Relative Radiation Sensitivities of Human Organ Systems - 1st Edition - ISBN: 9780120354122, 9781483215686

Relative Radiation Sensitivities of Human Organ Systems

1st Edition

Advances in Radiation Biology, Vol. 12

Editors: John T. Lett Kurt I. Altman
eBook ISBN: 9781483215686
Imprint: Academic Press
Published Date: 19th March 1987
Page Count: 306
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Advances in Radiation Biology, Volume 12: Relative Radiation Sensitivities of Human Organ Systems covers articles on the response of selected human organ and tissue systems to exposure to ionizing radiation. The book presents articles on the relative radiosensitivities of the thymus, spleen, lymphohemopoietic systems, small and large intestines, oral cavity, larynx, pharynx, and esophagus. The text also includes articles on the relative radiation sensitivity of the integumentary system, as well as the relative radiosensitivity of the human lung and fetal tissues. The tolerance of the central and peripheral nervous system to therapeutic irradiation is also encompassed. Radiation biologists, oncologists, physicians, pediatricians, and medical students will find the book useful.

Table of Contents


Relative Radiosensitivities of the Thymus, Spleen, and Lymphohemopoietic Systems

I. Introduction

II. The Lymphoid Organs

III. Lymphocyte Sensitivity to Radiation

IV. Radiation Response of Hemopoietic Stem Cells

V. Radiation Response of Lymphoid Organs

VI. Therapy of Lymphohemopoietic Tissue and Application to Human Disease

VII. Late Effects of Human Therapeutic Irradiation

VIII. Summary and Conclusions


Relative Radiosensitivities of the Small and Large Intestine

I. Introduction

II. Stomach

III. Small Intestine

IV. Large Intestine

V. Conclusions and View into the Future


Relative Radiosensitivities of the Oral Cavity, Larynx, Pharynx, and Esophagus

I. Introduction

II. Mucosal Epithelial Tissues

III. Salivary Glands

IV. Teeth

V. Taste

VI. Bone, Cartilage, and Soft Tissues

VII. Esophagus


Relative Radiation Sensitivity of the Integumentary System: Dose Response of the Epidermal, Microvascular, and Dermal Populations

I. Introduction

II. Cell Kinetic Parameters and Morphological Considerations of Unirradiated Skin

III. Gross and Histologic Skin Changes Produced by Irradiation

IV. Clinical and Radiobiological Considerations: Skin Dose Response


Relative Radiosensitivity of the Human Lung

I. The Problem

II. Pulmonary Structure and Function

III. Cell Populations in the Lung

IV. Phases of Lung Response

V. Assays of Lung Damage in Humans and Experimental Animals

VI. Radiosensitivity of the Lung

VII. Whole versus Partial Lung Irradiation

VIII. Conclusions


Relative Radiosensitivity of Fetal Tissues

I. Introduction

II. Radiation-Produced Reproductive Effects in Animals and Man

III. Appropriateness of Animal Studies for Determining Human Intrauterine Radiation Risks

IV. The Risk of Intrauterine Irradiation in the Human and the Contribution of Animal Studies: Summary


Tolerance of the Central and Peripheral Nervous System to Therapeutic Irradiation

I. Introduction

II. Radiation Injury to the Brain

III. Radiation Injury to the Spinal Cord

IV. Radiation Injury to the Optic Nerves and Chiasm

V. Radiation Retinopathy

VI. Cranial and Peripheral Nerve Injury

VII. Summary




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© Academic Press 1987
Academic Press
eBook ISBN:

About the Editor

John T. Lett

Kurt I. Altman

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