Description

This compendium provides a concise and up-to-date assessment of critical recent issues related to erythroid biology. Developmental, epigenetic, methodological, biochemical, and clinical aspects are integrated to provide a powerful overview of their interrelationships and importance to the generation of the red cell. The excitement generated by these novel observations and the anticipation of future directions in studies of the red cell is a highlight of this volume.

Key Features

*The first comprehensive volume covering the breadth of the topic *The latest advancements that lead to novel directions in the study of red cells *An informative discussion of red cells as they relate to the essential oxygen-carrying component of the body

Readership

developmental biologists, molecular biologists, stem cell biologists, pediatric and adult hematologists

Table of Contents

1 Ontogeny of Erythropoiesis in the Mammalian Embryo Kathleen McGrath and James Palis 2 The Erythroblastic Island Deepa Manwani and James J Bieker 3 Epigenetic Control of Complex Loci During Erythropoiesis Ryan J. Wozniak and Emery H. Bresnick 4 The Role of the Epigenetic Signal, DNA Methylation, in Gene Regulation During Erythroid Development Gordon D. Ginder, Merlin N. Gnanapragasam, and Omar Y. Mian 5 Three-dimensional Organisation of Gene Expression in Erythroid Cells Wouter de Laat, Petra Klous, Jurgen Kooren, Daan Noordermeer, Robert-Jan Palstra, Marieke Simonis, Erik Splinter, Frank Grosveld 6. Iron Homeostasis and Erythropoiesis Diedra M. Wrighting and Nancy C. Andrews 7. The Effects of Nitric Oxide on Red Cell Development and Phenotype Vladan P. Èokiæ and Alan N. Schechter 8. Diamond Blackfan Anemia: A Disorder of Red Blood Cell Development Steven. R. Ellis and Jeffrey M. Lipton

Details

No. of pages:
227
Language:
English
Copyright:
© 2008
Published:
Imprint:
Academic Press
eBook ISBN:
9780080560946
Print ISBN:
9780123743664