Receptors - 1st Edition - ISBN: 9780080231914, 9781483157962

Receptors

1st Edition

Proceedings of the 7th International Congress of Pharmacology, Paris, 1978

Editors: J. Jacob
eBook ISBN: 9781483157962
Imprint: Pergamon
Published Date: 1st January 1979
Page Count: 304
Tax/VAT will be calculated at check-out Price includes VAT (GST)
30% off
30% off
30% off
30% off
30% off
20% off
20% off
30% off
30% off
30% off
30% off
30% off
20% off
20% off
30% off
30% off
30% off
30% off
30% off
20% off
20% off
54.95
38.47
38.47
38.47
38.47
38.47
43.96
43.96
43.99
30.79
30.79
30.79
30.79
30.79
35.19
35.19
72.95
51.06
51.06
51.06
51.06
51.06
58.36
58.36
Unavailable
Price includes VAT (GST)
× DRM-Free

Easy - Download and start reading immediately. There’s no activation process to access eBooks; all eBooks are fully searchable, and enabled for copying, pasting, and printing.

Flexible - Read on multiple operating systems and devices. Easily read eBooks on smart phones, computers, or any eBook readers, including Kindle.

Open - Buy once, receive and download all available eBook formats, including PDF, EPUB, and Mobi (for Kindle).

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Description

Advances in Pharmacology and Therapeutics, Volume l: Receptors contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of receptors, their pharmacology, and their therapeutic applications. Topics covered range from opiate receptors and their endogenous ligands to membrane receptors in eukaryotic cells. Applications of binding to pharmacological research are also discussed. This volume is comprised of 29 chapters and opens with an overview of the chemistry and biochemistry of pituitary endorphins, paying particular attention to the correlation between the analgesic potency, receptor binding properties, preferred solution conformation, and metabolic stability of natural and synthetic opioid peptides. The reader is then introduced to the biosynthesis and release of the enkephalins; opiate receptors and their endogenous ligands; denervation supersensitivity in skeletal muscle; and biochemistry and physiology of dopaminergic and beta-adrenergic receptors in mammalian central nervous system. The following chapters explore the role of guanylnucleotides in the regulation of hormonally stimulated adenylate cyclase; interactions of cholera toxin with cell membranes; problems in studying hormone receptor binding; and the mechanism of action of anti-hormones. This book will be of interest to practitioners in biosciences, pharmacology, physiology, and medicine.

Table of Contents


Introduction

Opiate Receptors and their Endogenous Ligands

Chemistry and Biochemistry of Pituitary Endorphins

Multiple Opiate Receptors

Pituitary Endorphins: Recent Progress

The Biosynthesis and Release of the Enkephalins

Opiate Receptors: A) Functional Heterogeneity Demonstrated with an Apparently Irreversible Naloxone Derivative

B) Regulation by Guanine Nucleotides

Opiate Receptors, their Endogenous Ligands and the Development of Tolerance/Dependence

Physiological and Pathophysiological Relevance of the Endogenous Ligands of the Opiate Receptors

Membrane Receptors in E ucaryotic Cells

Multiple Classes of Muscarinic Receptor Binding Sites in the Brain

Biophysical Aspects of Agonist Action at Frog Endplate

Some Observations on Denervation Supersensitivity in Skeletal Muscle

Structural and Functional Properties of the Acetylcholine-Regulator

Glutamate Receptors in Eucaryotes

Biochemistry and Physiology of Dopaminergic and Beta-Adrenergic Receptors in Mammalian Central Nervous System

Beta-Adrenergic Receptors in C6 Glioma Cells and Central Nervous System

Recent Studies on Opiate Receptors

The Role of Quanylnucleotides in the Regulation of Hormonally Stimulated Adenylate Cyclase

Catecholamine-Sensitive Adenylate Cyclase: Identification and Partial Characterization of Some of its Components

Interactions of Cholera Toxin with Cell Membranes

Hybridization of Hormone Receptors with Adenylate Cyclase Systems of Different Cells

Receptor Binding Studies of Beta-Adrenergic Receptors: New Insights into Activation and Desensitization of Adenylate Cyclase

Applications of Binding to Pharmacological Research

Control of Hormone Receptor Levels and Function

Problems in Studying Hormone Receptor Binding

Methodological Approach to Radioligand Binding Studies of Adrenergic Receptors

Main Lectures

Synaptic Receptor Proteolipids: Isolation and Molecular Biology

The Mechanism of Action of Anti-Hormones

Angiotensin Receptors

Index

Details

No. of pages:
304
Language:
English
Copyright:
© Pergamon 1979
Published:
Imprint:
Pergamon
eBook ISBN:
9781483157962

About the Editor

J. Jacob