an associate editor, editorial board member, and reviewer of several peer-reviewed journals. He is also a member of the Board of Study and Academic Council of Indrashil University and is the Member Secretary of the Institutional Biosafety Committee (IBSC) at the same University.

Affiliations and Expertise

Associate Professor and Dean (Research & Innovation) at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India.

Ratings and Reviews

Write a review

There are currently no reviews for "Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part A"