(Section Headings): Use of Enzymes in Recombinant DNA Research. Enzymes Affecting the Gross Morphology of DNA: Topoisomerases Type I; Topoisomerases Type II. Proteins with Specialized Functions Acting at Specific Loci. New Methods for DNA Isolation, Hybridization, and Cloning. Analytical Methods for Gene Products. Mutagenesis: In Vitro and in Vivo. Author Index. Subject Index.